Receptor tyrosine kinases and downstream pathways as druggable targets for cancer treatment: the current arsenal of inhibitors
Abstract Searching for targets that allow pharmacological inhibition of cell proliferation in over-proliferative states, such as cancer, leads us to finely understand the complex mechanisms orchestrating the perfect control of mitosis number, frequency and pace as well as the molecular arrangements...
Main Authors: | Wagner Ricardo Montor, Andrei Ronaldo Oliveira Silva Escartin Salas, Fabiana Henriques Machado de Melo |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2018-02-01
|
Series: | Molecular Cancer |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12943-018-0792-2 |
Similar Items
-
Protein tyrosine kinases in Schistosoma mansoni
by: Diana Bahia, et al.
Published: (2006-10-01) -
Novel Tyrosine Kinase Targets in Urothelial Carcinoma
by: Javier Torres-Jiménez, et al.
Published: (2021-01-01) -
KRAS Pathway Alterations in Malignant Pleural Mesothelioma: An Underestimated Player
by: Lilith Trassl, et al.
Published: (2022-09-01) -
Lemur Tyrosine Kinases and Prostate Cancer: A Literature Review
by: Elena Ferrari, et al.
Published: (2021-05-01) -
The Myristylation Motif of Pto Is Not Required for Disease Resistance
by: Ying-Tsu Loh, et al.
Published: (1998-06-01)