High-frequency and brief-pulse stimulation pulses terminate cortical electrical stimulation-induced afterdischarges
Brief-pulse stimulation at 50 Hz has been shown to terminate afterdischarges observed in epilepsy patients. However, the optimal pulse stimulation parameters for terminating cortical electrical stimulation-induced afterdischarges remain unclear. In the present study, we examined the effects of diffe...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2017-01-01
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| Series: | Neural Regeneration Research |
| Subjects: | |
| Online Access: | http://www.nrronline.org/article.asp?issn=1673-5374;year=2017;volume=12;issue=6;spage=938;epage=944;aulast=Ren |
| _version_ | 1818488715254693888 |
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| author | Zhi-wei Ren Yong-jie Li Tao Yu Duan-yu Ni Guo-jun Zhang Wei Du Yuan-yuan Piao Xiao-xia Zhou |
| author_facet | Zhi-wei Ren Yong-jie Li Tao Yu Duan-yu Ni Guo-jun Zhang Wei Du Yuan-yuan Piao Xiao-xia Zhou |
| author_sort | Zhi-wei Ren |
| collection | DOAJ |
| description | Brief-pulse stimulation at 50 Hz has been shown to terminate afterdischarges observed in epilepsy patients. However, the optimal pulse stimulation parameters for terminating cortical electrical stimulation-induced afterdischarges remain unclear. In the present study, we examined the effects of different brief-pulse stimulation frequencies (5, 50 and 100 Hz) on cortical electrical stimulation-induced afterdischarges in 10 patients with refractory epilepsy. Results demonstrated that brief-pulse stimulation could terminate cortical electrical stimulation-induced afterdischarges in refractory epilepsy patients. In conclusion, (1) a brief-pulse stimulation was more effective when the afterdischarge did not extend to the surrounding brain area. (2) A higher brief-pulse stimulation frequency (especially 100 Hz) was more likely to terminate an afterdischarge. (3) A low current intensity of brief-pulse stimulation was more likely to terminate an afterdischarge |
| first_indexed | 2024-12-10T16:54:45Z |
| format | Article |
| id | doaj.art-d1b9cc04981e40868ad692a028ec5a0f |
| institution | Directory Open Access Journal |
| issn | 1673-5374 |
| language | English |
| last_indexed | 2024-12-10T16:54:45Z |
| publishDate | 2017-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Neural Regeneration Research |
| spelling | doaj.art-d1b9cc04981e40868ad692a028ec5a0f2022-12-22T01:40:47ZengWolters Kluwer Medknow PublicationsNeural Regeneration Research1673-53742017-01-0112693894410.4103/1673-5374.208576High-frequency and brief-pulse stimulation pulses terminate cortical electrical stimulation-induced afterdischargesZhi-wei RenYong-jie LiTao YuDuan-yu NiGuo-jun ZhangWei DuYuan-yuan PiaoXiao-xia ZhouBrief-pulse stimulation at 50 Hz has been shown to terminate afterdischarges observed in epilepsy patients. However, the optimal pulse stimulation parameters for terminating cortical electrical stimulation-induced afterdischarges remain unclear. In the present study, we examined the effects of different brief-pulse stimulation frequencies (5, 50 and 100 Hz) on cortical electrical stimulation-induced afterdischarges in 10 patients with refractory epilepsy. Results demonstrated that brief-pulse stimulation could terminate cortical electrical stimulation-induced afterdischarges in refractory epilepsy patients. In conclusion, (1) a brief-pulse stimulation was more effective when the afterdischarge did not extend to the surrounding brain area. (2) A higher brief-pulse stimulation frequency (especially 100 Hz) was more likely to terminate an afterdischarge. (3) A low current intensity of brief-pulse stimulation was more likely to terminate an afterdischargehttp://www.nrronline.org/article.asp?issn=1673-5374;year=2017;volume=12;issue=6;spage=938;epage=944;aulast=Rennerve regeneration; cortical electrical stimulation; afterdischarges; intractable epilepsy; functional brain mapping; high frequency stimulation; low frequency stimulation; neuromodulation; neural regeneration |
| spellingShingle | Zhi-wei Ren Yong-jie Li Tao Yu Duan-yu Ni Guo-jun Zhang Wei Du Yuan-yuan Piao Xiao-xia Zhou High-frequency and brief-pulse stimulation pulses terminate cortical electrical stimulation-induced afterdischarges Neural Regeneration Research nerve regeneration; cortical electrical stimulation; afterdischarges; intractable epilepsy; functional brain mapping; high frequency stimulation; low frequency stimulation; neuromodulation; neural regeneration |
| title | High-frequency and brief-pulse stimulation pulses terminate cortical electrical stimulation-induced afterdischarges |
| title_full | High-frequency and brief-pulse stimulation pulses terminate cortical electrical stimulation-induced afterdischarges |
| title_fullStr | High-frequency and brief-pulse stimulation pulses terminate cortical electrical stimulation-induced afterdischarges |
| title_full_unstemmed | High-frequency and brief-pulse stimulation pulses terminate cortical electrical stimulation-induced afterdischarges |
| title_short | High-frequency and brief-pulse stimulation pulses terminate cortical electrical stimulation-induced afterdischarges |
| title_sort | high frequency and brief pulse stimulation pulses terminate cortical electrical stimulation induced afterdischarges |
| topic | nerve regeneration; cortical electrical stimulation; afterdischarges; intractable epilepsy; functional brain mapping; high frequency stimulation; low frequency stimulation; neuromodulation; neural regeneration |
| url | http://www.nrronline.org/article.asp?issn=1673-5374;year=2017;volume=12;issue=6;spage=938;epage=944;aulast=Ren |
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