Clinical usefulness of end‐tidal CO2 measured using a portable capnometer in patients with respiratory disease
Abstract Introduction This study aimed to evaluate the correlation and agreement between end‐tidal CO2 (EtCO2) measured with the novel portable capnometer (CapnoEye®) and partial pressure of arterial carbon dioxide (PaCO2) levels in patients with respiratory diseases and to compare the efficacy of E...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-02-01
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| Series: | The Clinical Respiratory Journal |
| Subjects: | |
| Online Access: | https://doi.org/10.1111/crj.13577 |
| _version_ | 1797935997788356608 |
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| author | Manabu Suzuki Shota Fujimoto Keita Sakamoto Kentaro Tamura Satoru Ishii Motoyasu Iikura Shinyu Izumi Yuichiro Takeda Masayuki Hojo Haruhito Sugiyama |
| author_facet | Manabu Suzuki Shota Fujimoto Keita Sakamoto Kentaro Tamura Satoru Ishii Motoyasu Iikura Shinyu Izumi Yuichiro Takeda Masayuki Hojo Haruhito Sugiyama |
| author_sort | Manabu Suzuki |
| collection | DOAJ |
| description | Abstract Introduction This study aimed to evaluate the correlation and agreement between end‐tidal CO2 (EtCO2) measured with the novel portable capnometer (CapnoEye®) and partial pressure of arterial carbon dioxide (PaCO2) levels in patients with respiratory diseases and to compare the efficacy of EtCO2 and PvCO2 in predicting PaCO2 levels. Methods We analyzed the correlation and the agreement between EtCO2 and PaCO2 and between PvCO2 and PaCO2 using Pearson's moment correlation coefficient in patients with type 1 and type 2 respiratory failure and both groups overall. Results A total of 100 samples were included that comprised 67 men (67%). The mean age of the subjects was 77 ± 13 years. Chronic obstructive pulmonary disease (COPD) (43%) was the most common disease. There was a high correlation between EtCO2 and PaCO2 (r = 0.88; p < 0.0001). Sixty‐six PvCO2 samples were obtained, and there was a high correlation between PvCO2 and PaCO2 (r = 0.81; p < 0.0001). Regarding type 2 respiratory failure, there was a high correlation between EtCO2 and PaCO2 (r = 0.81). The Bland–Altman analysis between PaCO2 and EtCO2 revealed a bias of 5.7 mmHg, with limits of agreement ranging from −5.1 mmHg to 16.5 mmHg. In contrast, the analysis between PaCO2 and PvCO2 revealed a bias of −6.8 mmHg, and the limits of agreement ranged from −22.13 mmHg to 8.53 mmHg. Conclusion EtCO2 measured by CapnoEye® was significantly correlated to PaCO2 levels in patients with respiratory diseases. Moreover, CapnoEye® may be more useful for predicting hypercapnia conditions in which respiratory diseases are compared with measure PvCO2. |
| first_indexed | 2024-04-10T18:23:53Z |
| format | Article |
| id | doaj.art-d19e082969e842e69234c353c423546c |
| institution | Directory Open Access Journal |
| issn | 1752-6981 1752-699X |
| language | English |
| last_indexed | 2024-04-10T18:23:53Z |
| publishDate | 2023-02-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Clinical Respiratory Journal |
| spelling | doaj.art-d19e082969e842e69234c353c423546c2023-02-02T06:54:35ZengWileyThe Clinical Respiratory Journal1752-69811752-699X2023-02-011729610410.1111/crj.13577Clinical usefulness of end‐tidal CO2 measured using a portable capnometer in patients with respiratory diseaseManabu Suzuki0Shota Fujimoto1Keita Sakamoto2Kentaro Tamura3Satoru Ishii4Motoyasu Iikura5Shinyu Izumi6Yuichiro Takeda7Masayuki Hojo8Haruhito Sugiyama9Department of Respiratory Medicine National Center for Global Health and Medicine Tokyo JapanDepartment of Respiratory Medicine National Center for Global Health and Medicine Tokyo JapanDepartment of Respiratory Medicine