Seroprevalence of Hepatitis B and C virus infections among pregnant women attending antenatal care in a secondary health facility in Northern Nigeria

Objective: Viral hepatitis is a major global public health challenge with Hepatitis B virus (HBV) and Hepatitis C virus (HCV), particularly leading to chronic diseases in several millions of people together they are the most common cause of liver cirrhosis, liver cancer and deaths related to viral...

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Main Authors: Chikwendu Amaike, Libby Harry, Tolulope Afolaranmi, Alexandra Odiari, Ayobami Adesuyi, Amaka Ocheke
Format: Article
Language:English
Published: Babcock Medical Society 2023-06-01
Series:Babcock University Medical Journal
Subjects:
Online Access:https://bumj.babcock.edu.ng/index.php/bumj/article/view/171
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author Chikwendu Amaike
Libby Harry
Tolulope Afolaranmi
Alexandra Odiari
Ayobami Adesuyi
Amaka Ocheke
author_facet Chikwendu Amaike
Libby Harry
Tolulope Afolaranmi
Alexandra Odiari
Ayobami Adesuyi
Amaka Ocheke
author_sort Chikwendu Amaike
collection DOAJ
description Objective: Viral hepatitis is a major global public health challenge with Hepatitis B virus (HBV) and Hepatitis C virus (HCV), particularly leading to chronic diseases in several millions of people together they are the most common cause of liver cirrhosis, liver cancer and deaths related to viral hepatitis. They can be spread by mother-to-child transmission at birth. Despite the significant health burden it places on pregnant women and their infants, the infection has been given little attention in Nigeria and some low- and middle-income countries, and routine screening during antennal care are not done for most pregnant women. This study assessed the seroprevalence of Hepatitis B and C viral infections among pregnant women. Methods: The study was cross-sectional involving a three-year retrospective review of laboratory results of the pregnant women who accessed antenatal care in the health facility. Data extraction was done manually from facility registers and analyses were done using IBM SPSS.   Results: Laboratory results of HBV and HCV for 706 pregnant women were reviewed. The seroprevalence of HBV and HCV was 11.6% and 6.5% respectively while the seroprevalence of viral hepatitis was 18.1%. Conclusion: The high seroprevalence of viral hepatitis in this study further supports the importance of adopting global best practices to prevent the spread of the infection via mother-to-child transmission. We, therefore, re-emphasize the importance of screening for HBV and HCV as routine investigations in pregnant women.
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spelling doaj.art-d1be7e51db9942fdaf8027e072f5f9222023-07-01T04:10:48ZengBabcock Medical SocietyBabcock University Medical Journal2465-66662756-46572023-06-016110.38029/babcockuniv.med.j..v6i1.171Seroprevalence of Hepatitis B and C virus infections among pregnant women attending antenatal care in a secondary health facility in Northern NigeriaChikwendu Amaike0Libby HarryTolulope AfolaranmiAlexandra OdiariAyobami AdesuyiAmaka OchekeBabcock University Objective: Viral hepatitis is a major global public health challenge with Hepatitis B virus (HBV) and Hepatitis C virus (HCV), particularly leading to chronic diseases in several millions of people together they are the most common cause of liver cirrhosis, liver cancer and deaths related to viral hepatitis. They can be spread by mother-to-child transmission at birth. Despite the significant health burden it places on pregnant women and their infants, the infection has been given little attention in Nigeria and some low- and middle-income countries, and routine screening during antennal care are not done for most pregnant women. This study assessed the seroprevalence of Hepatitis B and C viral infections among pregnant women. Methods: The study was cross-sectional involving a three-year retrospective review of laboratory results of the pregnant women who accessed antenatal care in the health facility. Data extraction was done manually from facility registers and analyses were done using IBM SPSS.   Results: Laboratory results of HBV and HCV for 706 pregnant women were reviewed. The seroprevalence of HBV and HCV was 11.6% and 6.5% respectively while the seroprevalence of viral hepatitis was 18.1%. Conclusion: The high seroprevalence of viral hepatitis in this study further supports the importance of adopting global best practices to prevent the spread of the infection via mother-to-child transmission. We, therefore, re-emphasize the importance of screening for HBV and HCV as routine investigations in pregnant women. https://bumj.babcock.edu.ng/index.php/bumj/article/view/171Hepatitis B virusHepatitis C VirusMother-to-child-transmissionNigeriaSeroprevalence
spellingShingle Chikwendu Amaike
Libby Harry
Tolulope Afolaranmi
Alexandra Odiari
Ayobami Adesuyi
Amaka Ocheke
Seroprevalence of Hepatitis B and C virus infections among pregnant women attending antenatal care in a secondary health facility in Northern Nigeria
Babcock University Medical Journal
Hepatitis B virus
Hepatitis C Virus
Mother-to-child-transmission
Nigeria
Seroprevalence
title Seroprevalence of Hepatitis B and C virus infections among pregnant women attending antenatal care in a secondary health facility in Northern Nigeria
title_full Seroprevalence of Hepatitis B and C virus infections among pregnant women attending antenatal care in a secondary health facility in Northern Nigeria
title_fullStr Seroprevalence of Hepatitis B and C virus infections among pregnant women attending antenatal care in a secondary health facility in Northern Nigeria
title_full_unstemmed Seroprevalence of Hepatitis B and C virus infections among pregnant women attending antenatal care in a secondary health facility in Northern Nigeria
title_short Seroprevalence of Hepatitis B and C virus infections among pregnant women attending antenatal care in a secondary health facility in Northern Nigeria
title_sort seroprevalence of hepatitis b and c virus infections among pregnant women attending antenatal care in a secondary health facility in northern nigeria
topic Hepatitis B virus
Hepatitis C Virus
Mother-to-child-transmission
Nigeria
Seroprevalence
url https://bumj.babcock.edu.ng/index.php/bumj/article/view/171
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