Screening for a false unipolarity in patients treated for a major depressive disorder

Introduction The early diagnosis of bipolar II disorder remains difficult in clinical practice, hence the importance of psychometric tests. Objectives To detect hypomania in patients followed for a major depressive disorder (MDD) and to determine factors which are correlated with it. Methods...

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Main Authors: N. Regaieg, I. Baati, F. Ben Amor, M. Kallel, S. Hentati, J. Masmoudi
Format: Article
Language:English
Published: Cambridge University Press 2021-04-01
Series:European Psychiatry
Subjects:
Online Access:https://www.cambridge.org/core/product/identifier/S0924933821005332/type/journal_article
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author N. Regaieg
I. Baati
F. Ben Amor
M. Kallel
S. Hentati
J. Masmoudi
author_facet N. Regaieg
I. Baati
F. Ben Amor
M. Kallel
S. Hentati
J. Masmoudi
author_sort N. Regaieg
collection DOAJ
description Introduction The early diagnosis of bipolar II disorder remains difficult in clinical practice, hence the importance of psychometric tests. Objectives To detect hypomania in patients followed for a major depressive disorder (MDD) and to determine factors which are correlated with it. Methods This was a cross-sectional, descriptive and analytical study. It involved 40 psychiatric outpatients, who were followed for MDD (isolated or recurrent episode) at the Hedi Chaker University Hospital in Sfax (Tunisia), from January 26 to February 10, 2020. The study was conducted using a questionnaire and the Angst Hypomania Checklist-20 (HCL-20). Results The sex ratio (M/F) was 0.66 with an average age of 54.8 years. MDD started at an average age of 41.45 years. According to HCL-20, half of our sample had hypomania. The presence of hypomania was correlated with young age (p = 0.022), academic failure (p = 0.038) and smoking (p = 0.003). In addition, there was a statistically significant relationship between the presence of hypomania and the characteristics of the disease: number of depressive episodes ≥ 2 (p = 0.013), psychotic features (p = 0.038), melancholic features (p=0,025) and premature discontinuation of treatment (p = 0.003). Conclusions Our study confirmed that bipolar depression is still underdiagnosed and poorly treated. Questioning a patient about a history of hypomania would be a delicate task and would require the help of a scale, in particular the HCL -20.
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spelling doaj.art-d1bef807080747c194870cf38f37e9632023-11-17T05:06:28ZengCambridge University PressEuropean Psychiatry0924-93381778-35852021-04-0164S200S20110.1192/j.eurpsy.2021.533Screening for a false unipolarity in patients treated for a major depressive disorderN. Regaieg0I. Baati1F. Ben Amor2M. Kallel3S. Hentati4J. Masmoudi5Psychiatry “a” Department, Hedi Chaker UHC, Sfax, TunisiaPsychiatry “a” Department, Hedi Chaker University Hospital, Sfax, TunisiaPsychiatry “a” Department, Hedi Chaker University Hospital, Sfax, TunisiaPsychiatry “a” Department, Hedi Chaker UHC, Sfax, TunisiaPsychiatry “a” Department, Hedi Chaker University Hospital, Sfax, TunisiaPsychiatrie “a” Department, Hedi Chaker Hospital University -Sfax - Tunisia, sfax, Tunisia Introduction The early diagnosis of bipolar II disorder remains difficult in clinical practice, hence the importance of psychometric tests. Objectives To detect hypomania in patients followed for a major depressive disorder (MDD) and to determine factors which are correlated with it. Methods This was a cross-sectional, descriptive and analytical study. It involved 40 psychiatric outpatients, who were followed for MDD (isolated or recurrent episode) at the Hedi Chaker University Hospital in Sfax (Tunisia), from January 26 to February 10, 2020. The study was conducted using a questionnaire and the Angst Hypomania Checklist-20 (HCL-20). Results The sex ratio (M/F) was 0.66 with an average age of 54.8 years. MDD started at an average age of 41.45 years. According to HCL-20, half of our sample had hypomania. The presence of hypomania was correlated with young age (p = 0.022), academic failure (p = 0.038) and smoking (p = 0.003). In addition, there was a statistically significant relationship between the presence of hypomania and the characteristics of the disease: number of depressive episodes ≥ 2 (p = 0.013), psychotic features (p = 0.038), melancholic features (p=0,025) and premature discontinuation of treatment (p = 0.003). Conclusions Our study confirmed that bipolar depression is still underdiagnosed and poorly treated. Questioning a patient about a history of hypomania would be a delicate task and would require the help of a scale, in particular the HCL -20. https://www.cambridge.org/core/product/identifier/S0924933821005332/type/journal_articleHCL-20bipolar depressionbipolar II disorderhypomania
spellingShingle N. Regaieg
I. Baati
F. Ben Amor
M. Kallel
S. Hentati
J. Masmoudi
Screening for a false unipolarity in patients treated for a major depressive disorder
European Psychiatry
HCL-20
bipolar depression
bipolar II disorder
hypomania
title Screening for a false unipolarity in patients treated for a major depressive disorder
title_full Screening for a false unipolarity in patients treated for a major depressive disorder
title_fullStr Screening for a false unipolarity in patients treated for a major depressive disorder
title_full_unstemmed Screening for a false unipolarity in patients treated for a major depressive disorder
title_short Screening for a false unipolarity in patients treated for a major depressive disorder
title_sort screening for a false unipolarity in patients treated for a major depressive disorder
topic HCL-20
bipolar depression
bipolar II disorder
hypomania
url https://www.cambridge.org/core/product/identifier/S0924933821005332/type/journal_article
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