Environmental, climatic and host population risk factors of human cystic echinococcosis in southwest of Iran
Abstract Background Cystic echinococcosis (CE), a worldwide zoonotic disease, is affected by various biological and environmental factors. We investigated dog/livestock populations, climatic and environmental factors influencing the distribution of human CE cases in Fars province, southwest Iran. Me...
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| Format: | Article |
| Language: | English |
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BMC
2020-10-01
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| Series: | BMC Public Health |
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| Online Access: | http://link.springer.com/article/10.1186/s12889-020-09638-w |
| _version_ | 1818998527849660416 |
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| author | Mohammad Amin Ghatee Koorosh Nikaein Walter Robert Taylor Mehdi Karamian Hasan Alidadi Zahra Kanannejad Faezeh Sehatpour Fateme Zarei Gholamreza Pouladfar |
| author_facet | Mohammad Amin Ghatee Koorosh Nikaein Walter Robert Taylor Mehdi Karamian Hasan Alidadi Zahra Kanannejad Faezeh Sehatpour Fateme Zarei Gholamreza Pouladfar |
| author_sort | Mohammad Amin Ghatee |
| collection | DOAJ |
| description | Abstract Background Cystic echinococcosis (CE), a worldwide zoonotic disease, is affected by various biological and environmental factors. We investigated dog/livestock populations, climatic and environmental factors influencing the distribution of human CE cases in Fars province, southwest Iran. Methods We mapped the addresses of 266 hospitalised CE patients (2004–2014) and studied the effects of different temperature models, mean annual rainfall and humidity, number of frosty days, slope, latitude, land covers, close proximity to nomads travel routes, livestock and dog densities on the occurrence of CE using geographical information systems approach. Data were analyzed by logistic regression. Results In the multivariate model predicting CE, living in an urban setting and densities of cattle and dogs were the most important CE predictors, sequentially. Dry (rained) farm, density of camel and sheep, close proximity to nomads travel routes, humidity, and slope also were considered as the determinants of CE distribution, when analyzed independently. Slope had a negative correlation with CE while temperature, frost days and latitude were not associated with CE. Conclusions In our study, an urban setting was the most important risk factor and likely due to a combination of the high density of key life cycle hosts, dogs and livestock, a large human susceptible population and the high number of abattoirs. Farmland and humidity were highly suggestive risk factors and these conditions support the increased survival of Echinococcus granulosus eggs in the soil. These findings support the development of strategies for control of disease. More research is needed test optimal interventions. |
| first_indexed | 2024-12-20T22:02:57Z |
| format | Article |
| id | doaj.art-d174f1a8a0804550b1350b3e39f12dea |
| institution | Directory Open Access Journal |
| issn | 1471-2458 |
| language | English |
| last_indexed | 2024-12-20T22:02:57Z |
| publishDate | 2020-10-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Public Health |
| spelling | doaj.art-d174f1a8a0804550b1350b3e39f12dea2022-12-21T19:25:19ZengBMCBMC Public Health1471-24582020-10-0120111310.1186/s12889-020-09638-wEnvironmental, climatic and host population risk factors of human cystic echinococcosis in southwest of IranMohammad Amin Ghatee0Koorosh Nikaein1Walter Robert Taylor2Mehdi Karamian3Hasan Alidadi4Zahra Kanannejad5Faezeh Sehatpour6Fateme Zarei7Gholamreza Pouladfar8Cellular and Molecular Research Center, Yasuj University of Medical SciencesStudent Research Committee, Yasuj University of Medical SciencesMahidol Oxford Tropical Medicine Research UnitDepartment of Parasitology and Mycology, School of Medicine, Zanjan University of Medical SciencesStudent Research Committee, Yasuj University of Medical SciencesAllergy Research Center, Shiraz University of Medical SciencesStudent Research Committee, Shiraz University of Medical SciencesStudent Research Committee, Shiraz University of Medical SciencesProfessor Alborzi Clinical Microbiology Research Center, Department of Paediatrics, Nemazee Teaching Hospital, School of Medicine, Shiraz University of Medical SciencesAbstract Background Cystic echinococcosis (CE), a worldwide zoonotic disease, is affected by various biological and environmental factors. We investigated dog/livestock populations, climatic and environmental factors influencing the distribution of human CE cases in Fars province, southwest Iran. Methods We mapped the addresses of 266 hospitalised CE patients (2004–2014) and studied the effects of different temperature models, mean annual rainfall and humidity, number of frosty days, slope, latitude, land covers, close proximity to nomads travel routes, livestock and dog densities on the occurrence of CE using geographical information systems approach. Data were analyzed by logistic regression. Results In the multivariate model predicting CE, living in an urban setting and densities of cattle and dogs were the most important CE predictors, sequentially. Dry (rained) farm, density of camel and sheep, close proximity to nomads travel routes, humidity, and slope also were considered as the determinants of CE distribution, when analyzed independently. Slope had a negative correlation with CE while temperature, frost days and latitude were not associated with CE. Conclusions In our study, an urban setting was the most important risk factor and likely due to a combination of the high density of key life cycle hosts, dogs and livestock, a large human susceptible population and the high number of abattoirs. Farmland and humidity were highly suggestive risk factors and these conditions support the increased survival of Echinococcus granulosus eggs in the soil. These findings support the development of strategies for control of disease. More research is needed test optimal interventions.http://link.springer.com/article/10.1186/s12889-020-09638-wCystic echinococcosisGISClimateLivestockEnvironment |
| spellingShingle | Mohammad Amin Ghatee Koorosh Nikaein Walter Robert Taylor Mehdi Karamian Hasan Alidadi Zahra Kanannejad Faezeh Sehatpour Fateme Zarei Gholamreza Pouladfar Environmental, climatic and host population risk factors of human cystic echinococcosis in southwest of Iran BMC Public Health Cystic echinococcosis GIS Climate Livestock Environment |
| title | Environmental, climatic and host population risk factors of human cystic echinococcosis in southwest of Iran |
| title_full | Environmental, climatic and host population risk factors of human cystic echinococcosis in southwest of Iran |
| title_fullStr | Environmental, climatic and host population risk factors of human cystic echinococcosis in southwest of Iran |
| title_full_unstemmed | Environmental, climatic and host population risk factors of human cystic echinococcosis in southwest of Iran |
| title_short | Environmental, climatic and host population risk factors of human cystic echinococcosis in southwest of Iran |
| title_sort | environmental climatic and host population risk factors of human cystic echinococcosis in southwest of iran |
| topic | Cystic echinococcosis GIS Climate Livestock Environment |
| url | http://link.springer.com/article/10.1186/s12889-020-09638-w |
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