Xanthan Gum Capped ZnO Microstars as a Promising Dietary Zinc Supplementation
Zinc is one of the essential trace elements, and plays an important role in human health. Severe zinc deficiency can negatively affect organs such as the epidermal, immune, central nervous, gastrointestinal, skeletal, and reproductive systems. In this study, we offered a novel biocompatible xanthan...
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| Format: | Article |
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MDPI AG
2019-03-01
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| Series: | Foods |
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| Online Access: | http://www.mdpi.com/2304-8158/8/3/88 |
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| author | Alireza Ebrahiminezhad Fatemeh Moeeni Seyedeh-Masoumeh Taghizadeh Mostafa Seifan Christine Bautista Donya Novin Younes Ghasemi Aydin Berenjian |
| author_facet | Alireza Ebrahiminezhad Fatemeh Moeeni Seyedeh-Masoumeh Taghizadeh Mostafa Seifan Christine Bautista Donya Novin Younes Ghasemi Aydin Berenjian |
| author_sort | Alireza Ebrahiminezhad |
| collection | DOAJ |
| description | Zinc is one of the essential trace elements, and plays an important role in human health. Severe zinc deficiency can negatively affect organs such as the epidermal, immune, central nervous, gastrointestinal, skeletal, and reproductive systems. In this study, we offered a novel biocompatible xanthan gum capped zinc oxide (ZnO) microstar as a potential dietary zinc supplementation for food fortification. Xanthan gum (XG) is a commercially important extracellular polysaccharide that is widely used in diverse fields such as the food, cosmetic, and pharmaceutical industries, due to its nontoxic and biocompatible properties. In this work, for the first time, we reported a green procedure for the synthesis of ZnO microstars using XG, as the stabilizing agent, without using any synthetic or toxic reagent. X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), and transmission electron microscopy (TEM) were used to study the structure, morphology, and size of the synthesized ZnO structures. The results showed that the synthesized structures were both hexagonal phase and starlike, with an average particle size of 358 nm. The effect of different dosages of XG-capped ZnO nanoparticles (1–9 mM) against Gram-negative (Escherichia coli) and Gram-positive (Bacillus licheniformis, Bacillus subtilis, and Bacillus sphaericus) bacteria were also investigated. Based on the results, the fabricated XG-capped ZnO microstars showed a high level of biocompatibility with no antimicrobial effect against the tested microorganisms. The data suggested the potential of newly produced ZnO microstructures for a range of applications in dietary supplementation and food fortification. |
| first_indexed | 2024-12-16T18:07:44Z |
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| language | English |
| last_indexed | 2024-12-16T18:07:44Z |
| publishDate | 2019-03-01 |
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| record_format | Article |
| series | Foods |
| spelling | doaj.art-d1791cc4ebe44c83ab8236b4325c3cb82022-12-21T22:21:52ZengMDPI AGFoods2304-81582019-03-01838810.3390/foods8030088foods8030088Xanthan Gum Capped ZnO Microstars as a Promising Dietary Zinc SupplementationAlireza Ebrahiminezhad0Fatemeh Moeeni1Seyedeh-Masoumeh Taghizadeh2Mostafa Seifan3Christine Bautista4Donya Novin5Younes Ghasemi6Aydin Berenjian7Department of Medical Nanotechnology, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz 71348, IranDepartment of Pharmaceutical Biotechnology, School of Pharmacy and Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz 71348, IranDepartment of Pharmaceutical Biotechnology, School of Pharmacy and Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz 71348, IranSchool of Engineering, Faculty of Sciences and Engineering, University of Waikato, Hamilton 3216, New ZealandSchool of Engineering, Faculty of Sciences and Engineering, University of Waikato, Hamilton 3216, New ZealandSchool of Engineering, Faculty of Sciences and Engineering, University of Waikato, Hamilton 3216, New ZealandDepartment of Pharmaceutical Biotechnology, School of Pharmacy and Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz 71348, IranSchool of Engineering, Faculty of Sciences and Engineering, University of Waikato, Hamilton 3216, New ZealandZinc is one of the essential trace elements, and plays an important role in human health. Severe zinc deficiency can negatively affect organs such as the epidermal, immune, central nervous, gastrointestinal, skeletal, and reproductive systems. In this study, we offered a novel biocompatible xanthan gum capped zinc oxide (ZnO) microstar as a potential dietary zinc supplementation for food fortification. Xanthan gum (XG) is a commercially important extracellular polysaccharide that is widely used in diverse fields such as the food, cosmetic, and pharmaceutical industries, due to its nontoxic and biocompatible properties. In this work, for the first time, we reported a green procedure for the synthesis of ZnO microstars using XG, as the stabilizing agent, without using any synthetic or toxic reagent. X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), and transmission electron microscopy (TEM) were used to study the structure, morphology, and size of the synthesized ZnO structures. The results showed that the synthesized structures were both hexagonal phase and starlike, with an average particle size of 358 nm. The effect of different dosages of XG-capped ZnO nanoparticles (1–9 mM) against Gram-negative (Escherichia coli) and Gram-positive (Bacillus licheniformis, Bacillus subtilis, and Bacillus sphaericus) bacteria were also investigated. Based on the results, the fabricated XG-capped ZnO microstars showed a high level of biocompatibility with no antimicrobial effect against the tested microorganisms. The data suggested the potential of newly produced ZnO microstructures for a range of applications in dietary supplementation and food fortification.http://www.mdpi.com/2304-8158/8/3/88xanthan gumZnO microparticlesZnO microstarsbacteriasupplementationfood fortification |
| spellingShingle | Alireza Ebrahiminezhad Fatemeh Moeeni Seyedeh-Masoumeh Taghizadeh Mostafa Seifan Christine Bautista Donya Novin Younes Ghasemi Aydin Berenjian Xanthan Gum Capped ZnO Microstars as a Promising Dietary Zinc Supplementation Foods xanthan gum ZnO microparticles ZnO microstars bacteria supplementation food fortification |
| title | Xanthan Gum Capped ZnO Microstars as a Promising Dietary Zinc Supplementation |
| title_full | Xanthan Gum Capped ZnO Microstars as a Promising Dietary Zinc Supplementation |
| title_fullStr | Xanthan Gum Capped ZnO Microstars as a Promising Dietary Zinc Supplementation |
| title_full_unstemmed | Xanthan Gum Capped ZnO Microstars as a Promising Dietary Zinc Supplementation |
| title_short | Xanthan Gum Capped ZnO Microstars as a Promising Dietary Zinc Supplementation |
| title_sort | xanthan gum capped zno microstars as a promising dietary zinc supplementation |
| topic | xanthan gum ZnO microparticles ZnO microstars bacteria supplementation food fortification |
| url | http://www.mdpi.com/2304-8158/8/3/88 |
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