Variation in the X-linked EFHC2 gene is associated with social cognitive abilities in males.

Variation in the X-linked EFHC2 gene is associated with social cognitive abilities in males.

Females outperform males on many social cognitive tasks. X-linked genes may contribute to this sex difference. Males possess one X chromosome, while females possess two X chromosomes. Functional variations in X-linked genes are therefore likely to impact more on males than females. Previous studies...

Full description

Bibliographic Details
Main Authors:	Carla M Startin, Chiara Fiorentini, Michelle de Haan, David H Skuse
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2015-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC4481314?pdf=render

Similar Items

Susceptibility to Juvenile Myoclonic Epilepsy Associated with the EFHC1 Gene: First Case Report in Turkey
by: Pınar, et al.
Published: (2019-12-01)

EFHC1, implicated in juvenile myoclonic epilepsy, functions at the cilium and synapse to modulate dopamine signaling
by: Catrina M Loucks, et al.
Published: (2019-02-01)

EF-hand domain containing 2 (Efhc2) is crucial for distal segmentation of pronephros in zebrafish
by: Praveen Barrodia, et al.
Published: (2018-10-01)

Epilepsy protein Efhc1/myoclonin1 is expressed in cells with motile cilia but not in neurons or mitotic apparatuses in brain
by: Toshimitsu Suzuki, et al.
Published: (2020-12-01)

Developing an Informant Questionnaire for Cognitive Abilities in Down Syndrome: The Cognitive Scale for Down Syndrome (CS-DS).
by: Carla M Startin, et al.
Published: (2016-01-01)

Comparison of Receptive Verbal Abilities Assessed Using the KBIT-2 and BPVS3 in Adults With Down Syndrome
by: Carla M. Startin, et al.
Published: (2019-01-01)

The LonDownS adult cognitive assessment to study cognitive abilities and decline in Down syndrome [version 1; referees: 2 approved]
by: Carla M. Startin, et al.
Published: (2016-11-01)

Comparison of receptive verbal abilities assessed using the KBIT-2 and BPVS3 in adults with down syndrome
by: Startin, Carla M., et al.
Published: (2019)

Evidence from Turner's syndrome of an imprinted X-linked locus affecting cognitive function
by: Skuse, D, et al.
Published: (1997)

Health comorbidities and cognitive abilities across the lifespan in Down syndrome
by: Carla M. Startin, et al.
Published: (2020-01-01)

Overall intact cognitive function in male X-linked adrenoleukodystrophy adults with normal MRI
by: Noortje J. M. L. Buermans, et al.
Published: (2019-09-01)

Genetic copy number variation and general cognitive ability.
by: Andrew K MacLeod, et al.
Published: (2012-01-01)

Assessing general cognitive and adaptive abilities in adults with Down syndrome: a systematic review
by: Sarah Hamburg, et al.
Published: (2019-08-01)

Effect of neonatal dexamethasone treatment on cognitive abilities of adult male mice and gene expression in the hypothalamus
by: N. P. Bondar, et al.
Published: (2019-07-01)

Elevated HDL Levels Linked to Poorer Cognitive Ability in Females With Parkinson’s Disease
by: Megan C. Bakeberg, et al.
Published: (2021-06-01)

The link between cognitive abilities and risk preference depends on measurement
by: Sebastian Olschewski, et al.
Published: (2023-11-01)

Validating the Cognitive Scale for Down Syndrome (CS-DS) to Detect Longitudinal Cognitive Decline in Adults With Down Syndrome
by: Carla M. Startin, et al.
Published: (2019-04-01)

The Two-Systems Account of Theory of Mind: Testing the Links to Social- Perceptual and Cognitive Abilities
by: Bozana Meinhardt-Injac, et al.
Published: (2018-01-01)

Prune belly syndrome in surviving males can be caused by Hemizygous missense mutations in the X-linked Filamin A gene
by: Nida S. Iqbal, et al.
Published: (2020-02-01)

X-linked gene transcription patterns in female and male in vivo, in vitro and cloned porcine individual blastocysts.
by: Chi-Hun Park, et al.
Published: (2012-01-01)

Generalist genes and cognitive abilities in Chinese twins.
by: Chow, B, et al.
Published: (2013)

Multimodal neuroimaging markers of variation in cognitive ability in older HIV+ men.
by: Ana Lucia Fernandez Cruz, et al.
Published: (2021-01-01)

Distinct components of cardiovascular health are linked with age-related differences in cognitive abilities
by: Deborah L. O. King, et al.
Published: (2023-01-01)

Changes in retinal sensitivity associated with cotoretigene toliparvovec in X-linked retinitis pigmentosa with RPGR gene variations
by: von Krusenstiern, L, et al.
Published: (2023)

Characterization of carrier females and affected males with X-linked recessive nephrolithiasis.
by: Reinhart, S, et al.
Published: (1995)

The effect of X-linked dosage compensation on complex trait variation
by: Julia Sidorenko, et al.
Published: (2019-07-01)

The contribution of X-linked coding variation to severe developmental disorders
by: Hilary C. Martin, et al.
Published: (2021-01-01)

X-linked palindromic gene families 4930567H17Rik and Mageb5 are dispensable for male mouse fertility
by: Evan R. Stark-Dykema, et al.
Published: (2022-05-01)

P014: Multiple cases of mosaic X-linked adrenoleukodystrophy in males identified through newborn screening
by: Alexandra Keefe, et al.
Published: (2024-01-01)

FURTHER LOCALIZATION OF THE GENE FOR X-LINKED HYPOPHOSPHATEMIA
by: Read, A, et al.
Published: (1987)

LOCALIZATION OF THE X-LINKED HYPOPHOSPHATEMIC RICKETS GENE
by: Thakker, R, et al.
Published: (1986)

Variation in phenotype, parasite load and male competitive ability across a cryptic hybrid zone.
by: Devi Stuart-Fox, et al.
Published: (2009-05-01)

Dosage-Dependent Expression Variation Suppressed on the Drosophila Male X Chromosome
by: Hangnoh Lee, et al.
Published: (2018-02-01)

Paternal age and general cognitive ability-a cross sectional study of Danish male conscripts.
by: John McGrath, et al.
Published: (2013-01-01)

Exploring the Link Between Cognitive Abilities and Speech Recognition in the Elderly Under Different Listening Conditions
by: Theresa Nuesse, et al.
Published: (2018-05-01)

Linking managers’ emotional intelligence, cognitive ability and firm performance: Insights from Vietnamese firms
by: Huong Trang Kim
Published: (2020-01-01)

Differences in Cognitive-Perceptual Factors Arising From Variations in Self-Professed Paranormal Ability
by: Kenneth Graham Drinkwater, et al.
Published: (2021-06-01)

A Missense Variation in the KDM5C Gene Associated with X-Linked Intellectual Disability, Growth Failure, and Epilepsy
by: Jin A Chung, et al.
Published: (2023-01-01)

Dosage Compensation of X-Linked Muller Element F Genes but Not X-Linked Transgenes in the Australian Sheep Blowfly.
by: Rebecca J Linger, et al.
Published: (2015-01-01)

Open-Loop Neuroadaptive System for Enhancing Student’s Cognitive Abilities in Learning
by: Vadim V. Grubov, et al.
Published: (2024-01-01)