The Effects of Topical Anesthesia With Lidocaine 10% Spray Compared to Trans Tracheal and Glossopharyngeal Nerve Block in Hemodynamic Stability During Awake Intubation: A Randomized Controlled Trial
Hemodynamic changes is of great concern during awake intubation, particularly in patients with underlying medical conditions. As heterogeneities exist in regard to the best anesthesia drugs and techniques, herein, we aimed to investigate the effects of Lidocaine 10% spray compared to trans tracheal...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Tehran University of Medical Sciences
2024-03-01
|
| Series: | Acta Medica Iranica |
| Subjects: | |
| Online Access: | https://acta.tums.ac.ir/index.php/acta/article/view/11021 |
| _version_ | 1797219214480637952 |
|---|---|
| author | Nader Ali Nazemian Yazdi Abolghasem Yoosefi |
| author_facet | Nader Ali Nazemian Yazdi Abolghasem Yoosefi |
| author_sort | Nader Ali Nazemian Yazdi |
| collection | DOAJ |
| description |
Hemodynamic changes is of great concern during awake intubation, particularly in patients with underlying medical conditions. As heterogeneities exist in regard to the best anesthesia drugs and techniques, herein, we aimed to investigate the effects of Lidocaine 10% spray compared to trans tracheal glossopharyngeal nerve block in hemodynamic stability in patients undergoing awake intubation. A total of 62 patients were included in this randomized clinical trial. Using a longitudinal interventional design, hemodynamic measures were statistically compared before intubation, one minute after intubation, and five minutes after intubation. The first group underwent topical anesthesia with Lidocaine 10% sprayed on the base of tongue and tonsillar pillar while the second group underwent trans tracheal and glossopharyngeal nerve block with simultaneous injection of Lidocaine 2%. Our results indicated that all hemodynamic parameters except for the pulse rate in both groups were significantly reduced after the intubation, which indicates the effectiveness of the interventions. However, the reduction in SBP, DBP, and MAP was significantly lower in the nerve block group compared to the Lidocaine spray group. Regarding the pulse rate, despite the significant decrease in the group of patients undergoing nerve block, those undergoing anesthesia with Lidocaine spray experienced a significant increase in the heart rate in the first minute after the operation. Finally, our research provides substantiation that employing a glossopharyngeal nerve block and trans tracheal block constitutes an efficacious method for local anesthetic during conscious intubation and can be a promising technique.
|
| first_indexed | 2024-04-24T12:30:05Z |
| format | Article |
| id | doaj.art-d1967396633a413cb18374ac6a17ddae |
| institution | Directory Open Access Journal |
| issn | 0044-6025 1735-9694 |
| language | English |
| last_indexed | 2024-04-24T12:30:05Z |
| publishDate | 2024-03-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Acta Medica Iranica |
| spelling | doaj.art-d1967396633a413cb18374ac6a17ddae2024-04-08T06:25:17ZengTehran University of Medical SciencesActa Medica Iranica0044-60251735-96942024-03-0161910.18502/acta.v61i9.15290The Effects of Topical Anesthesia With Lidocaine 10% Spray Compared to Trans Tracheal and Glossopharyngeal Nerve Block in Hemodynamic Stability During Awake Intubation: A Randomized Controlled TrialNader Ali Nazemian Yazdi0Abolghasem Yoosefi1Department of Anesthesiology and Pain Medicine, Amir A’lam Hospital, Tehran University of Medical Sciences, Tehran, IranDepartment of Anesthesiology and Pain Medicine, Amir A’lam Hospital, Tehran University of Medical Sciences, Tehran, Iran Hemodynamic changes is of great concern during awake intubation, particularly in patients with underlying medical conditions. As heterogeneities exist in regard to the best anesthesia drugs and techniques, herein, we aimed to investigate the effects of Lidocaine 10% spray compared to trans tracheal glossopharyngeal nerve block in