Cancer/testis antigen‐Plac1 promotes invasion and metastasis of breast cancer through Furin/NICD/PTEN signaling pathway

Cancer/testis antigen‐Plac1 promotes invasion and metastasis of breast cancer through Furin/NICD/PTEN signaling pathway

Placenta‐specific protein 1 (Plac1) is a cancer/testis antigen that plays a critical role in promoting cancer initiation and progression. However, the clinical significance and mechanism of Plac1 in cancer progression remain elusive. Here, we report that Plac1 is an important oncogenic and prognosti...

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Bibliographic Details
Main Authors: Yongfei Li, Jiahui Chu, Jun Li, Wanting Feng, Fan Yang, Yifan Wang, Yanhong Zhang, Chunxiao Sun, Mengzhu Yang, Shauna N. Vasilatos, Yi Huang, Ziyi Fu, Yongmei Yin
Format: Article
Language:English
Published: Wiley 2018-08-01
Series:Molecular Oncology
Subjects:
breast cancer
cancer metastasis
cancer/testis gene
immunotherapy targets
prognostic factor
Online Access:https://doi.org/10.1002/1878-0261.12311

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