Whole genome sequencing data of Leptospira weilii and Leptospira kirschneri isolated from human subjects of Sri Lanka
Leptospirosis is a re-emerging zoonotic disease. This article reports the complete genome sequences of three novel strains of Genus Leptospira: two from the species Leptospira weilii (FMAS_RT1, FMAS_PD2) and one from Leptospira kirschneri (FMAS_PN5). These isolates were recovered from the blood samp...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-02-01
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| Series: | Data in Brief |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352340923009022 |
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| author | Indika Senavirathna Dinesha Jayasundara Janith Warnasekara Michael A. Matthias Joseph M. Vinetz Suneth Agampodi |
| author_facet | Indika Senavirathna Dinesha Jayasundara Janith Warnasekara Michael A. Matthias Joseph M. Vinetz Suneth Agampodi |
| author_sort | Indika Senavirathna |
| collection | DOAJ |
| description | Leptospirosis is a re-emerging zoonotic disease. This article reports the complete genome sequences of three novel strains of Genus Leptospira: two from the species Leptospira weilii (FMAS_RT1, FMAS_PD2) and one from Leptospira kirschneri (FMAS_PN5). These isolates were recovered from the blood samples of acute febrile patients in different geographical and climatic zones of Sri Lanka. High-quality genomic DNA was extracted from the three isolates in mid-log phase cultures. Whole genome sequencing was conducted using the PacBio Single Molecule Real-Time (SMRT) platform to identify the species, genome features, and novelty of the strains. The annotation was conducted using RAST (Rapid Annotation Using Subsystem Technology version 2.0) and the NCBI Prokaryotic Genome Annotation Pipeline. The genome sequences of three isolates have been deposited in the Mendeley data repository and the National Center for Biotechnology Information (NCBI) repository. This data will be useful for future researchers when conducting comparative genomic analysis, revealing the exact mechanism of pathogenesis of leptospirosis and developing molecular diagnostic tools for early detection. |
| first_indexed | 2024-03-08T03:30:42Z |
| format | Article |
| id | doaj.art-d17f581048574c1ba512429f29e09615 |
| institution | Directory Open Access Journal |
| issn | 2352-3409 |
| language | English |
| last_indexed | 2024-03-08T03:30:42Z |
| publishDate | 2024-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Data in Brief |
| spelling | doaj.art-d17f581048574c1ba512429f29e096152024-02-11T05:10:16ZengElsevierData in Brief2352-34092024-02-0152109840Whole genome sequencing data of Leptospira weilii and Leptospira kirschneri isolated from human subjects of Sri LankaIndika Senavirathna0Dinesha Jayasundara1Janith Warnasekara2Michael A. Matthias3Joseph M. Vinetz4Suneth Agampodi5Leptospirosis Research Laboratory, Department of Community Medicine, Faculty of Medicine and Allied Sciences, Rajarata University of Sri Lanka, Sri Lanka; Department of Biochemistry, Faculty of Medicine and Allied Sciences, Rajarata University of Sri Lanka, Sri Lanka; Corresponding author.Leptospirosis Research Laboratory, Department of Community Medicine, Faculty of Medicine and Allied Sciences, Rajarata University of Sri Lanka, Sri Lanka; Department of Microbiology, Faculty of Medicine and Allied Sciences, Rajarata University of Sri Lanka, Sri LankaLeptospirosis Research Laboratory, Department of Community Medicine, Faculty of Medicine and Allied Sciences, Rajarata University of Sri Lanka, Sri Lanka; Department of Community Medicine, Faculty of Medicine and Allied Sciences, Rajarata University of Sri Lanka, Sri LankaSection of Infectious Disease, Department of Internal Medicine, School of Medicine, Yale University, New Haven, CT, USASection of Infectious Disease, Department of Internal Medicine, School of Medicine, Yale University, New Haven, CT, USASection of Infectious Disease, Department of Internal Medicine, School of Medicine, Yale University, New Haven, CT, USA; International Vaccine Institute, Seoul, Republic of Korea; Center for Public Health, Anuradhapura, Sri LankaLeptospirosis is a re-emerging zoonotic disease. This article reports the complete genome sequences of three novel strains of Genus Leptospira: two from the species Leptospira weilii (FMAS_RT1, FMAS_PD2) and one from Leptospira kirschneri (FMAS_PN5). These isolates were recovered from the blood samples of acute febrile patients in different geographical and climatic zones of Sri Lanka. High-quality genomic DNA was extracted from the three isolates in mid-log phase cultures. Whole genome sequencing was conducted using the PacBio Single Molecule Real-Time (SMRT) platform to identify the species, genome features, and novelty of the strains. The annotation was conducted using RAST (Rapid Annotation Using Subsystem Technology version 2.0) and the NCBI Prokaryotic Genome Annotation Pipeline. The genome sequences of three isolates have been deposited in the Mendeley data repository and the National Center for Biotechnology Information (NCBI) repository. This data will be useful for future researchers when conducting comparative genomic analysis, revealing the exact mechanism of pathogenesis of leptospirosis and developing molecular diagnostic tools for early detection.http://www.sciencedirect.com/science/article/pii/S2352340923009022PacBio single molecule real-timeLeptospira kirschneriLeptospira weiliiWhole genomeFMAS_RT1Bio-sample |
| spellingShingle | Indika Senavirathna Dinesha Jayasundara Janith Warnasekara Michael A. Matthias Joseph M. Vinetz Suneth Agampodi Whole genome sequencing data of Leptospira weilii and Leptospira kirschneri isolated from human subjects of Sri Lanka Data in Brief PacBio single molecule real-time Leptospira kirschneri Leptospira weilii Whole genome FMAS_RT1 Bio-sample |
| title | Whole genome sequencing data of Leptospira weilii and Leptospira kirschneri isolated from human subjects of Sri Lanka |
| title_full | Whole genome sequencing data of Leptospira weilii and Leptospira kirschneri isolated from human subjects of Sri Lanka |
| title_fullStr | Whole genome sequencing data of Leptospira weilii and Leptospira kirschneri isolated from human subjects of Sri Lanka |
| title_full_unstemmed | Whole genome sequencing data of Leptospira weilii and Leptospira kirschneri isolated from human subjects of Sri Lanka |
| title_short | Whole genome sequencing data of Leptospira weilii and Leptospira kirschneri isolated from human subjects of Sri Lanka |
| title_sort | whole genome sequencing data of leptospira weilii and leptospira kirschneri isolated from human subjects of sri lanka |
| topic | PacBio single molecule real-time Leptospira kirschneri Leptospira weilii Whole genome FMAS_RT1 Bio-sample |
| url | http://www.sciencedirect.com/science/article/pii/S2352340923009022 |
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