MALT Lymphoma occurring in the maxillofacial region: A review of the literature and case report
Introduction: Mucosa-associated lymphoid tissue (MALT) lymphoma is a non-Hodgkin Lymphoma (NHL) localized all along the aerodigestive tract. The aim of this report is to present the case of a patient with MALT lymphoma in soft palate treated in our department. Case report: Case of a 26-year-old fema...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2017-09-01
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| Series: | Oral and Maxillofacial Surgery Cases |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214541917300160 |
| _version_ | 1811234191150415872 |
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| author | Francisco Merino Cristina Vázquez Martinez Ignacio Zubillaga Gregorio Sánchez Aniceto Claudio Ballestín |
| author_facet | Francisco Merino Cristina Vázquez Martinez Ignacio Zubillaga Gregorio Sánchez Aniceto Claudio Ballestín |
| author_sort | Francisco Merino |
| collection | DOAJ |
| description | Introduction: Mucosa-associated lymphoid tissue (MALT) lymphoma is a non-Hodgkin Lymphoma (NHL) localized all along the aerodigestive tract. The aim of this report is to present the case of a patient with MALT lymphoma in soft palate treated in our department.
Case report: Case of a 26-year-old female who visited our department. She presented a tumor in soft palate that she reported a year ago. A biopsy was performed with the diagnosis of a Low-B-grade MALT lymphoma type. Due to the low initial stage of the lesion the haematologist decided to start monotherapy with Rituximab. The therapy was changed to R-Bendamustine. At present and after two years since diagnosed (May, 2015–February, 2017), the patient is disease-free.
Discussion: The MALT lymphoma constitute 8% of the NHL. Progression to aggressive lymphoma is rare, occurring in under 10% of cases. Tumors are sensitive to radiotherapy and local treatment, both options can be followed by a prolonged disease-free period.
The optimal treatment of MALT Lymphoma has not been agreed yet.
Conclusion: MALT lymphoma is a rare disease in maxillofacial area, with tendency to remain in the original location for long periods. The optimal treatment of MALT Lymphoma has not been agreed yet. Due to persistent disease and concomitant Sjögren’s syndrome, in our case it was agreed that combination of Rituximab with other chemotherapy agents was indicated, with a good response. |
| first_indexed | 2024-04-12T11:32:29Z |
| format | Article |
| id | doaj.art-d1c53bc7a77540cab82366c17dd107fa |
| institution | Directory Open Access Journal |
| issn | 2214-5419 |
| language | English |
| last_indexed | 2024-04-12T11:32:29Z |
| publishDate | 2017-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Oral and Maxillofacial Surgery Cases |
| spelling | doaj.art-d1c53bc7a77540cab82366c17dd107fa2022-12-22T03:34:57ZengElsevierOral and Maxillofacial Surgery Cases2214-54192017-09-0133707510.1016/j.omsc.2017.06.001MALT Lymphoma occurring in the maxillofacial region: A review of the literature and case reportFrancisco MerinoCristina Vázquez MartinezIgnacio ZubillagaGregorio Sánchez AnicetoClaudio BallestínIntroduction: Mucosa-associated lymphoid tissue (MALT) lymphoma is a non-Hodgkin Lymphoma (NHL) localized all along the aerodigestive tract. The aim of this report is to present the case of a patient with MALT lymphoma in soft palate treated in our department. Case report: Case of a 26-year-old female who visited our department. She presented a tumor in soft palate that she reported a year ago. A biopsy was performed with the diagnosis of a Low-B-grade MALT lymphoma type. Due to the low initial stage of the lesion the haematologist decided to start monotherapy with Rituximab. The therapy was changed to R-Bendamustine. At present and after two years since diagnosed (May, 2015–February, 2017), the patient is disease-free. Discussion: The MALT lymphoma constitute 8% of the NHL. Progression to aggressive lymphoma is rare, occurring in under 10% of cases. Tumors are sensitive to radiotherapy and local treatment, both options can be followed by a prolonged disease-free period. The optimal treatment of MALT Lymphoma has not been agreed yet. Conclusion: MALT lymphoma is a rare disease in maxillofacial area, with tendency to remain in the original location for long periods. The optimal treatment of MALT Lymphoma has not been agreed yet. Due to persistent disease and concomitant Sjögren’s syndrome, in our case it was agreed that combination of Rituximab with other chemotherapy agents was indicated, with a good response.http://www.sciencedirect.com/science/article/pii/S2214541917300160MALT LymphomaOral malignant neoplasmRituximab |
| spellingShingle | Francisco Merino Cristina Vázquez Martinez Ignacio Zubillaga Gregorio Sánchez Aniceto Claudio Ballestín MALT Lymphoma occurring in the maxillofacial region: A review of the literature and case report Oral and Maxillofacial Surgery Cases MALT Lymphoma Oral malignant neoplasm Rituximab |
| title | MALT Lymphoma occurring in the maxillofacial region: A review of the literature and case report |
| title_full | MALT Lymphoma occurring in the maxillofacial region: A review of the literature and case report |
| title_fullStr | MALT Lymphoma occurring in the maxillofacial region: A review of the literature and case report |
| title_full_unstemmed | MALT Lymphoma occurring in the maxillofacial region: A review of the literature and case report |
| title_short | MALT Lymphoma occurring in the maxillofacial region: A review of the literature and case report |
| title_sort | malt lymphoma occurring in the maxillofacial region a review of the literature and case report |
| topic | MALT Lymphoma Oral malignant neoplasm Rituximab |
| url | http://www.sciencedirect.com/science/article/pii/S2214541917300160 |
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