Efficacy of silymarin-nanohydrogle complex in attenuation of aflatoxins toxicity in Japanese quails
A 2 × 3 factorial experiment was conducted to investigate the effects of silymarin-nanohydrogle (0, 500 free; 500 nano) and a mycotoxin (0; 2.2 mg/kg), silymarin contaminated diet on productive performance and certain serum biochemical parameters using 72 Japanese quail chicks in days 7–35 of age. S...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2020-12-01
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| Series: | Italian Journal of Animal Science |
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| Online Access: | http://dx.doi.org/10.1080/1828051X.2020.1743782 |
| _version_ | 1819000408038703104 |
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| author | Behrouz Khaleghipour Heshmatollah Khosravinia Majid Toghiyani Arash Azarfar |
| author_facet | Behrouz Khaleghipour Heshmatollah Khosravinia Majid Toghiyani Arash Azarfar |
| author_sort | Behrouz Khaleghipour |
| collection | DOAJ |
| description | A 2 × 3 factorial experiment was conducted to investigate the effects of silymarin-nanohydrogle (0, 500 free; 500 nano) and a mycotoxin (0; 2.2 mg/kg), silymarin contaminated diet on productive performance and certain serum biochemical parameters using 72 Japanese quail chicks in days 7–35 of age. Six experimental treatments consisting inclusion of 0 or 2.2 mg/kg aflatoxins in a basal diet fed to the birds receiving 0 or 500 mg/L silymarin in two free- or nanohydrogle forms via drinking water. Daily weight gain (DWG) and European production index (EPI) reduced by 6.7% and 13.6% while feed intake (FI) and FCR increased by 3.76% and 12% in the birds fed on the diet containing 2.2 mg/kg aflatoxin, respectively (p < .05). Administration of silymarin-nanohydrogle through drinking water improved FI and DWG by 3.7% and 8.1%, respectively (p < .05). Mean serum alkaline phosphatase (ALP) activity elevated by 26.1% and serum concentration of total protein (TP), glucose (GLU) and high density lipoproteins (HDL) declined by 14.4%, 6.1% and 27.1% in the birds fed on the aflatoxin-contaminated diet, respectively (p < .05). Mean serum concentration of BUN (86.4%) and GLU (12.0%) increased and Ca (10.3%) decreased in birds receiving 500 mg/kg silymarin-nanohydrogle (p < .05). The birds receiving silymarin-nanohydrogle in drinking water showed lesser liver and spleen percentage (p < .05). It was concluded that inclusion of 500 mg/kg silymarin-nanohydrogle in drinking water could significantly compensate the impaired growth performance and alter hepatic function in Japanese quails fed on a diet contaminating 2.2 mg aflatoxins.Highlights Feeding diets contaminated with 2.2 mg aflatoxins/kg suppressed growth performance and impaired hepatic function in Japanese quails. Inclusion of 500 mg/kg silymarin-nanohydrogle in drinking water alleviated the adverse impact of aflatoxins on broilers’ performance and partially improved liver function. Greater levels of silymarin-nanohydrogle may relive the aflatoxin-caused intimidating alterations in liver and blood parameters in Japanese quails. |
| first_indexed | 2024-12-20T22:32:50Z |
| format | Article |
| id | doaj.art-d170f99563bf4b229fdeb60e9831cdac |
| institution | Directory Open Access Journal |
| issn | 1594-4077 1828-051X |
| language | English |
| last_indexed | 2024-12-20T22:32:50Z |
| publishDate | 2020-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Italian Journal of Animal Science |
