Case Report: Tuberculosis lymphadenitis with systemic lupus erythematosus in a young woman: a case report [version 2; peer review: 2 approved, 1 not approved]
Background: Tuberculosis is a chronic infectious disease and can be categorised into pulmonary TB and extra-pulmonary TB based on its spread. TB lymphadenitis is one of the extra-pulmonary TB diseases. Patients with a weakened immune system in systemic lupus erythematosus (SLE) have an increased inc...
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| Format: | Article |
| Language: | English |
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F1000 Research Ltd
2023-10-01
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| Series: | F1000Research |
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| Online Access: | https://f1000research.com/articles/12-763/v2 |
| _version_ | 1797629018186448896 |
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| author | Samantha Geraldine Dewi Behtri Yanifitri Wilia Aprilisa Utami Yunita Arliny |
| author_facet | Samantha Geraldine Dewi Behtri Yanifitri Wilia Aprilisa Utami Yunita Arliny |
| author_sort | Samantha Geraldine |
| collection | DOAJ |
| description | Background: Tuberculosis is a chronic infectious disease and can be categorised into pulmonary TB and extra-pulmonary TB based on its spread. TB lymphadenitis is one of the extra-pulmonary TB diseases. Patients with a weakened immune system in systemic lupus erythematosus (SLE) have an increased incidence of TB. Case: Here we present a case report of a 21-year-old female patient with SLE diagnosed with tuberculous lymphadenitis at dr. Zainoel Abidin Hospital, Banda Aceh, Indonesia. The patient complained of a lump in the right neck 4 months ago with a diameter of 4 cm, accompanied by fever, decreased appetite, and weight loss. Other than that, the patient also experiences joint pain, hair loss and sun sensitivity since 12 months ago. Chest radiography showed no abnormalities, and fine-needle aspiration biopsy results confirmed tuberculous lymphadenitis. Antinuclear antibody test was borderline. The patient had been taking steroids and hydroxychloroquine for the past 10 months. Currently, the patient is taking the advanced phase of antituberculosis drugs FDC. After undergoing the intensive phase of antituberculosis drugs, the submandibular lump got smaller to a diameter of 2 cm. Conclusion: TB lymphadenitis is a rare case but can occur in conditions of decreased immunity like SLE. It involves some of the immune disorders caused by the long-term use of immunosuppressive therapy. |
| first_indexed | 2024-03-11T10:47:29Z |
| format | Article |
| id | doaj.art-d18ce2ab3f874d779c8b1102b346ea38 |
| institution | Directory Open Access Journal |
| issn | 2046-1402 |
| language | English |
| last_indexed | 2024-03-11T10:47:29Z |
| publishDate | 2023-10-01 |
| publisher | F1000 Research Ltd |
| record_format | Article |
| series | F1000Research |
| spelling | doaj.art-d18ce2ab3f874d779c8b1102b346ea382023-11-14T01:00:03ZengF1000 Research LtdF1000Research2046-14022023-10-0112157467Case Report: Tuberculosis lymphadenitis with systemic lupus erythematosus in a young woman: a case report [version 2; peer review: 2 approved, 1 not approved]Samantha Geraldine0Dewi Behtri Yanifitri1Wilia Aprilisa Utami2Yunita Arliny3https://orcid.org/0000-0003-1950-4025Faculty of Medicine, Universitas Sebelas Maret, Surakarta, Central Java, IndonesiaPulmonology and Respiratory Medicine, Rumah Sakit Umum Daerah Dr Zainoel Abidin, Banda Aceh, Aceh, IndonesiaPulmonology and Respiratory Medicine, Rumah Sakit Umum Daerah Dr Zainoel Abidin, Banda Aceh, Aceh, IndonesiaPulmonology and Respiratory Medicine, Rumah Sakit Umum Daerah Dr Zainoel Abidin, Banda Aceh, Aceh, IndonesiaBackground: Tuberculosis is a chronic infectious disease and can be categorised into pulmonary TB and extra-pulmonary TB based on its spread. TB lymphadenitis is one of the extra-pulmonary TB diseases. Patients with a weakened immune system in systemic lupus erythematosus (SLE) have an increased incidence of TB. Case: Here we present a case report of a 21-year-old female patient with SLE diagnosed with tuberculous lymphadenitis at dr. Zainoel Abidin Hospital, Banda Aceh, Indonesia. The patient complained of a lump in the right neck 4 months ago with a diameter of 4 cm, accompanied by fever, decreased appetite, and weight loss. Other than that, the patient also experiences joint pain, hair loss and sun sensitivity since 12 months ago. Chest radiography showed no abnormalities, and fine-needle aspiration biopsy results confirmed tuberculous lymphadenitis. Antinuclear antibody test was borderline. The patient had been taking steroids and hydroxychloroquine for the past 10 months. Currently, the patient is taking the advanced phase of antituberculosis drugs FDC. After undergoing the intensive phase of antituberculosis drugs, the submandibular lump got smaller to a diameter of 2 cm. Conclusion: TB lymphadenitis is a rare case but can occur in conditions of decreased immunity like SLE. It involves some of the immune disorders caused by the long-term use of immunosuppressive therapy.https://f1000research.com/articles/12-763/v2Tuberculosis TB lymphadenitis Tuberculous lymphadenitis Systemic Lupus Erythematosus SLEeng |
| spellingShingle | Samantha Geraldine Dewi Behtri Yanifitri Wilia Aprilisa Utami Yunita Arliny Case Report: Tuberculosis lymphadenitis with systemic lupus erythematosus in a young woman: a case report [version 2; peer review: 2 approved, 1 not approved] F1000Research Tuberculosis TB lymphadenitis Tuberculous lymphadenitis Systemic Lupus Erythematosus SLE eng |
| title | Case Report: Tuberculosis lymphadenitis with systemic lupus erythematosus in a young woman: a case report [version 2; peer review: 2 approved, 1 not approved] |
| title_full | Case Report: Tuberculosis lymphadenitis with systemic lupus erythematosus in a young woman: a case report [version 2; peer review: 2 approved, 1 not approved] |
| title_fullStr | Case Report: Tuberculosis lymphadenitis with systemic lupus erythematosus in a young woman: a case report [version 2; peer review: 2 approved, 1 not approved] |
| title_full_unstemmed | Case Report: Tuberculosis lymphadenitis with systemic lupus erythematosus in a young woman: a case report [version 2; peer review: 2 approved, 1 not approved] |
| title_short | Case Report: Tuberculosis lymphadenitis with systemic lupus erythematosus in a young woman: a case report [version 2; peer review: 2 approved, 1 not approved] |
| title_sort | case report tuberculosis lymphadenitis with systemic lupus erythematosus in a young woman a case report version 2 peer review 2 approved 1 not approved |
| topic | Tuberculosis TB lymphadenitis Tuberculous lymphadenitis Systemic Lupus Erythematosus SLE eng |
| url | https://f1000research.com/articles/12-763/v2 |
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