Vex-seq: high-throughput identification of the impact of genetic variation on pre-mRNA splicing efficiency

Vex-seq: high-throughput identification of the impact of genetic variation on pre-mRNA splicing efficiency

Abstract Understanding the functional impact of genomic variants is a major goal of modern genetics and personalized medicine. Although many synonymous and non-coding variants act through altering the efficiency of pre-mRNA splicing, it is difficult to predict how these variants impact pre-mRNA spli...

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Bibliographic Details
Main Authors:	Scott I. Adamson, Lijun Zhan, Brenton R. Graveley
Format:	Article
Language:	English
Published:	BMC 2018-06-01
Series:	Genome Biology
Online Access:	http://link.springer.com/article/10.1186/s13059-018-1437-x

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