Osthole Suppresses Knee Osteoarthritis Development by Enhancing Autophagy Activated via the AMPK/ULK1 Pathway

Osthole Suppresses Knee Osteoarthritis Development by Enhancing Autophagy Activated via the AMPK/ULK1 Pathway

Knee osteoarthritis (KOA) is an increasingly prevalent heterogeneous disease characterized by cartilage erosion and inflammation. As the main chemical constituent of Angelicae Pubescentis Radix (APR), an anti-inflammatory herbal medicine, the potential biological effects and underlying mechanism of...

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Bibliographic Details
Main Authors: Teng Ma, Xiangpeng Wang, Wenjing Qu, Lingsen Yang, Cheng Jing, Bingrui Zhu, Yongkui Zhang, Wenpeng Xie
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Molecules
Subjects:
osthole
AMPK/ULK1
autophagy
degeneration
knee osteoarthritis
Online Access:https://www.mdpi.com/1420-3049/27/23/8624

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