The Effects of Aflatoxin B1 Intake in Assaf Dairy Ewes on Aflatoxin M1 Excretion, Milk Yield, Haematology and Biochemical Profile
The aim of this study was to investigate the in vivo transfer of aflatoxin B1 (AFB1) to Assaf ewes’ milk (aflatoxin M1, AFM1) and its effect on animal performance and health. Thirty Assaf ewes were allocated to three groups (C, L, H), and received a different individual daily dose of AFB1 (0, 40 and...
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| Format: | Article |
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MDPI AG
2023-01-01
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| Series: | Animals |
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| Online Access: | https://www.mdpi.com/2076-2615/13/3/436 |
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| author | Raúl Bodas F. Javier Giráldez Sara Olmedo Marta Herrera Susana Lorán Agustín Ariño Secundino López Alberto Benito Teresa Juan |
| author_facet | Raúl Bodas F. Javier Giráldez Sara Olmedo Marta Herrera Susana Lorán Agustín Ariño Secundino López Alberto Benito Teresa Juan |
| author_sort | Raúl Bodas |
| collection | DOAJ |
| description | The aim of this study was to investigate the in vivo transfer of aflatoxin B1 (AFB1) to Assaf ewes’ milk (aflatoxin M1, AFM1) and its effect on animal performance and health. Thirty Assaf ewes were allocated to three groups (C, L, H), and received a different individual daily dose of AFB1 (0, 40 and 80 μg) for 13 days. Milk (days 1, 2, 3, 4, 7, 14, 16 and 18) and blood (days 1, 7, 14 and 18) samples were collected. Milk yield, composition (except protein) and somatic cell counts (SCC) were not affected by AFB1 intake (<i>p</i> > 0.05). Haemoglobin concentration increased (<i>p</i> < 0.05) and haematocrit and alanine aminotransferase levels tended to increase (<i>p</i> < 0.10) in group H on day 14. AFM1 excretion was highly variable and detected in L and H animals from days 1 to 16 (3 days increase, 10 days steady-state, 3 days clearance). Carry-over rate (0.23%) was significantly higher in L (0.22–0.34%) than in H (0.16–0.19%) animals (<i>p</i> < 0.05). AFB1 daily doses of 40 to 80 µg do not impair milk yield; however, it may start affecting animals’ health. Milk AFM1 depends mainly on the AFB1 intake whereas carryover rate is positively influenced by the level of milk production. |
| first_indexed | 2024-03-11T09:54:25Z |
| format | Article |
| id | doaj.art-d1b6a1bd1f2247bc86c840ade457892c |
| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-03-11T09:54:25Z |
| publishDate | 2023-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Animals |
| spelling | doaj.art-d1b6a1bd1f2247bc86c840ade457892c2023-11-16T16:00:50ZengMDPI AGAnimals2076-26152023-01-0113343610.3390/ani13030436The Effects of Aflatoxin B1 Intake in Assaf Dairy Ewes on Aflatoxin M1 Excretion, Milk Yield, Haematology and Biochemical ProfileRaúl Bodas0F. Javier Giráldez1Sara Olmedo2Marta Herrera3Susana Lorán4Agustín Ariño5Secundino López6Alberto Benito7Teresa Juan8Agrarian Technological Institute of Castile and Leon (ITACyL), Ctra. Burgos, Km 119, 47071 Valladolid, SpainInstituto de Ganadería de Montaña (CSIC-Universidad De León), Finca Marzanas s/n, 24346 Grulleros, SpainAgrarian Technological Institute of Castile and Leon (ITACyL), Ctra. Burgos, Km 119, 47071 Valladolid, SpainFacultad de Veterinaria, Instituto Agroalimentario de Aragón-IA2 (Universidad de Zaragoza-CITA), 50013 Zaragoza, SpainFacultad de Veterinaria, Instituto Agroalimentario de Aragón-IA2 (Universidad de Zaragoza-CITA), 50013 Zaragoza, SpainFacultad de Veterinaria, Instituto Agroalimentario de Aragón-IA2 (Universidad de Zaragoza-CITA), 50013 Zaragoza, SpainInstituto de Ganadería de Montaña (CSIC-Universidad De León), Finca Marzanas s/n, 24346 Grulleros, SpainAgrarian Technological Institute of Castile and Leon (ITACyL), Ctra. Burgos, Km 119, 47071 Valladolid, SpainFacultad de Veterinaria, Instituto Agroalimentario de Aragón-IA2 (Universidad de Zaragoza-CITA), 50013 Zaragoza, SpainThe aim of this study was to investigate the in vivo transfer of aflatoxin B1 (AFB1) to Assaf ewes’ milk (aflatoxin M1, AFM1) and its effect on animal performance and health. Thirty Assaf ewes were allocated to three groups (C, L, H), and received a different individual daily dose of AFB1 (0, 40 and 80 μg) for 13 days. Milk (days 1, 2, 3, 4, 7, 14, 16 and 18) and blood (days 1, 7, 14 and 18) samples were collected. Milk yield, composition (except protein) and somatic cell counts (SCC) were not affected by AFB1 intake (<i>p</i> > 0.05). Haemoglobin concentration increased (<i>p</i> < 0.05) and haematocrit and alanine aminotransferase levels tended to increase (<i>p</i> < 0.10) in group H on day 14. AFM1 excretion was highly variable and detected in L and H animals from days 1 to 16 (3 days increase, 10 days steady-state, 3 days clearance). Carry-over rate (0.23%) was significantly higher in L (0.22–0.34%) than in H (0.16–0.19%) animals (<i>p</i> < 0.05). AFB1 daily doses of 40 to 80 µg do not impair milk yield; however, it may start affecting animals’ health. Milk AFM1 depends mainly on the AFB1 intake whereas carryover rate is positively influenced by the level of milk production.https://www.mdpi.com/2076-2615/13/3/436aflatoxin B1aflatoxin M1milkdairy ewesAssafcarryover |
| spellingShingle | Raúl Bodas F. Javier Giráldez Sara Olmedo Marta Herrera Susana Lorán Agustín Ariño Secundino López Alberto Benito Teresa Juan The Effects of Aflatoxin B1 Intake in Assaf Dairy Ewes on Aflatoxin M1 Excretion, Milk Yield, Haematology and Biochemical Profile Animals aflatoxin B1 aflatoxin M1 milk dairy ewes Assaf carryover |
| title | The Effects of Aflatoxin B1 Intake in Assaf Dairy Ewes on Aflatoxin M1 Excretion, Milk Yield, Haematology and Biochemical Profile |
| title_full | The Effects of Aflatoxin B1 Intake in Assaf Dairy Ewes on Aflatoxin M1 Excretion, Milk Yield, Haematology and Biochemical Profile |
| title_fullStr | The Effects of Aflatoxin B1 Intake in Assaf Dairy Ewes on Aflatoxin M1 Excretion, Milk Yield, Haematology and Biochemical Profile |
| title_full_unstemmed | The Effects of Aflatoxin B1 Intake in Assaf Dairy Ewes on Aflatoxin M1 Excretion, Milk Yield, Haematology and Biochemical Profile |
| title_short | The Effects of Aflatoxin B1 Intake in Assaf Dairy Ewes on Aflatoxin M1 Excretion, Milk Yield, Haematology and Biochemical Profile |
| title_sort | effects of aflatoxin b1 intake in assaf dairy ewes on aflatoxin m1 excretion milk yield haematology and biochemical profile |
| topic | aflatoxin B1 aflatoxin M1 milk dairy ewes Assaf carryover |
| url | https://www.mdpi.com/2076-2615/13/3/436 |
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