Microbiological Profile of Ocular Infection: A Large Retrospective Study
Background: We aimed to elucidate the pathogenic bacterial and fungal profiles of specimens obtained from suspected ocular infections at Farabi Eye Tertiary Referral Hospital, Tehran, Iran. Methods: In this cross-sectional study, we collected data from ocular specimens taken during the seven-yea...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Tehran University of Medical Sciences
2022-06-01
|
| Series: | Iranian Journal of Public Health |
| Subjects: | |
| Online Access: | https://ijph.tums.ac.ir/index.php/ijph/article/view/25350 |
| _version_ | 1818236010506485760 |
|---|---|
| author | Fahimeh Asadi-Amoli Zohreh Abedinifar Zohreh Nozarian Fatemeh Heidary Mahsa Haji Safar Ali Memar Athena Nezamabadi Reza Gharebaghi Narges Roustaei Maryam Parvizi |
| author_facet | Fahimeh Asadi-Amoli Zohreh Abedinifar Zohreh Nozarian Fatemeh Heidary Mahsa Haji Safar Ali Memar Athena Nezamabadi Reza Gharebaghi Narges Roustaei Maryam Parvizi |
| author_sort | Fahimeh Asadi-Amoli |
| collection | DOAJ |
| description |
Background: We aimed to elucidate the pathogenic bacterial and fungal profiles of specimens obtained from suspected ocular infections at Farabi Eye Tertiary Referral Hospital, Tehran, Iran.
Methods: In this cross-sectional study, we collected data from ocular specimens taken during the seven-year period of 2011 to 2018, and the results were then retrospectively analyzed. Samples had been obtained from patients who were investigated for ocular infections.
Results: Overall, 16,656 ocular samples were evaluated. The mean patient age was 48.31 ± 26.62 years. Most patients were men (60.33%), and men in the 7th decade of life were the largest represented group. The seasonal distributions of specimen collection sites followed the overall distribution of collection sites by year. Specimens obtained from the cornea were the most common (49.24%), also representing the largest number of specimens in all seasons. The most commonly isolated fungal microorganisms were Fusarium spp., followed by Aspergillus spp. and Candida albicans. Of the 6,556 specimens with positive bacterial cultures, 59% produced gram-positive bacteria, while the remainder produced gram-negative pathogens. The most commonly isolated bacteria were Pseudomonas aeruginosa (17.77%), Staphylococcus epidermidis (13.80%), Streptococcus pneumoniae (13.27%), S. viridans (12.23%), and S. aureus (11.18%).
Conclusion: Most submitted specimens were obtained from the cornea. The most commonly isolated fungal microorganisms were Fusarium spp., followed by Aspergillus spp. and C. albicans. The most commonly isolated bacteria were P. aeruginosa, followed by S. epidermidis and S. pneumoniae.
|
| first_indexed | 2024-12-12T12:03:04Z |
| format | Article |
| id | doaj.art-d183491be82248bc9bf8185c5ecdaced |
| institution | Directory Open Access Journal |
| issn | 2251-6085 2251-6093 |
| language | English |
| last_indexed | 2024-12-12T12:03:04Z |
| publishDate | 2022-06-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Public Health |
| spelling | doaj.art-d183491be82248bc9bf8185c5ecdaced2022-12-22T00:25:04ZengTehran University of Medical SciencesIranian Journal of Public Health2251-60852251-60932022-06-0151610.18502/ijph.v51i6.9699Microbiological Profile of Ocular Infection: A Large Retrospective StudyFahimeh Asadi-Amoli0Zohreh Abedinifar1Zohreh Nozarian2Fatemeh Heidary3Mahsa Haji Safar Ali Memar4Athena Nezamabadi5Reza Gharebaghi6Narges Roustaei7Maryam Parvizi8Pathology Department and Microbiology Unit, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, IranPathology Department and Microbiology Unit, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, IranPathology Department and Microbiology Unit, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, IranInternational Virtual Ophthalmic Research Center (IVORC), Austin, Texas, USAPathology Department and Microbiology Unit, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, IranPathology