Herbal melanin inhibits colorectal cancer cell proliferation by altering redox balance, inducing apoptosis, and modulating MAPK signaling

Herbal melanin inhibits colorectal cancer cell proliferation by altering redox balance, inducing apoptosis, and modulating MAPK signaling

Abstract Background Colorectal carcinoma is one of the most deadly cancers that requests effective and safe chemotherapy. Evaluation of natural product-based anticancer drugs as adjuvant treatment with fewer side effects is largely unexplored research fields. Herbal melanin (HM) is an extract of the...

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Bibliographic Details
Main Authors: Omar Al-Obeed, Adila Salih El-Obeid, Sabine Matou-Nasri, Mansoor-Ali Vaali-Mohammed, Yazeid AlHaidan, Mohammed Elwatidy, Hamad Al Dosary, Zeyad Alehaideb, Khayal Alkhayal, Adil Haseeb, James McKerrow, Rehan Ahmad, Maha-Hamadien Abdulla
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Cancer Cell International
Subjects:
Herbal melanin
Colorectal cancer
Proliferation
Apoptosis
Reactive oxygen species
TLR4 receptor
Online Access:http://link.springer.com/article/10.1186/s12935-020-01206-x

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