Cinobufagin alleviates lipopolysaccharide-induced acute lung injury by regulating autophagy through activation of the p53/mTOR pathway
Acute lung injury (ALI) is a severe clinical disorder characterized by dysregulated inflammatory responses, leading to high rates of morbidity and mortality. Cinobufagin, a primary component isolated from cinobufotalin, exerts strong anticancer effects. However, there are few reports on its role in...
Main Authors: | Cheng Wang, Xianghuang Mei, Yanrong Wu, Yuting Yang, Zhenguo Zeng |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-11-01
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Series: | Frontiers in Pharmacology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2022.994625/full |
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