Department and Microbiology Unit, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, IranInternational Virtual Ophthalmic Research Center (IVORC), Austin, Texas, USADepartment of Biostatistics and Epidemiology, School of Health and Nutrition Sciences, Yasuj University of Medical Sciences, Yasuj, IranDepartment of Pathology, Mofid Children's Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran Background: We aimed to elucidate the pathogenic bacterial and fungal profiles of specimens obtained from suspected ocular infections at Farabi Eye Tertiary Referral Hospital, Tehran, Iran. Methods: In this cross-sectional study, we collected data from ocular specimens taken during the seven-year period of 2011 to 2018, and the results were then retrospectively analyzed. Samples had been obtained from patients who were investigated for ocular infections. Results: Overall, 16,656 ocular samples were evaluated. The mean patient age was 48.31 ± 26.62 years. Most patients were men (60.33%), and men in the 7th decade of life were the largest represented group. The seasonal distributions of specimen collection sites followed the overall distribution of collection sites by year. Specimens obtained from the cornea were the most common (49.24%), also representing the largest number of specimens in all seasons. The most commonly isolated fungal microorganisms were Fusarium spp., followed by Aspergillus spp. and Candida albicans. Of the 6,556 specimens with positive bacterial cultures, 59% produced gram-positive bacteria, while the remainder produced gram-negative pathogens. The most commonly isolated bacteria were Pseudomonas aeruginosa (17.77%), Staphylococcus epidermidis (13.80%), Streptococcus pneumoniae (13.27%), S. viridans (12.23%), and S. aureus (11.18%). Conclusion: Most submitted specimens were obtained from the cornea. The most commonly isolated fungal microorganisms were Fusarium spp., followed by Aspergillus spp. and C. albicans. The most commonly isolated bacteria were P. aeruginosa, followed by S. epidermidis and S. pneumoniae. https://ijph.tums.ac.ir/index.php/ijph/article/view/25350Microbiological profileOcular infectionBacterialFungalEyeOcular specimen |
| spellingShingle | Fahimeh Asadi-Amoli Zohreh Abedinifar Zohreh Nozarian Fatemeh Heidary Mahsa Haji Safar Ali Memar Athena Nezamabadi Reza Gharebaghi Narges Roustaei Maryam Parvizi Microbiological Profile of Ocular Infection: A Large Retrospective Study Iranian Journal of Public Health Microbiological profile Ocular infection Bacterial Fungal Eye Ocular specimen |
| title | Microbiological Profile of Ocular Infection: A Large Retrospective Study |
| title_full | Microbiological Profile of Ocular Infection: A Large Retrospective Study |
| title_fullStr | Microbiological Profile of Ocular Infection: A Large Retrospective Study |
| title_full_unstemmed | Microbiological Profile of Ocular Infection: A Large Retrospective Study |
| title_short | Microbiological Profile of Ocular Infection: A Large Retrospective Study |
| title_sort | microbiological profile of ocular infection a large retrospective study |
| topic | Microbiological profile Ocular infection Bacterial Fungal Eye Ocular specimen |
| url | https://ijph.tums.ac.ir/index.php/ijph/article/view/25350 |
| work_keys_str_mv | AT fahimehasadiamoli microbiologicalprofileofocularinfectionalargeretrospectivestudy AT zohrehabedinifar microbiologicalprofileofocularinfectionalargeretrospectivestudy AT zohrehnozarian microbiologicalprofileofocularinfectionalargeretrospectivestudy AT fatemehheidary microbiologicalprofileofocularinfectionalargeretrospectivestudy AT mahsahajisafaralimemar microbiologicalprofileofocularinfectionalargeretrospectivestudy AT athenanezamabadi microbiologicalprofileofocularinfectionalargeretrospectivestudy AT rezagharebaghi microbiologicalprofileofocularinfectionalargeretrospectivestudy AT nargesroustaei microbiologicalprofileofocularinfectionalargeretrospectivestudy AT maryamparvizi microbiologicalprofileofocularinfectionalargeretrospectivestudy |