National Center for Global Health and Medicine Tokyo JapanDepartment of Respiratory Medicine National Center for Global Health and Medicine Tokyo JapanDepartment of Respiratory Medicine National Center for Global Health and Medicine Tokyo JapanDepartment of Respiratory Medicine National Center for Global Health and Medicine Tokyo JapanDepartment of Respiratory Medicine National Center for Global Health and Medicine Tokyo JapanDepartment of Respiratory Medicine National Center for Global Health and Medicine Tokyo JapanDepartment of Respiratory Medicine National Center for Global Health and Medicine Tokyo JapanDepartment of Respiratory Medicine National Center for Global Health and Medicine Tokyo JapanAbstract Introduction This study aimed to evaluate the correlation and agreement between end‐tidal CO2 (EtCO2) measured with the novel portable capnometer (CapnoEye®) and partial pressure of arterial carbon dioxide (PaCO2) levels in patients with respiratory diseases and to compare the efficacy of EtCO2 and PvCO2 in predicting PaCO2 levels. Methods We analyzed the correlation and the agreement between EtCO2 and PaCO2 and between PvCO2 and PaCO2 using Pearson's moment correlation coefficient in patients with type 1 and type 2 respiratory failure and both groups overall. Results A total of 100 samples were included that comprised 67 men (67%). The mean age of the subjects was 77 ± 13 years. Chronic obstructive pulmonary disease (COPD) (43%) was the most common disease. There was a high correlation between EtCO2 and PaCO2 (r = 0.88; p < 0.0001). Sixty‐six PvCO2 samples were obtained, and there was a high correlation between PvCO2 and PaCO2 (r = 0.81; p < 0.0001). Regarding type 2 respiratory failure, there was a high correlation between EtCO2 and PaCO2 (r = 0.81). The Bland–Altman analysis between PaCO2 and EtCO2 revealed a bias of 5.7 mmHg, with limits of agreement ranging from −5.1 mmHg to 16.5 mmHg. In contrast, the analysis between PaCO2 and PvCO2 revealed a bias of −6.8 mmHg, and the limits of agreement ranged from −22.13 mmHg to 8.53 mmHg. Conclusion EtCO2 measured by CapnoEye® was significantly correlated to PaCO2 levels in patients with respiratory diseases. Moreover, CapnoEye® may be more useful for predicting hypercapnia conditions in which respiratory diseases are compared with measure PvCO2.https://doi.org/10.1111/crj.13577capnometerEtCO2PaCO2PvCO2respiratory carerespiratory medicine |
| spellingShingle | Manabu Suzuki Shota Fujimoto Keita Sakamoto Kentaro Tamura Satoru Ishii Motoyasu Iikura Shinyu Izumi Yuichiro Takeda Masayuki Hojo Haruhito Sugiyama Clinical usefulness of end‐tidal CO2 measured using a portable capnometer in patients with respiratory disease The Clinical Respiratory Journal capnometer EtCO2 PaCO2 PvCO2 respiratory care respiratory medicine |
| title | Clinical usefulness of end‐tidal CO2 measured using a portable capnometer in patients with respiratory disease |
| title_full | Clinical usefulness of end‐tidal CO2 measured using a portable capnometer in patients with respiratory disease |
| title_fullStr | Clinical usefulness of end‐tidal CO2 measured using a portable capnometer in patients with respiratory disease |
| title_full_unstemmed | Clinical usefulness of end‐tidal CO2 measured using a portable capnometer in patients with respiratory disease |
| title_short | Clinical usefulness of end‐tidal CO2 measured using a portable capnometer in patients with respiratory disease |
| title_sort | clinical usefulness of end tidal co2 measured using a portable capnometer in patients with respiratory disease |
| topic | capnometer EtCO2 PaCO2 PvCO2 respiratory care respiratory medicine |
| url | https://doi.org/10.1111/crj.13577 |
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