Sepsis: source control

Sepsis is a life-threatening condition, which is manifested by the development of organ dysfunction due to generalized inflammation caused by the infection of various nature. Timely lesion debridement combined with adequate antibiotic therapy are important components of the successful treatment of se...

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Main Authors: V. V. Kulabukhov, N. A. Zubareva, P. A. Yartsev
Format: Article
Language:Russian
Published: New Terra Publishing House 2021-11-01
Series:Вестник анестезиологии и реаниматологии
Subjects:
Online Access:https://www.vair-journal.com/jour/article/view/584
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author V. V. Kulabukhov
N. A. Zubareva
P. A. Yartsev
author_facet V. V. Kulabukhov
N. A. Zubareva
P. A. Yartsev
author_sort V. V. Kulabukhov
collection DOAJ
description Sepsis is a life-threatening condition, which is manifested by the development of organ dysfunction due to generalized inflammation caused by the infection of various nature. Timely lesion debridement combined with adequate antibiotic therapy are important components of the successful treatment of sepsis. At the moment, there is no consensus about the volume and time of intervention in the development of surgical sepsis. The article discusses modern approaches to solving the problem of adequate sanitation of the source of infection. The results of few randomized trials in this area are presented.Source control is absolutely essential for the successful treatment of sepsis. However, it is difcult to create a unifed algorithm for surgical control for all cases due to different approaches depending on the infection location. Properly designed clinical trials are necessary to determine the optimal timing of surgery for sepsis and septic shock as least.
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spelling doaj.art-d18116f119544cab93b8e50ce05630412023-09-03T13:24:38ZrusNew Terra Publishing HouseВестник анестезиологии и реаниматологии2078-56582541-86532021-11-01185899610.21292/2078-5658-2021-18-5-89-96476Sepsis: source controlV. V. Kulabukhov0N. A. Zubareva1P. A. Yartsev2Научно-исследовательский институт скорой помощи им. Н. В. Склифосовского Департамента здравоохранения города МосквыПермский государственный медицинский университет им. акад. Е. А. ВагнераНаучно-исследовательский институт скорой помощи им. Н. В. Склифосовского Департамента здравоохранения города МосквыSepsis is a life-threatening condition, which is manifested by the development of organ dysfunction due to generalized inflammation caused by the infection of various nature. Timely lesion debridement combined with adequate antibiotic therapy are important components of the successful treatment of sepsis. At the moment, there is no consensus about the volume and time of intervention in the development of surgical sepsis. The article discusses modern approaches to solving the problem of adequate sanitation of the source of infection. The results of few randomized trials in this area are presented.Source control is absolutely essential for the successful treatment of sepsis. However, it is difcult to create a unifed algorithm for surgical control for all cases due to different approaches depending on the infection location. Properly designed clinical trials are necessary to determine the optimal timing of surgery for sepsis and septic shock as least.https://www.vair-journal.com/jour/article/view/584сепсисконтроль очагаинтраабдоминальные инфекцииинфекции кожи и мягких тканей
spellingShingle V. V. Kulabukhov
N. A. Zubareva
P. A. Yartsev
Sepsis: source control
Вестник анестезиологии и реаниматологии
сепсис
контроль очага
интраабдоминальные инфекции
инфекции кожи и мягких тканей
title Sepsis: source control
title_full Sepsis: source control
title_fullStr Sepsis: source control
title_full_unstemmed Sepsis: source control
title_short Sepsis: source control
title_sort sepsis source control
topic сепсис
контроль очага
интраабдоминальные инфекции
инфекции кожи и мягких тканей
url https://www.vair-journal.com/jour/article/view/584
work_keys_str_mv AT vvkulabukhov sepsissourcecontrol
AT nazubareva sepsissourcecontrol
AT payartsev sepsissourcecontrol