hemodynamic stability in patients undergoing awake intubation. A total of 62 patients were included in this randomized clinical trial. Using a longitudinal interventional design, hemodynamic measures were statistically compared before intubation, one minute after intubation, and five minutes after intubation. The first group underwent topical anesthesia with Lidocaine 10% sprayed on the base of tongue and tonsillar pillar while the second group underwent trans tracheal and glossopharyngeal nerve block with simultaneous injection of Lidocaine 2%. Our results indicated that all hemodynamic parameters except for the pulse rate in both groups were significantly reduced after the intubation, which indicates the effectiveness of the interventions. However, the reduction in SBP, DBP, and MAP was significantly lower in the nerve block group compared to the Lidocaine spray group. Regarding the pulse rate, despite the significant decrease in the group of patients undergoing nerve block, those undergoing anesthesia with Lidocaine spray experienced a significant increase in the heart rate in the first minute after the operation. Finally, our research provides substantiation that employing a glossopharyngeal nerve block and trans tracheal block constitutes an efficacious method for local anesthetic during conscious intubation and can be a promising technique. https://acta.tums.ac.ir/index.php/acta/article/view/11021Hemodynamic changesLidocaine sprayTracheal intubation |
| spellingShingle | Nader Ali Nazemian Yazdi Abolghasem Yoosefi The Effects of Topical Anesthesia With Lidocaine 10% Spray Compared to Trans Tracheal and Glossopharyngeal Nerve Block in Hemodynamic Stability During Awake Intubation: A Randomized Controlled Trial Acta Medica Iranica Hemodynamic changes Lidocaine spray Tracheal intubation |
| title | The Effects of Topical Anesthesia With Lidocaine 10% Spray Compared to Trans Tracheal and Glossopharyngeal Nerve Block in Hemodynamic Stability During Awake Intubation: A Randomized Controlled Trial |
| title_full | The Effects of Topical Anesthesia With Lidocaine 10% Spray Compared to Trans Tracheal and Glossopharyngeal Nerve Block in Hemodynamic Stability During Awake Intubation: A Randomized Controlled Trial |
| title_fullStr | The Effects of Topical Anesthesia With Lidocaine 10% Spray Compared to Trans Tracheal and Glossopharyngeal Nerve Block in Hemodynamic Stability During Awake Intubation: A Randomized Controlled Trial |
| title_full_unstemmed | The Effects of Topical Anesthesia With Lidocaine 10% Spray Compared to Trans Tracheal and Glossopharyngeal Nerve Block in Hemodynamic Stability During Awake Intubation: A Randomized Controlled Trial |
| title_short | The Effects of Topical Anesthesia With Lidocaine 10% Spray Compared to Trans Tracheal and Glossopharyngeal Nerve Block in Hemodynamic Stability During Awake Intubation: A Randomized Controlled Trial |
| title_sort | effects of topical anesthesia with lidocaine 10 spray compared to trans tracheal and glossopharyngeal nerve block in hemodynamic stability during awake intubation a randomized controlled trial |
| topic | Hemodynamic changes Lidocaine spray Tracheal intubation |
| url | https://acta.tums.ac.ir/index.php/acta/article/view/11021 |
| work_keys_str_mv | AT naderalinazemianyazdi theeffectsoftopicalanesthesiawithlidocaine10spraycomparedtotranstrachealandglossopharyngealnerveblockinhemodynamicstabilityduringawakeintubationarandomizedcontrolledtrial AT abolghasemyoosefi theeffectsoftopicalanesthesiawithlidocaine10spraycomparedtotranstrachealandglossopharyngealnerveblockinhemodynamicstabilityduringawakeintubationarandomizedcontrolledtrial AT naderalinazemianyazdi effectsoftopicalanesthesiawithlidocaine10spraycomparedtotranstrachealandglossopharyngealnerveblockinhemodynamicstabilityduringawakeintubationarandomizedcontrolledtrial AT abolghasemyoosefi effectsoftopicalanesthesiawithlidocaine10spraycomparedtotranstrachealandglossopharyngealnerveblockinhemodynamicstabilityduringawakeintubationarandomizedcontrolledtrial |