Radiologic patterns of distant organ metastasis in advanced breast cancer patients: Prospective review of computed tomography images
Abstract Background Breast cancer (BC) metastases to the abdomen and pelvis affect the liver, mesentery, retroperitoneum, peritoneum, bladder, kidney, ovary, and uterus. The study documented the radiological pattern and features of the chest, bone, abdominal and pelvic (AP) metastases among advanced...
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| Format: | Article |
| Language: | English |
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Wiley
2024-02-01
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| Series: | Cancer Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/cnr2.1988 |
| _version_ | 1797292575236816896 |
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| author | Bashiru Babatunde Jimah Emmanuella Amoako Emmanuel Owusu Ofori Patrick Kafui Akakpo Luke Adagrah Aniakwo Kofi Ulzen‐Appiah Emmanuel Gustav Imbeah Martin Tangnaa Morna Patience Koggoh Harry Akligoh Randy Tackie Aida Manu Lily Paemka Benjamin Dabo Sarkodie Asare Kweku Offei David Hutchful Joyce Ngoi Yaw Bediako Ganiyu Adebisi Rahman |
| author_facet | Bashiru Babatunde Jimah Emmanuella Amoako Emmanuel Owusu Ofori Patrick Kafui Akakpo Luke Adagrah Aniakwo Kofi Ulzen‐Appiah Emmanuel Gustav Imbeah Martin Tangnaa Morna Patience Koggoh Harry Akligoh Randy Tackie Aida Manu Lily Paemka Benjamin Dabo Sarkodie Asare Kweku Offei David Hutchful Joyce Ngoi Yaw Bediako Ganiyu Adebisi Rahman |
| author_sort | Bashiru Babatunde Jimah |
| collection | DOAJ |
| description | Abstract Background Breast cancer (BC) metastases to the abdomen and pelvis affect the liver, mesentery, retroperitoneum, peritoneum, bladder, kidney, ovary, and uterus. The study documented the radiological pattern and features of the chest, bone, abdominal and pelvic (AP) metastases among advanced BC patients. Aim The aim is to document the radiological pattern and features of breast cancer metastasis in the chest, abdomen, pelvis and bones. Materials and Results Chest, abdominal, and pelvic computed tomography scan images of 36 patients with advanced BC were collated from Cape Coast Teaching Hospital and RAAJ Diagnostics. The images were prospectively assessed for metastasis to the organs of the chest, AP soft tissues, and bones. Radiologic features of metastasis of the lungs, liver, lymph nodes (LNs), and bones were documented. Patients' demographics, clinical data, and histopathology reports were also collected. The data were captured using UVOSYO and exported to Microsoft Excel templates. The data obtained were descriptively analyzed. Only 2.8% of BCs exhibited metaplastic BC, whereas 97.2% had invasive ductal BC. Triple‐negative cases were 55.6%. Of 36 patients, 31 (86.1%), 21 (58.3%), and 14(38.8%) were diagnosed of chest, AP, and bone tissues metastasis, respectively. LN involvement was reported in 26 (72.2%) patients. Majority, 21 (58.3%) were diagnosed of multiple sites metastasis with 15 (41.7%) showing single site. Lungs (77.4%, 24/31) and liver (47.6%, 10/21) were the most affected distant organs. Most bone metastases were lytic lesions (92.9%, 13/14) with the vertebrae (85.7%, 12/14) been the most affected. Conclusion According to the study, advanced BC patients have a higher‐than‐average radiologic incidence of lung, liver, bone, and LN metastases. |
| first_indexed | 2024-03-07T19:58:26Z |
| format | Article |
| id | doaj.art-d18bfde0e2f44a0c9be0195c4949cf99 |
| institution | Directory Open Access Journal |
| issn | 2573-8348 |
| language | English |
| last_indexed | 2024-03-07T19:58:26Z |
| publishDate | 2024-02-01 |
| publisher | Wiley |
| record_format | Article |
| series | Cancer Reports |
| spelling | doaj.art-d18bfde0e2f44a0c9be0195c4949cf992024-02-28T13:54:58ZengWileyCancer Reports2573-83482024-02-0172n/an/a10.1002/cnr2.1988Radiologic patterns of distant organ metastasis in advanced breast cancer patients: Prospective review of computed tomography imagesBashiru Babatunde Jimah0Emmanuella Amoako1Emmanuel Owusu Ofori2Patrick Kafui Akakpo3Luke Adagrah Aniakwo4Kofi Ulzen‐Appiah5Emmanuel Gustav Imbeah6Martin Tangnaa Morna7Patience Koggoh8Harry Akligoh9Randy Tackie10Aida Manu11Lily Paemka12Benjamin Dabo Sarkodie13Asare Kweku Offei14David Hutchful15Joyce Ngoi16Yaw Bediako17Ganiyu Adebisi Rahman18Department of Medical Imaging University of Cape Coast Cape Coast GhanaYemaachi Biotech Accra