Outcome of primary orbital lymphoma treated with induction chemotherapy followed by conformal radiotherapy
Purpose: To analyze the clinical outcome of primary orbital lymphoma (POL) patients treated with a combined modality approach with local radiotherapy after induction chemotherapy. Methodology: We retrospectively retrieved demographic, treatment and outcome data of patients treated for POL from 2000...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2015-09-01
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| Series: | Journal of the Egyptian National Cancer Institute |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1110036215000345 |
| _version_ | 1818561858345369600 |
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| author | Supriya Mallick Sudeep Das Rony Benson Vikas Roshan Suman Bhasker |
| author_facet | Supriya Mallick Sudeep Das Rony Benson Vikas Roshan Suman Bhasker |
| author_sort | Supriya Mallick |
| collection | DOAJ |
| description | Purpose: To analyze the clinical outcome of primary orbital lymphoma (POL) patients treated with a combined modality approach with local radiotherapy after induction chemotherapy.
Methodology: We retrospectively retrieved demographic, treatment and outcome data of patients treated for POL from 2000 to 2010. The charts were reviewed and the data were tabulated in a predesigned pro-forma.
Results: 23 patients of POL were found evaluable. Median age was 55 years (range 24–70 years). Of 23 patients, 15 were male and 8 female, making the male:female ratio approximately 1.9:1. Patients were thoroughly evaluated and staged. All but one patient received multi agent chemotherapy. Radiotherapy was delivered for all cases. Radiation was delivered by 3DCRT technique. Median dose of radiation was 45 Gy (range 20–45 Gy). Median follow up was 26.8 months. None of the patients had any evidence of local failure or systemic progression.
Conclusion: A combined modality therapy with a combination of CHOP/COP based chemotherapy and moderate dose of radiotherapy imparts excellent long term local and systemic disease control. |
| first_indexed | 2024-12-14T00:56:13Z |
| format | Article |
| id | doaj.art-d17a4fe5862345b1ac4d30576826b88e |
| institution | Directory Open Access Journal |
| issn | 1110-0362 |
| language | English |
| last_indexed | 2024-12-14T00:56:13Z |
| publishDate | 2015-09-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Journal of the Egyptian National Cancer Institute |
| spelling | doaj.art-d17a4fe5862345b1ac4d30576826b88e2022-12-21T23:23:32ZengSpringerOpenJournal of the Egyptian National Cancer Institute1110-03622015-09-0127311311710.1016/j.jnci.2015.04.003Outcome of primary orbital lymphoma treated with induction chemotherapy followed by conformal radiotherapySupriya MallickSudeep DasRony BensonVikas RoshanSuman BhaskerPurpose: To analyze the clinical outcome of primary orbital lymphoma (POL) patients treated with a combined modality approach with local radiotherapy after induction chemotherapy. Methodology: We retrospectively retrieved demographic, treatment and outcome data of patients treated for POL from 2000 to 2010. The charts were reviewed and the data were tabulated in a predesigned pro-forma. Results: 23 patients of POL were found evaluable. Median age was 55 years (range 24–70 years). Of 23 patients, 15 were male and 8 female, making the male:female ratio approximately 1.9:1. Patients were thoroughly evaluated and staged. All but one patient received multi agent chemotherapy. Radiotherapy was delivered for all cases. Radiation was delivered by 3DCRT technique. Median dose of radiation was 45 Gy (range 20–45 Gy). Median follow up was 26.8 months. None of the patients had any evidence of local failure or systemic progression. Conclusion: A combined modality therapy with a combination of CHOP/COP based chemotherapy and moderate dose of radiotherapy imparts excellent long term local and systemic disease control.http://www.sciencedirect.com/science/article/pii/S1110036215000345OrbitalLymphomaRadiotherapyChemotherapyConformal |
| spellingShingle | Supriya Mallick Sudeep Das Rony Benson Vikas Roshan Suman Bhasker Outcome of primary orbital lymphoma treated with induction chemotherapy followed by conformal radiotherapy Journal of the Egyptian National Cancer Institute Orbital Lymphoma Radiotherapy Chemotherapy Conformal |
| title | Outcome of primary orbital lymphoma treated with induction chemotherapy followed by conformal radiotherapy |
| title_full | Outcome of primary orbital lymphoma treated with induction chemotherapy followed by conformal radiotherapy |
| title_fullStr | Outcome of primary orbital lymphoma treated with induction chemotherapy followed by conformal radiotherapy |
| title_full_unstemmed | Outcome of primary orbital lymphoma treated with induction chemotherapy followed by conformal radiotherapy |
| title_short | Outcome of primary orbital lymphoma treated with induction chemotherapy followed by conformal radiotherapy |
| title_sort | outcome of primary orbital lymphoma treated with induction chemotherapy followed by conformal radiotherapy |
| topic | Orbital Lymphoma Radiotherapy Chemotherapy Conformal |
| url | http://www.sciencedirect.com/science/article/pii/S1110036215000345 |
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