Multiple Myeloma-Derived Extracellular Vesicles Modulate the Bone Marrow Immune Microenvironment

Multiple Myeloma-Derived Extracellular Vesicles Modulate the Bone Marrow Immune Microenvironment

Multiple myeloma (MM), the third most frequent hematological cancer worldwide, is characterized by the proliferation of neoplastic plasma cells in the bone marrow (BM). One of the hallmarks of MM is a permissive BM microenvironment. Increasing evidence suggests that cell-to-cell communication betwee...

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Bibliographic Details
Main Authors: Raquel Lopes, Joana Caetano, Filipa Barahona, Carolina Pestana, Bruna Velosa Ferreira, Diana Lourenço, Ana C. Queirós, Carlos Bilreiro, Noam Shemesh, Hans Christian Beck, Ana Sofia Carvalho, Rune Matthiesen, Bjarne Bogen, Bruno Costa-Silva, Karine Serre, Emilie Arnault Carneiro, Cristina João
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
MOPC315.BM cells
multiple myeloma
mouse model
tumor immune microenvironment
extracellular vesicles
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.909880/full

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