GhanaDepartment of Surgery Cape Coast Teaching Hospital Cape Coast GhanaDepartment of Pathology University of Cape Coast Cape Coast GhanaDepartment of Surgery Cape Coast Teaching Hospital Cape Coast GhanaDepartment of Pathology Cape Coast Teaching Hospital Cape Coast GhanaACT Pathology Services Cape Coast GhanaDepartment of Surgery University of Cape Coast Cape Coast GhanaDepartment of Surgery Cape Coast Teaching Hospital Cape Coast GhanaYemaachi Biotech Accra GhanaYemaachi Biotech Accra GhanaYemaachi Biotech Accra GhanaYemaachi Biotech Accra GhanaDepartment of Radiology, School of Medicine and Dentistry University of Ghana Accra GhanaDepartment of Surgery Korle Bu Teaching Hospital Accra GhanaYemaachi Biotech Accra GhanaYemaachi Biotech Accra GhanaYemaachi Biotech Accra GhanaDepartment of Surgery University of Cape Coast Cape Coast GhanaAbstract Background Breast cancer (BC) metastases to the abdomen and pelvis affect the liver, mesentery, retroperitoneum, peritoneum, bladder, kidney, ovary, and uterus. The study documented the radiological pattern and features of the chest, bone, abdominal and pelvic (AP) metastases among advanced BC patients. Aim The aim is to document the radiological pattern and features of breast cancer metastasis in the chest, abdomen, pelvis and bones. Materials and Results Chest, abdominal, and pelvic computed tomography scan images of 36 patients with advanced BC were collated from Cape Coast Teaching Hospital and RAAJ Diagnostics. The images were prospectively assessed for metastasis to the organs of the chest, AP soft tissues, and bones. Radiologic features of metastasis of the lungs, liver, lymph nodes (LNs), and bones were documented. Patients' demographics, clinical data, and histopathology reports were also collected. The data were captured using UVOSYO and exported to Microsoft Excel templates. The data obtained were descriptively analyzed. Only 2.8% of BCs exhibited metaplastic BC, whereas 97.2% had invasive ductal BC. Triple‐negative cases were 55.6%. Of 36 patients, 31 (86.1%), 21 (58.3%), and 14(38.8%) were diagnosed of chest, AP, and bone tissues metastasis, respectively. LN involvement was reported in 26 (72.2%) patients. Majority, 21 (58.3%) were diagnosed of multiple sites metastasis with 15 (41.7%) showing single site. Lungs (77.4%, 24/31) and liver (47.6%, 10/21) were the most affected distant organs. Most bone metastases were lytic lesions (92.9%, 13/14) with the vertebrae (85.7%, 12/14) been the most affected. Conclusion According to the study, advanced BC patients have a higher‐than‐average radiologic incidence of lung, liver, bone, and LN metastases.https://doi.org/10.1002/cnr2.1988abdomen and pelvisbreast cancercomputer tomographyliver metastasismetastasisradiology |
| spellingShingle | Bashiru Babatunde Jimah Emmanuella Amoako Emmanuel Owusu Ofori Patrick Kafui Akakpo Luke Adagrah Aniakwo Kofi Ulzen‐Appiah Emmanuel Gustav Imbeah Martin Tangnaa Morna Patience Koggoh Harry Akligoh Randy Tackie Aida Manu Lily Paemka Benjamin Dabo Sarkodie Asare Kweku Offei David Hutchful Joyce Ngoi Yaw Bediako Ganiyu Adebisi Rahman Radiologic patterns of distant organ metastasis in advanced breast cancer patients: Prospective review of computed tomography images Cancer Reports abdomen and pelvis breast cancer computer tomography liver metastasis metastasis radiology |
| title | Radiologic patterns of distant organ metastasis in advanced breast cancer patients: Prospective review of computed tomography images |
| title_full | Radiologic patterns of distant organ metastasis in advanced breast cancer patients: Prospective review of computed tomography images |
| title_fullStr | Radiologic patterns of distant organ metastasis in advanced breast cancer patients: Prospective review of computed tomography images |
| title_full_unstemmed | Radiologic patterns of distant organ metastasis in advanced breast cancer patients: Prospective review of computed tomography images |
| title_short | Radiologic patterns of distant organ metastasis in advanced breast cancer patients: Prospective review of computed tomography images |
| title_sort | radiologic patterns of distant organ metastasis in advanced breast cancer patients prospective review of computed tomography images |
| topic | abdomen and pelvis breast cancer computer tomography liver metastasis metastasis radiology |
| url | https://doi.org/10.1002/cnr2.1988 |
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