ERO1 alpha deficiency impairs angiogenesis by increasing N-glycosylation of a proangiogenic VEGFA

ERO1 alpha deficiency impairs angiogenesis by increasing N-glycosylation of a proangiogenic VEGFA

N-glycosylation and disulfide bond formation are two essential steps in protein folding that occur in the endoplasmic reticulum (ER) and reciprocally influence each other. Here, to analyze crosstalk between N-glycosylation and oxidation, we investigated how the protein disulfide oxidase ERO1-alpha a...

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Bibliographic Details
Main Authors: Ersilia Varone, Alexander Chernorudskiy, Alessandro Cherubini, Angela Cattaneo, Angela Bachi, Stefano Fumagalli, Gizem Erol, Marco Gobbi, Michael J. Lenardo, Nica Borgese, Ester Zito
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Redox Biology
Subjects:
ERO1 alpha
Oxidative folding
VEGFA
N-glycosylation
Angiogenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231722002270

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http://www.sciencedirect.com/science/article/pii/S2213231722002270

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