SARS-CoV-2 variants – Evolution, spike protein, and vaccines
Abstracts: Despite the rising natural and vaccines mediated immunity, several countries have experienced a resurgence of the Coronavirus disease of 2019 (COVID-19) due to the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants. From Alpha to Omicron, the variants of co...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-08-01
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| Series: | Biomedical Journal |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2319417022000725 |
| _version_ | 1828404758912696320 |
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| author | Kai-Wei K. Chen Daniel Tsung-Ning Huang Li-Min Huang |
| author_facet | Kai-Wei K. Chen Daniel Tsung-Ning Huang Li-Min Huang |
| author_sort | Kai-Wei K. Chen |
| collection | DOAJ |
| description | Abstracts: Despite the rising natural and vaccines mediated immunity, several countries have experienced a resurgence of the Coronavirus disease of 2019 (COVID-19) due to the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants. From Alpha to Omicron, the variants of concern (VOC) have evolved several spike protein mutations that may have an impact on virus characteristics, such as transmissibility and antigenicity. In this review, we describe the evolution of SARS-CoV-2, summarize current knowledge of epidemiological and clinical features of the variants, and discuss the response strategies in terms of vaccines to reduce the burden of COVID-19. |
| first_indexed | 2024-12-10T10:41:21Z |
| format | Article |
| id | doaj.art-d1a5b0b1d42545df8057517a2013be4e |
| institution | Directory Open Access Journal |
| issn | 2319-4170 |
| language | English |
| last_indexed | 2024-12-10T10:41:21Z |
| publishDate | 2022-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Biomedical Journal |
| spelling | doaj.art-d1a5b0b1d42545df8057517a2013be4e2022-12-22T01:52:19ZengElsevierBiomedical Journal2319-41702022-08-01454573579SARS-CoV-2 variants – Evolution, spike protein, and vaccinesKai-Wei K. Chen0Daniel Tsung-Ning Huang1Li-Min Huang2Department of Pediatrics, MacKay Children's Hospital, Taipei, TaiwanDepartment of Pediatrics, MacKay Children's Hospital, Taipei, Taiwan; Department of Medicine, MacKay Medical College, Taipei, TaiwanDepartment of Pediatrics, National Taiwan University Children's Hospital, National Taiwan University College of Medicine, Taipei, Taiwan; Corresponding author. Department of Pediatrics, National Taiwan University Children's Hospital, National Taiwan University College of Medicine, 8, Zhongshan S. Rd., Zhongzheng Dist., Taipei, Taiwan.Abstracts: Despite the rising natural and vaccines mediated immunity, several countries have experienced a resurgence of the Coronavirus disease of 2019 (COVID-19) due to the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants. From Alpha to Omicron, the variants of concern (VOC) have evolved several spike protein mutations that may have an impact on virus characteristics, such as transmissibility and antigenicity. In this review, we describe the evolution of SARS-CoV-2, summarize current knowledge of epidemiological and clinical features of the variants, and discuss the response strategies in terms of vaccines to reduce the burden of COVID-19.http://www.sciencedirect.com/science/article/pii/S2319417022000725COVID-19SARS-CoV-2Spike mutationsVariant of concernVaccines |
| spellingShingle | Kai-Wei K. Chen Daniel Tsung-Ning Huang Li-Min Huang SARS-CoV-2 variants – Evolution, spike protein, and vaccines Biomedical Journal COVID-19 SARS-CoV-2 Spike mutations Variant of concern Vaccines |
| title | SARS-CoV-2 variants – Evolution, spike protein, and vaccines |
| title_full | SARS-CoV-2 variants – Evolution, spike protein, and vaccines |
| title_fullStr | SARS-CoV-2 variants – Evolution, spike protein, and vaccines |
| title_full_unstemmed | SARS-CoV-2 variants – Evolution, spike protein, and vaccines |
| title_short | SARS-CoV-2 variants – Evolution, spike protein, and vaccines |
| title_sort | sars cov 2 variants evolution spike protein and vaccines |
| topic | COVID-19 SARS-CoV-2 Spike mutations Variant of concern Vaccines |
| url | http://www.sciencedirect.com/science/article/pii/S2319417022000725 |
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