Exploring the functional role of tRF-39-8HM2OSRNLNKSEKH9 in hepatocellular carcinoma

Exploring the functional role of tRF-39-8HM2OSRNLNKSEKH9 in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is associated with high morbidity and mortality globally. tRNA-derived small RNAs (tsRNAs) have emerged as potential targets for cancer treatment. However, the specific impact of tsRNAs on HCC remains undiscovered. In this study, we aimed to investigate the biological...

Full description

Bibliographic Details
Main Authors:	Tianxin Xu, Jie Yuan, Fei Song, Nannan Zhang, Cheng Gao, Zhong Chen
Format:	Article
Language:	English
Published:	Elsevier 2024-03-01
Series:	Heliyon
Subjects:	Hepatocellular carcinoma tRNA-derived small RNAs Oncogene Proliferation Migration Invasion
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405844024031840

Similar Items

Effect of tRF-Pro-CGG on the biological behavior of mouse pancreatic cancer cells and its molecular mechanism
by: FU Qingsheng, JIN Lei, ZHANG Xudong, XU Yingchen, ZHU Chunfu, QIN Xihu, WU Baoqiang
Published: (2023-03-01)

Transfer RNA-derived small RNA tRF-Glu-CTC attenuates neointimal formation via inhibition of fibromodulin
by: Qi-Lan Jiang, et al.
Published: (2024-01-01)

Influence of Maternal BLV Infection on miRNA and tRF Expression in Calves
by: Anna K. Goldkamp, et al.
Published: (2023-11-01)

tRF-3013b inhibits gallbladder cancer proliferation by targeting TPRG1L
by: Lu Zou, et al.
Published: (2022-11-01)

tRNA<sup>GlyGCC</sup>-Derived Internal Fragment (i-tRF-GlyGCC) in Ovarian Cancer Treatment Outcome and Progression
by: Konstantina Panoutsopoulou, et al.
Published: (2021-12-01)

A Novel tRNA-Derived Fragment, tRF<sup>GlnCTG</sup>, Regulates Angiogenesis by Targeting Antxr1 mRNA
by: Qiuyang Chen, et al.
Published: (2023-09-01)

SP1/RNASEH2A accelerates the development of hepatocellular carcinoma by regulating EMT
by: Yunhe Hao, et al.
Published: (2023-08-01)

Plasma tRF-16-79MP9PD and tRF-28-OB1690PQR304 as potential biomarkers for 4- to 7-year-old children with obstructive sleep apnea-hypopnea syndrome
by: Junhua Wu, et al.
Published: (2023-05-01)

CircMMP11 as a prognostic biomarker mediates miR-361-3p/HMGB1 axis to accelerate malignant progression of hepatocellular carcinoma
by: Zou Qiong, et al.
Published: (2023-11-01)

Ozonated Water Inhibits Hepatocellular Carcinoma Invasion and Metastasis by Regulating the HMGB1/NF-κB/STAT3 Signaling Pathway
by: Tang S, et al.
Published: (2023-02-01)

The potential of tRF-21-U0EZY9X1B plasmatic level as a biomarker of children with obstructive sleep apnea-hypopnea syndrome
by: Yanbo Lu, et al.
Published: (2023-04-01)

Evaluation of the serum tRNA-derived fragment tRF-5022B as a potential biomarker for the diagnosis of osteoarthritis
by: Yingchen Ni, et al.
Published: (2023-10-01)

An Imbalance in Histone Modifiers Induces tRNA-Cys-GCA Overexpression and tRF-27 Accumulation by Attenuating Promoter H3K27me3 in Primary Trastuzumab-Resistant Breast Cancer
by: Ningjun Duan, et al.
Published: (2024-03-01)

Characteristics of Transfer RNA-Derived Fragments Expressed during Human Renal Cell Development: The Role of Dicer in tRF Biogenesis
by: Marek Kazimierczyk, et al.
Published: (2022-03-01)

LINC00844 promotes proliferation and migration of hepatocellular carcinoma by regulating NDRG1 expression
by: Wei Zhou, et al.
Published: (2020-01-01)

Exosome-Transmitted tRF-16-K8J7K1B Promotes Tamoxifen Resistance by Reducing Drug-Induced Cell Apoptosis in Breast Cancer
by: Chunxiao Sun, et al.
Published: (2023-01-01)

tRF-Val-CAC-016 modulates the transduction of CACNA1d-mediated MAPK signaling pathways to suppress the proliferation of gastric carcinoma
by: Weiguo Xu, et al.
Published: (2022-05-01)

tRNA-Derived Fragments (tRFs) in Bladder Cancer: Increased 5′-tRF-LysCTT Results in Disease Early Progression and Patients’ Poor Treatment Outcome
by: Maria-Alexandra Papadimitriou, et al.
Published: (2020-12-01)

