A functional study of caustic strictures of the esophagus in children

The objective of the present study was to assess esophageal motor function in 21 children (7.5 ± 2.9 years) with caustic strictures. Esophageal manometry was performed using a water-infusion system interfaced with a polygraph and displayed on a computer screen. The data were compared with those obta...

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Main Authors: E.A.L. Da-Costa-Pinto, T.K. Dorsa, A. Altimani, N.A. Andreollo, S.R. Cardoso, D.J. Morais, J.M. Bustorff-Silva
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2004-11-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004001100005
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author E.A.L. Da-Costa-Pinto
T.K. Dorsa
A. Altimani
N.A. Andreollo
S.R. Cardoso
D.J. Morais
J.M. Bustorff-Silva
author_facet E.A.L. Da-Costa-Pinto
T.K. Dorsa
A. Altimani
N.A. Andreollo
S.R. Cardoso
D.J. Morais
J.M. Bustorff-Silva
author_sort E.A.L. Da-Costa-Pinto
collection DOAJ
description The objective of the present study was to assess esophageal motor function in 21 children (7.5 ± 2.9 years) with caustic strictures. Esophageal manometry was performed using a water-infusion system interfaced with a polygraph and displayed on a computer screen. The data were compared with those obtained from 9 healthy children. Radionuclide transit was determined by studying deglutition of a single bolus of 99mTc pertechnetate in 10 ml of water. Non-peristaltic low-amplitude and long-duration waves were the most common findings detected in patients with strictures longer than 20% of esophageal length (N = 11). Compared with the control group, these patients presented lower mean amplitude and longer mean duration of waves (24.4 ± 11.2 vs 97.9 ± 23.7 mmHg, P < 0.05, and 6.7 ± 2.4 vs 1.6 ± 0.1 s, P < 0.05, respectively). Six patients presented low-amplitude waves just below the constricted site. Ten children presented delayed esophageal transit. There was an association between dysphagia and abnormalities on manometry (P = 0.02) and between symptoms and scintigraphy data (P = 0.01). Dysphagia in caustic strictures is due to esophageal motility abnormalities, which are closely related to the scarred segment.
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spelling doaj.art-d194ce1559284baf94a95edcc971cdf42022-12-21T17:33:20ZengAssociação Brasileira de Divulgação CientíficaBrazilian Journal of Medical and Biological Research0100-879X1414-431X2004-11-0137111623163010.1590/S0100-879X2004001100005A functional study of caustic strictures of the esophagus in childrenE.A.L. Da-Costa-PintoT.K. DorsaA. AltimaniN.A. AndreolloS.R. CardosoD.J. MoraisJ.M. Bustorff-SilvaThe objective of the present study was to assess esophageal motor function in 21 children (7.5 ± 2.9 years) with caustic strictures. Esophageal manometry was performed using a water-infusion system interfaced with a polygraph and displayed on a computer screen. The data were compared with those obtained from 9 healthy children. Radionuclide transit was determined by studying deglutition of a single bolus of 99mTc pertechnetate in 10 ml of water. Non-peristaltic low-amplitude and long-duration waves were the most common findings detected in patients with strictures longer than 20% of esophageal length (N = 11). Compared with the control group, these patients presented lower mean amplitude and longer mean duration of waves (24.4 ± 11.2 vs 97.9 ± 23.7 mmHg, P < 0.05, and 6.7 ± 2.4 vs 1.6 ± 0.1 s, P < 0.05, respectively). Six patients presented low-amplitude waves just below the constricted site. Ten children presented delayed esophageal transit. There was an association between dysphagia and abnormalities on manometry (P = 0.02) and between symptoms and scintigraphy data (P = 0.01). Dysphagia in caustic strictures is due to esophageal motility abnormalities, which are closely related to the scarred segment.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004001100005Caustic esophagitisEsophageal dysfunctionManometryEsophageal transit
spellingShingle E.A.L. Da-Costa-Pinto
T.K. Dorsa
A. Altimani
N.A. Andreollo
S.R. Cardoso
D.J. Morais
J.M. Bustorff-Silva
A functional study of caustic strictures of the esophagus in children
Brazilian Journal of Medical and Biological Research
Caustic esophagitis
Esophageal dysfunction
Manometry
Esophageal transit
title A functional study of caustic strictures of the esophagus in children
title_full A functional study of caustic strictures of the esophagus in children
title_fullStr A functional study of caustic strictures of the esophagus in children
title_full_unstemmed A functional study of caustic strictures of the esophagus in children
title_short A functional study of caustic strictures of the esophagus in children
title_sort functional study of caustic strictures of the esophagus in children
topic Caustic esophagitis
Esophageal dysfunction
Manometry
Esophageal transit
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004001100005
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