Effect of fruit on glucose control in diabetes mellitus: a meta-analysis of nineteen randomized controlled trials
ObjectiveDiabetes mellitus is a worldwide health problem, and it remains unclarified whether fruit is beneficial in glycemic control. This study aimed to analyze evidence from randomized controlled trials evaluating the effect of fruit consumption on glucose control.MethodsWe searched the PubMed, EM...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-05-01
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| Series: | Frontiers in Endocrinology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2023.1174545/full |
| _version_ | 1797832865356972032 |
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| author | Yu Ren Shuang Sun Yongwei Su Chenfei Ying Hua Luo |
| author_facet | Yu Ren Shuang Sun Yongwei Su Chenfei Ying Hua Luo |
| author_sort | Yu Ren |
| collection | DOAJ |
| description | ObjectiveDiabetes mellitus is a worldwide health problem, and it remains unclarified whether fruit is beneficial in glycemic control. This study aimed to analyze evidence from randomized controlled trials evaluating the effect of fruit consumption on glucose control.MethodsWe searched the PubMed, EMBASE, Ovid, Web of Science, and Cochrane Central Register of Controlled Trials databases from the respective database inception dates to December 30, 2022, to identify randomized controlled trials that evaluated the effects of fruit consumption on glucose control. Two researchers independently screened the studies in accordance with the inclusion and exclusion criteria, and performed the literature quality evaluation and data extraction. RevMan 5.4 software was used to perform the data analysis.ResultsNineteen randomized controlled trials with 888 participants were included. Fruit consumption significantly decreased the fasting blood glucose concentration (MD -8.38, 95% CI -12.34 to -4.43), but it showed no significant difference in the glycosylated hemoglobin (MD -0.17, 95% CI -0.51 to 0.17). Subgroup analyses further suggested that the consumption of both fresh and dried fruit decreased the fasting blood glucose concentration.ConclusionsIncreasing the fruit intake reduced fasting blood glucose concentration. Therefore, we recommend that patients with diabetes eat more fruits while ensuring that their total energy intake remains unchanged. |
| first_indexed | 2024-04-09T14:14:35Z |
| format | Article |
| id | doaj.art-d1929adf2dd74655865ba3646f65c7ad |
| institution | Directory Open Access Journal |
| issn | 1664-2392 |
| language | English |
| last_indexed | 2024-04-09T14:14:35Z |
| publishDate | 2023-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Endocrinology |
| spelling | doaj.art-d1929adf2dd74655865ba3646f65c7ad2023-05-05T15:27:32ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922023-05-011410.3389/fendo.2023.11745451174545Effect of fruit on glucose control in diabetes mellitus: a meta-analysis of nineteen randomized controlled trialsYu Ren0Shuang Sun1Yongwei Su2Chenfei Ying3Hua Luo4Department of Pharmacy, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, ChinaKey Laboratory of Pathobiology, Ministry of Education, Nanomedicine and Translational Research Center, The Third Bethune Hospital of Jilin University, Changchun, Jilin, ChinaDepartment of Orthopedic, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, ChinaDepartment of Orthopedic, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, ChinaDepartment of Orthopedic, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, ChinaObjectiveDiabetes mellitus is a worldwide health problem, and it remains unclarified whether fruit is beneficial in glycemic control. This study aimed to analyze evidence from randomized controlled trials evaluating the effect of fruit consumption on glucose control.MethodsWe searched the PubMed, EMBASE, Ovid, Web of Science, and Cochrane Central Register of Controlled Trials databases from the respective database inception dates to December 30, 2022, to identify randomized controlled trials that evaluated the effects of fruit consumption on glucose control. Two researchers independently screened the studies in accordance with the inclusion and exclusion criteria, and performed the literature quality evaluation and data extraction. RevMan 5.4 software was used to perform the data analysis.ResultsNineteen randomized controlled trials with 888 participants were included. Fruit consumption significantly decreased the fasting blood glucose concentration (MD -8.38, 95% CI -12.34 to -4.43), but it showed no significant difference in the glycosylated hemoglobin (MD -0.17, 95% CI -0.51 to 0.17). Subgroup analyses further suggested that the consumption of both fresh and dried fruit decreased the fasting blood glucose concentration.ConclusionsIncreasing the fruit intake reduced fasting blood glucose concentration. Therefore, we recommend that patients with diabetes eat more fruits while ensuring that their total energy intake remains unchanged.https://www.frontiersin.org/articles/10.3389/fendo.2023.1174545/fullfruitglucosediabetesglycosylated hemoglobinmeta-analaysis |
| spellingShingle | Yu Ren Shuang Sun Yongwei Su Chenfei Ying Hua Luo Effect of fruit on glucose control in diabetes mellitus: a meta-analysis of nineteen randomized controlled trials Frontiers in Endocrinology fruit glucose diabetes glycosylated hemoglobin meta-analaysis |
| title | Effect of fruit on glucose control in diabetes mellitus: a meta-analysis of nineteen randomized controlled trials |
| title_full | Effect of fruit on glucose control in diabetes mellitus: a meta-analysis of nineteen randomized controlled trials |
| title_fullStr | Effect of fruit on glucose control in diabetes mellitus: a meta-analysis of nineteen randomized controlled trials |
| title_full_unstemmed | Effect of fruit on glucose control in diabetes mellitus: a meta-analysis of nineteen randomized controlled trials |
| title_short | Effect of fruit on glucose control in diabetes mellitus: a meta-analysis of nineteen randomized controlled trials |
| title_sort | effect of fruit on glucose control in diabetes mellitus a meta analysis of nineteen randomized controlled trials |
| topic | fruit glucose diabetes glycosylated hemoglobin meta-analaysis |
| url | https://www.frontiersin.org/articles/10.3389/fendo.2023.1174545/full |
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