| spelling | doaj.art-d170f99563bf4b229fdeb60e9831cdac2022-12-21T19:24:41ZengTaylor & Francis GroupItalian Journal of Animal Science1594-40771828-051X2020-12-0119135135910.1080/1828051X.2020.17437821743782Efficacy of silymarin-nanohydrogle complex in attenuation of aflatoxins toxicity in Japanese quailsBehrouz Khaleghipour0Heshmatollah Khosravinia1Majid Toghiyani2Arash Azarfar3Department of Animal Sciences, Agriculture Faculty, Lorestan UniversityDepartment of Animal Sciences, Agriculture Faculty, Lorestan UniversityDepartment of Animal Sciences, Agriculture Faculty, Islamic Azad University Khorasgan BranchDepartment of Animal Sciences, Agriculture Faculty, Lorestan UniversityA 2 × 3 factorial experiment was conducted to investigate the effects of silymarin-nanohydrogle (0, 500 free; 500 nano) and a mycotoxin (0; 2.2 mg/kg), silymarin contaminated diet on productive performance and certain serum biochemical parameters using 72 Japanese quail chicks in days 7–35 of age. Six experimental treatments consisting inclusion of 0 or 2.2 mg/kg aflatoxins in a basal diet fed to the birds receiving 0 or 500 mg/L silymarin in two free- or nanohydrogle forms via drinking water. Daily weight gain (DWG) and European production index (EPI) reduced by 6.7% and 13.6% while feed intake (FI) and FCR increased by 3.76% and 12% in the birds fed on the diet containing 2.2 mg/kg aflatoxin, respectively (p < .05). Administration of silymarin-nanohydrogle through drinking water improved FI and DWG by 3.7% and 8.1%, respectively (p < .05). Mean serum alkaline phosphatase (ALP) activity elevated by 26.1% and serum concentration of total protein (TP), glucose (GLU) and high density lipoproteins (HDL) declined by 14.4%, 6.1% and 27.1% in the birds fed on the aflatoxin-contaminated diet, respectively (p < .05). Mean serum concentration of BUN (86.4%) and GLU (12.0%) increased and Ca (10.3%) decreased in birds receiving 500 mg/kg silymarin-nanohydrogle (p < .05). The birds receiving silymarin-nanohydrogle in drinking water showed lesser liver and spleen percentage (p < .05). It was concluded that inclusion of 500 mg/kg silymarin-nanohydrogle in drinking water could significantly compensate the impaired growth performance and alter hepatic function in Japanese quails fed on a diet contaminating 2.2 mg aflatoxins.Highlights Feeding diets contaminated with 2.2 mg aflatoxins/kg suppressed growth performance and impaired hepatic function in Japanese quails. Inclusion of 500 mg/kg silymarin-nanohydrogle in drinking water alleviated the adverse impact of aflatoxins on broilers’ performance and partially improved liver function. Greater levels of silymarin-nanohydrogle may relive the aflatoxin-caused intimidating alterations in liver and blood parameters in Japanese quails.http://dx.doi.org/10.1080/1828051X.2020.1743782aflatoxinhepatoprotectivenanohydroglequailsilymarin |
| spellingShingle | Behrouz Khaleghipour Heshmatollah Khosravinia Majid Toghiyani Arash Azarfar Efficacy of silymarin-nanohydrogle complex in attenuation of aflatoxins toxicity in Japanese quails Italian Journal of Animal Science aflatoxin hepatoprotective nanohydrogle quail silymarin |
| title | Efficacy of silymarin-nanohydrogle complex in attenuation of aflatoxins toxicity in Japanese quails |
| title_full | Efficacy of silymarin-nanohydrogle complex in attenuation of aflatoxins toxicity in Japanese quails |
| title_fullStr | Efficacy of silymarin-nanohydrogle complex in attenuation of aflatoxins toxicity in Japanese quails |
| title_full_unstemmed | Efficacy of silymarin-nanohydrogle complex in attenuation of aflatoxins toxicity in Japanese quails |
| title_short | Efficacy of silymarin-nanohydrogle complex in attenuation of aflatoxins toxicity in Japanese quails |
| title_sort | efficacy of silymarin nanohydrogle complex in attenuation of aflatoxins toxicity in japanese quails |
| topic | aflatoxin hepatoprotective nanohydrogle quail silymarin |
| url | http://dx.doi.org/10.1080/1828051X.2020.1743782 |
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