Cocaine Directly Impairs Memory Extinction and Alters Brain DNA Methylation Dynamics in Honey Bees

Cocaine Directly Impairs Memory Extinction and Alters Brain DNA Methylation Dynamics in Honey Bees

Drug addiction is a chronic relapsing behavioral disorder. The high relapse rate has often been attributed to the perseverance of drug-associated memories due to high incentive salience of stimuli learnt under the influence of drugs. Drug addiction has also been interpreted as a memory disorder sinc...

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Bibliographic Details
Main Authors: Eirik Søvik, Pauline Berthier, William P. Klare, Paul Helliwell, Edwina L. S. Buckle, Jenny A. Plath, Andrew B. Barron, Ryszard Maleszka
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Physiology
Subjects:
addiction
Apis mellifera
DNMT3
demethylation
epigenomics
TET
Online Access:http://journal.frontiersin.org/article/10.3389/fphys.2018.00079/full

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