Association of serum level of interleukin-33 and insulin resistance in overt and subclinical hypothyroidism patients
Hypothyroidism is a condition that occurs when the thyroid gland fails to produce an adequate amount of the hormone thyroid, as a result of factors for example hypothalamic or pituitary gland disease, common tissue resistance to thyroid hormones, and thyroid gland diseases. It's the most pr...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Bangladesh Society for Microbiology, Immunology, and Advanced Biotechnology
2023-12-01
|
Series: | Journal of Advanced Biotechnology and Experimental Therapeutics |
Subjects: | |
Online Access: | http://www.ejmanager.com/fulltextpdf.php?mno=155253 |
_version_ | 1827762674607325184 |
---|---|
author | Zainab Abdul Hussein Jabbar Hanaa Addai Ali Rawaa Adday Ali Mohauman Mohammed Majeed AlRufaie |
author_facet | Zainab Abdul Hussein Jabbar Hanaa Addai Ali Rawaa Adday Ali Mohauman Mohammed Majeed AlRufaie |
author_sort | Zainab Abdul Hussein Jabbar |
collection | DOAJ |
description | Hypothyroidism is a condition that occurs when the thyroid gland fails to produce an adequate amount of the hormone thyroid, as a result of factors for example hypothalamic or pituitary gland disease, common tissue resistance to thyroid hormones, and thyroid gland diseases. It's the most prevalent thyroid disorder. Interleukin-33 (IL-33) is a nuclear cytokine of the IL-1 family members that is abundantly expressed during homeostasis and inflammation in endothelial, epithelial, and fibroblast-like cells. It is worth noting that higher IL33 levels have been associated with insulin resistance.
Aims the study: Its purpose was to examine the correlation between insulin resistance and IL33 in patients with hypothyroidism by measuring their IL33 levels. In a case-control study, 180 people were recruited and split into three categories: those with overt hypothyroidism (60), those with subclinical hypothyroidism (60), and those who were otherwise healthy (60). were of a similar age range to the patient (between 20 and 55), with 55.5% female participants and 44.5% male participants. [ J Adv Biotechnol Exp Ther 2023; 6(3.000): 575-583] |
first_indexed | 2024-03-11T10:33:56Z |
format | Article |
id | doaj.art-d19891ae132445db945d1c8097259ce6 |
institution | Directory Open Access Journal |
issn | 2616-4760 |
language | English |
last_indexed | 2024-03-11T10:33:56Z |
publishDate | 2023-12-01 |
publisher | Bangladesh Society for Microbiology, Immunology, and Advanced Biotechnology |
record_format | Article |
series | Journal of Advanced Biotechnology and Experimental Therapeutics |
spelling | doaj.art-d19891ae132445db945d1c8097259ce62023-11-14T11:57:30ZengBangladesh Society for Microbiology, Immunology, and Advanced BiotechnologyJournal of Advanced Biotechnology and Experimental Therapeutics2616-47602023-12-016357558310.5455/jabet.2023.d150155253Association of serum level of interleukin-33 and insulin resistance in overt and subclinical hypothyroidism patientsZainab Abdul Hussein Jabbar0Hanaa Addai Ali1Rawaa Adday Ali2Mohauman Mohammed Majeed AlRufaieDepartment of Chemistry, Faculty of Science, University of Kufa, Najaf Department of Chemistry, Faculty of Science, University of Kufa, Najaf Microbiology Department, College of Veterinary Medicine, Al-Qasim Green UniversityHypothyroidism is a condition that occurs when the thyroid gland fails to produce an adequate amount of the hormone thyroid, as a result of factors for example hypothalamic or pituitary gland disease, common tissue resistance to thyroid hormones, and thyroid gland diseases. It's the most prevalent thyroid disorder. Interleukin-33 (IL-33) is a nuclear cytokine of the IL-1 family members that is abundantly expressed during homeostasis and inflammation in endothelial, epithelial, and fibroblast-like cells. It is worth noting that higher IL33 levels have been associated with insulin resistance. Aims the study: Its purpose was to examine the correlation between insulin resistance and IL33 in patients with hypothyroidism by measuring their IL33 levels. In a case-control study, 180 people were recruited and split into three categories: those with overt hypothyroidism (60), those with subclinical hypothyroidism (60), and those who were otherwise healthy (60). were of a similar age range to the patient (between 20 and 55), with 55.5% female participants and 44.5% male participants. [ J Adv Biotechnol Exp Ther 2023; 6(3.000): 575-583]http://www.ejmanager.com/fulltextpdf.php?mno=155253interlukine-33hypothyroidismsubclinical hypothyroidismovert hypothyroidism, |
spellingShingle | Zainab Abdul Hussein Jabbar Hanaa Addai Ali Rawaa Adday Ali Mohauman Mohammed Majeed AlRufaie Association of serum level of interleukin-33 and insulin resistance in overt and subclinical hypothyroidism patients Journal of Advanced Biotechnology and Experimental Therapeutics interlukine-33 hypothyroidism subclinical hypothyroidism overt hypothyroidism, |
title | Association of serum level of interleukin-33 and insulin resistance in overt and subclinical hypothyroidism patients |
title_full | Association of serum level of interleukin-33 and insulin resistance in overt and subclinical hypothyroidism patients |
title_fullStr | Association of serum level of interleukin-33 and insulin resistance in overt and subclinical hypothyroidism patients |
title_full_unstemmed | Association of serum level of interleukin-33 and insulin resistance in overt and subclinical hypothyroidism patients |
title_short | Association of serum level of interleukin-33 and insulin resistance in overt and subclinical hypothyroidism patients |
title_sort | association of serum level of interleukin 33 and insulin resistance in overt and subclinical hypothyroidism patients |
topic | interlukine-33 hypothyroidism subclinical hypothyroidism overt hypothyroidism, |
url | http://www.ejmanager.com/fulltextpdf.php?mno=155253 |
work_keys_str_mv | AT zainababdulhusseinjabbar associationofserumlevelofinterleukin33andinsulinresistanceinovertandsubclinicalhypothyroidismpatients AT hanaaaddaiali associationofserumlevelofinterleukin33andinsulinresistanceinovertandsubclinicalhypothyroidismpatients AT rawaaaddayali associationofserumlevelofinterleukin33andinsulinresistanceinovertandsubclinicalhypothyroidismpatients AT mohaumanmohammedmajeedalrufaie associationofserumlevelofinterleukin33andinsulinresistanceinovertandsubclinicalhypothyroidismpatients |