Learning from Nature: Bioinspired Chlorin-Based Photosensitizers Immobilized on Carbon Materials for Combined Photodynamic and Photothermal Therapy
Chlorophylls, which are chlorin-type photosensitizers, are known as the key building blocks of nature and are fundamental for solar energy metabolism during the photosynthesis process. In this regard, the utilization of bioinspired chlorin analogs as photosensitizers for photodynamic therapy constit...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-10-01
|
| Series: | Biomimetics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2313-7673/5/4/53 |
| _version_ | 1797551027913752576 |
|---|---|
| author | Lucas D. Dias Ivan S. Mfouo-Tynga |
| author_facet | Lucas D. Dias Ivan S. Mfouo-Tynga |
| author_sort | Lucas D. Dias |
| collection | DOAJ |
| description | Chlorophylls, which are chlorin-type photosensitizers, are known as the key building blocks of nature and are fundamental for solar energy metabolism during the photosynthesis process. In this regard, the utilization of bioinspired chlorin analogs as photosensitizers for photodynamic therapy constitutes an evolutionary topic of research. Moreover, carbon nanomaterials have been widely applied in photodynamic therapy protocols due to their optical characteristics, good biocompatibility, and tunable systematic toxicity. Herein, we review the literature related to the applications of chlorin-based photosensitizers that were functionalized onto carbon nanomaterials for photodynamic and photothermal therapies against cancer. Rather than a comprehensive review, we intended to highlight the most important and illustrative examples over the last 10 years. |
| first_indexed | 2024-03-10T15:38:55Z |
| format | Article |
| id | doaj.art-d186dd619fa84f55aef69a67d64035c2 |
| institution | Directory Open Access Journal |
| issn | 2313-7673 |
| language | English |
| last_indexed | 2024-03-10T15:38:55Z |
| publishDate | 2020-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomimetics |
| spelling | doaj.art-d186dd619fa84f55aef69a67d64035c22023-11-20T17:00:44ZengMDPI AGBiomimetics2313-76732020-10-01545310.3390/biomimetics5040053Learning from Nature: Bioinspired Chlorin-Based Photosensitizers Immobilized on Carbon Materials for Combined Photodynamic and Photothermal TherapyLucas D. Dias0Ivan S. Mfouo-Tynga1São Carlos Institute of Physics, University of São Paulo, São Carlos 13566-590, BrazilSão Carlos Institute of Physics, University of São Paulo, São Carlos 13566-590, BrazilChlorophylls, which are chlorin-type photosensitizers, are known as the key building blocks of nature and are fundamental for solar energy metabolism during the photosynthesis process. In this regard, the utilization of bioinspired chlorin analogs as photosensitizers for photodynamic therapy constitutes an evolutionary topic of research. Moreover, carbon nanomaterials have been widely applied in photodynamic therapy protocols due to their optical characteristics, good biocompatibility, and tunable systematic toxicity. Herein, we review the literature related to the applications of chlorin-based photosensitizers that were functionalized onto carbon nanomaterials for photodynamic and photothermal therapies against cancer. Rather than a comprehensive review, we intended to highlight the most important and illustrative examples over the last 10 years.https://www.mdpi.com/2313-7673/5/4/53bioinspired photosensitizercancercarbon nanomaterialchlorinphotodynamic therapyphotothermal therapy |
| spellingShingle | Lucas D. Dias Ivan S. Mfouo-Tynga Learning from Nature: Bioinspired Chlorin-Based Photosensitizers Immobilized on Carbon Materials for Combined Photodynamic and Photothermal Therapy Biomimetics bioinspired photosensitizer cancer carbon nanomaterial chlorin photodynamic therapy photothermal therapy |
| title | Learning from Nature: Bioinspired Chlorin-Based Photosensitizers Immobilized on Carbon Materials for Combined Photodynamic and Photothermal Therapy |
| title_full | Learning from Nature: Bioinspired Chlorin-Based Photosensitizers Immobilized on Carbon Materials for Combined Photodynamic and Photothermal Therapy |
| title_fullStr | Learning from Nature: Bioinspired Chlorin-Based Photosensitizers Immobilized on Carbon Materials for Combined Photodynamic and Photothermal Therapy |
| title_full_unstemmed | Learning from Nature: Bioinspired Chlorin-Based Photosensitizers Immobilized on Carbon Materials for Combined Photodynamic and Photothermal Therapy |
| title_short | Learning from Nature: Bioinspired Chlorin-Based Photosensitizers Immobilized on Carbon Materials for Combined Photodynamic and Photothermal Therapy |
| title_sort | learning from nature bioinspired chlorin based photosensitizers immobilized on carbon materials for combined photodynamic and photothermal therapy |
| topic | bioinspired photosensitizer cancer carbon nanomaterial chlorin photodynamic therapy photothermal therapy |
| url | https://www.mdpi.com/2313-7673/5/4/53 |
| work_keys_str_mv | AT lucasddias learningfromnaturebioinspiredchlorinbasedphotosensitizersimmobilizedoncarbonmaterialsforcombinedphotodynamicandphotothermaltherapy AT ivansmfouotynga learningfromnaturebioinspiredchlorinbasedphotosensitizersimmobilizedoncarbonmaterialsforcombinedphotodynamicandphotothermaltherapy |