Prostatic stromal sarcoma in an adolescent: the role of chemotherapy
Prostatic stromal sarcoma (PSS) is a rare tumor that normally occurs in adult age. Its management relies mainly on surgery. We report the first case of PSS occurring in an adolescent. There was evidence of a good response to chemotherapy including ifosfamide, doxorubicin, vincristine and actinomycin...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2014-12-01
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| Series: | Rare Tumors |
| Subjects: | |
| Online Access: | http://www.pagepress.org/journals/index.php/rt/article/view/5607 |
| _version_ | 1823990837236727808 |
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| author | Elena Cavaliere Rita Alaggio Marco Castagnetti Giovanni Scarzello Gianni Bisogno |
| author_facet | Elena Cavaliere Rita Alaggio Marco Castagnetti Giovanni Scarzello Gianni Bisogno |
| author_sort | Elena Cavaliere |
| collection | DOAJ |
| description | Prostatic stromal sarcoma (PSS) is a rare tumor that normally occurs in adult age. Its management relies mainly on surgery. We report the first case of PSS occurring in an adolescent. There was evidence of a good response to chemotherapy including ifosfamide, doxorubicin, vincristine and actinomycin-D, although the final outcome was dismal. A review of the English literature revealed 14 additional patients with PSS treated with chemotherapy: tumor shrinkage was reported in 4 of the 6 evaluable patients. Patients with PSS may benefit from the use of chemotherapy in combination with early aggressive local treatment. |
| first_indexed | 2024-12-18T15:45:03Z |
| format | Article |
| id | doaj.art-d18ff7aa38a647a9b0260ea00ebf8780 |
| institution | Directory Open Access Journal |
| issn | 2036-3605 2036-3613 |
| language | English |
| last_indexed | 2024-12-18T15:45:03Z |
| publishDate | 2014-12-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Rare Tumors |
| spelling | doaj.art-d18ff7aa38a647a9b0260ea00ebf87802022-12-21T21:02:44ZengSAGE PublishingRare Tumors2036-36052036-36132014-12-016410.4081/rt.2014.56072992Prostatic stromal sarcoma in an adolescent: the role of chemotherapyElena Cavaliere0Rita Alaggio1Marco Castagnetti2Giovanni Scarzello3Gianni Bisogno4Pediatric Hematology and Oncology Division, Department of Woman’s and Child’s Health, Padova University HospitalPathology Department, Padova University HospitalUrology Department, Padova University HospitalRadiotherapy Department, Istituto Oncologico Veneto-IRCCS, PadovaPediatric Hematology and Oncology Division, Department of Woman’s and Child’s Health, Padova University HospitalProstatic stromal sarcoma (PSS) is a rare tumor that normally occurs in adult age. Its management relies mainly on surgery. We report the first case of PSS occurring in an adolescent. There was evidence of a good response to chemotherapy including ifosfamide, doxorubicin, vincristine and actinomycin-D, although the final outcome was dismal. A review of the English literature revealed 14 additional patients with PSS treated with chemotherapy: tumor shrinkage was reported in 4 of the 6 evaluable patients. Patients with PSS may benefit from the use of chemotherapy in combination with early aggressive local treatment.http://www.pagepress.org/journals/index.php/rt/article/view/5607stromal sarcoma, specialized prostatic stroma, chemotherapy, prostatic neoplasm |
| spellingShingle | Elena Cavaliere Rita Alaggio Marco Castagnetti Giovanni Scarzello Gianni Bisogno Prostatic stromal sarcoma in an adolescent: the role of chemotherapy Rare Tumors stromal sarcoma, specialized prostatic stroma, chemotherapy, prostatic neoplasm |
| title | Prostatic stromal sarcoma in an adolescent: the role of chemotherapy |
| title_full | Prostatic stromal sarcoma in an adolescent: the role of chemotherapy |
| title_fullStr | Prostatic stromal sarcoma in an adolescent: the role of chemotherapy |
| title_full_unstemmed | Prostatic stromal sarcoma in an adolescent: the role of chemotherapy |
| title_short | Prostatic stromal sarcoma in an adolescent: the role of chemotherapy |
| title_sort | prostatic stromal sarcoma in an adolescent the role of chemotherapy |
| topic | stromal sarcoma, specialized prostatic stroma, chemotherapy, prostatic neoplasm |
| url | http://www.pagepress.org/journals/index.php/rt/article/view/5607 |
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