Memantine Disrupts Motor Coordination through Anxiety-like Behavior in CD1 Mice

Memantine Disrupts Motor Coordination through Anxiety-like Behavior in CD1 Mice

Memantine is an FDA approved drug for the treatment of Alzheimer’s disease. It reduces neurodegeneration in the hippocampus and cerebral cortex through the inhibition of extrasynaptic NMDA receptors in patients and mouse models. Potentially, it could prevent neurodegeneration in other brain areas an...

Full description

Bibliographic Details
Main Authors: Anton N. Shuvaev, Olga S. Belozor, Oleg I. Mozhei, Aleksandra G. Mileiko, Ludmila D. Mosina, Irina V. Laletina, Ilia G. Mikhailov, Yana V. Fritsler, Andrey N. Shuvaev, Anja G. Teschemacher, Sergey Kasparov
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Brain Sciences
Subjects:
ataxia
memantine
anxiety
rotarod
Online Access:https://www.mdpi.com/2076-3425/12/4/495

Similar Items

Similar Items