Therapeutic Implications of Epidermal Growth Factor Receptor (EGFR) in the Treatment of Metastatic Gastric/GEJ Cancer

Therapeutic Implications of Epidermal Growth Factor Receptor (EGFR) in the Treatment of Metastatic Gastric/GEJ Cancer

Gastric cancer remains third leading cause of global cancer mortality and is the fifth most common type of cancer in the United States. A select number of gastric cancers harbor alterations in EGFR and/or have amplification/overexpression in the HER2; 2–35 and 9–38%, respectively. The advent of next...

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Bibliographic Details
Main Authors: Jacob J. Adashek, Yadis Arroyo-Martinez, Arjun K. Menta, Razelle Kurzrock, Shumei Kato
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Oncology
Subjects:
EGFR
next-generation sequencing
targeted therapy
gastric carcinoma
ctDNA
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.01312/full

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