JMJD6 Regulates Splicing of Its Own Gene Resulting in Alternatively Spliced Isoforms with Different Nuclear Targets

JMJD6 Regulates Splicing of Its Own Gene Resulting in Alternatively Spliced Isoforms with Different Nuclear Targets

Jumonji-domain-containing protein 6 (JMJD6) is a Fe(II) and 2-oxogluterate (2OG) dependent oxygenase involved in gene regulation through post-translationally modifying nuclear proteins. It is highly expressed in many cancer types and linked to tumor progression and metastasis. Four alternatively-spl...

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Bibliographic Details
Main Authors: Nikoleta Raguz, Astrid Heim, Eden Engal, Juste Wesche, Juliane Merl-Pham, Stefanie M. Hauck, Steffen Erkelenz, Heiner Schaal, Olivier Bensaude, Alexander Wolf, Maayan Salton, Angelika Böttger
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
splicing
polyS domain
hydroxylation
Online Access:https://www.mdpi.com/1422-0067/21/18/6618

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