Bovine Lactoferrin-Induced CCL1 Expression Involves Distinct Receptors in Monocyte-Derived Dendritic Cells and Their Monocyte Precursors

Bovine Lactoferrin-Induced CCL1 Expression Involves Distinct Receptors in Monocyte-Derived Dendritic Cells and Their Monocyte Precursors

Lactoferrin (LF) exhibits a wide range of immunomodulatory activities including modulation of cytokine and chemokine secretion. In this study, we demonstrate that bovine LF (bLF) up-modulates, in a concentration- and time-dependent manner, CCL1 secretion in monocytes (Mo) at the early stage of diffe...

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Bibliographic Details
Main Authors: Daniela Latorre, Nadia Pulvirenti, Daniela Angela Covino, Barbara Varano, Cristina Purificato, Gabriella Rainaldi, Maria Cristina Gauzzi, Laura Fantuzzi, Lucia Conti, Gloria Donninelli, Manuela Del Cornò, Michela Sabbatucci, Sandra Gessani, Patrizia Puddu
Format: Article
Language:English
Published: MDPI AG 2015-12-01
Series:Toxins
Subjects:
monocyte
dendritic cell
lactoferrin
CCL1
surface receptors
Online Access:http://www.mdpi.com/2072-6651/7/12/4897

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