Mathematical analysis of blood flow through an arterial segment with time‐dependent stenosis

A mathematical model is developed here with an aim to study the pulsatile flow of blood through an arterial segment having a time‐dependent stenosis. Blood is considered to consist of a core layer where erythrocytes are concentrated and a peripheral plasma layer that is free from erythrocytes. The p...

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Main Authors: Jagadis Chandra Misra, Sudi D. Adhikary, Gopal Chandra Shit
Format: Article
Language:English
Published: Vilnius Gediminas Technical University 2008-09-01
Series:Mathematical Modelling and Analysis
Subjects:
Online Access:https://journals.vgtu.lt/index.php/MMA/article/view/7026
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author Jagadis Chandra Misra
Sudi D. Adhikary
Gopal Chandra Shit
author_facet Jagadis Chandra Misra
Sudi D. Adhikary
Gopal Chandra Shit
author_sort Jagadis Chandra Misra
collection DOAJ
description A mathematical model is developed here with an aim to study the pulsatile flow of blood through an arterial segment having a time‐dependent stenosis. Blood is considered to consist of a core layer where erythrocytes are concentrated and a peripheral plasma layer that is free from erythrocytes. The plasma layer is taken to behave as a Newtonian fluid, while the core layer is represented by as a Casson fluid (non‐Newtonian) model. The pulsatile flow is analyzed by considering a periodic pressure gradient, which is a function of time. A perturbation analysis is employed to solve the governing differential equations by taking the Womersley frequency parameter to be small (α < 1). This is a realistic assumption for physiological fluid flows, particularly for flow of blood in small vessels. Using appropriate boundary conditions, analytical expressions for the velocity profile, the volumetric flow rate, the wall shear stress and the flow resistance have been derived. These expressions are computed numerically and the computational results are presented graphically, in order to illustrate the variation of different quantities that are of particular interest in the study. First Published Online: 14 Oct 2010
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spelling doaj.art-d18525bdc4144be89521f20ffbd7c04f2022-12-21T20:13:44ZengVilnius Gediminas Technical UniversityMathematical Modelling and Analysis1392-62921648-35102008-09-0113310.3846/1392-6292.2008.13.401-412Mathematical analysis of blood flow through an arterial segment with time‐dependent stenosisJagadis Chandra Misra0Sudi D. Adhikary1Gopal Chandra Shit2Department of Mathematics, Indian Institute of Technology, Kharagpur-721302, IndiaDepartment of Mathematics, Indian Institute of Technology, Kharagpur-721302, IndiaDepartment of Mathematics, Indian Institute of Technology, Kharagpur-721302, IndiaA mathematical model is developed here with an aim to study the pulsatile flow of blood through an arterial segment having a time‐dependent stenosis. Blood is considered to consist of a core layer where erythrocytes are concentrated and a peripheral plasma layer that is free from erythrocytes. The plasma layer is taken to behave as a Newtonian fluid, while the core layer is represented by as a Casson fluid (non‐Newtonian) model. The pulsatile flow is analyzed by considering a periodic pressure gradient, which is a function of time. A perturbation analysis is employed to solve the governing differential equations by taking the Womersley frequency parameter to be small (α < 1). This is a realistic assumption for physiological fluid flows, particularly for flow of blood in small vessels. Using appropriate boundary conditions, analytical expressions for the velocity profile, the volumetric flow rate, the wall shear stress and the flow resistance have been derived. These expressions are computed numerically and the computational results are presented graphically, in order to illustrate the variation of different quantities that are of particular interest in the study. First Published Online: 14 Oct 2010https://journals.vgtu.lt/index.php/MMA/article/view/7026Pulsatile flowCasson modelTwo-layer modelTime-dependent stenosis
spellingShingle Jagadis Chandra Misra
Sudi D. Adhikary
Gopal Chandra Shit
Mathematical analysis of blood flow through an arterial segment with time‐dependent stenosis
Mathematical Modelling and Analysis
Pulsatile flow
Casson model
Two-layer model
Time-dependent stenosis
title Mathematical analysis of blood flow through an arterial segment with time‐dependent stenosis
title_full Mathematical analysis of blood flow through an arterial segment with time‐dependent stenosis
title_fullStr Mathematical analysis of blood flow through an arterial segment with time‐dependent stenosis
title_full_unstemmed Mathematical analysis of blood flow through an arterial segment with time‐dependent stenosis
title_short Mathematical analysis of blood flow through an arterial segment with time‐dependent stenosis
title_sort mathematical analysis of blood flow through an arterial segment with time dependent stenosis
topic Pulsatile flow
Casson model
Two-layer model
Time-dependent stenosis
url https://journals.vgtu.lt/index.php/MMA/article/view/7026
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