Expression and Role of Integrin β-like 1 in Hepatocellular Carcinoma
by: LIN Liyan, et al.
Published: (2022-12-01)

Effect of overexpression of forkhead box B2 on proliferation, invasion and migration of hepatocellular carcinoma cells
by: Liang Junhui, Chen Zerui, Peng Shuming, Chen Shanjia, Shu Bairong
Published: (2022-01-01)

The upregulation of stromal antigen 3 expression suppresses the phenotypic hallmarks of hepatocellular carcinoma through the Smad3-CDK4/CDK6-cyclin D1 and CXCR4/RhoA pathways
by: Menglin Zhao, et al.
Published: (2022-08-01)

ALKBH5 promotes hepatocellular carcinoma cell proliferation, migration and invasion by regulating TTI1 expression
by: Qimeng Chang, et al.
Published: (2024-03-01)

MicroRNA‐383 inhibits proliferation, migration, and invasion in hepatocellular carcinoma cells by targeting PHF8
by: Yan Cheng, et al.
Published: (2020-08-01)

Daucosterol Inhibits the Proliferation, Migration, and Invasion of Hepatocellular Carcinoma Cells via Wnt/β-Catenin Signaling
by: Junquan Zeng, et al.
Published: (2017-06-01)

m<sup>5</sup>U54 tRNA Hypomodification by Lack of TRMT2A Drives the Generation of tRNA-Derived Small RNAs
by: Marisa Pereira, et al.
Published: (2021-03-01)

The Importance of AGO 1 and 4 in Post-Transcriptional Gene Regulatory Function of tRF5-GluCTC, an Respiratory Syncytial Virus-Induced tRNA-Derived RNA Fragment
by: Eun-Jin Choi, et al.
Published: (2020-11-01)

Small Noncoding RNAs in Knee Osteoarthritis: The Role of MicroRNAs and tRNA-Derived Fragments
by: Julian Zacharjasz, et al.
Published: (2021-05-01)

tRF-1001: A potential therapeutic target for ocular neovascular diseases
by: Pradeep Reddy Cingaram
Published: (2023-03-01)

Advances in the Study of circRNAs in Hematological Malignancies
by: Jingyi Du, et al.
Published: (2022-06-01)

The Role of tRNA-Centered Translational Regulatory Mechanisms in Cancer
by: Yuanjian Shi, et al.
Published: (2023-12-01)

5’ tRNA halves may function as immune signaling molecules
by: Joseph Mohsen Dhahbi, et al.
Published: (2015-02-01)

A novel tRNA-derived fragment tRF-3022b modulates cell apoptosis and M2 macrophage polarization via binding to cytokines in colorectal cancer
by: Sicheng Lu, et al.
Published: (2022-12-01)

The widespread occurrence of tRNA‐derived fragments in Saccharomyces cerevisiae
by: Kamilla Bąkowska‐Żywicka, et al.
Published: (2016-12-01)

Combination of Vitamin C and Lenvatinib potentiates antitumor effects in hepatocellular carcinoma cells in vitro
by: Xinyue Wang, et al.
Published: (2023-01-01)

FBXL19 promotes malignant behaviours by activating MAPK signalling and negatively correlates with prognosis in hepatocellular carcinoma
by: Min Xun, et al.
Published: (2023-11-01)

The Expression Pattern of tRNA-Derived Small RNAs in Adult <i>Drosophila</i> and the Function of <i>tRF-Trp-CCA-014</i>-<i>H3C4</i> Network Analysis
by: Deying Yang, et al.
Published: (2023-03-01)

The role of GPS2 in regulating proliferation, migration and invasion of hepatocellular carcinoma cell line MHCC-97H
by: LIU Aixia, ZHANG Hao, SUN Jie, YANG Lihua, ZHAO Xiaotao
Published: (2023-12-01)

<i>SQSTM1/p62</i> Knockout by Using the CRISPR/Cas9 System Inhibits Migration and Invasion of Hepatocellular Carcinoma
by: Jinghua Lu, et al.
Published: (2023-04-01)

Metazoan tsRNAs: Biogenesis, Evolution and Regulatory Functions
by: Shengqian Dou, et al.
Published: (2019-02-01)

HOX Antisense lincRNA HOXA-AS2 Promotes Tumorigenesis of Hepatocellular Carcinoma
by: Fuqiang Wang, et al.
Published: (2016-11-01)