The influence of hydrocortisone on cellular defence mechanisms of Biomphalaria glabrata
Since the internal defense system of mollusks consists of cellular and humoral mechanisms, we examined the role of hydrocortisone in mollusks defense cells and the influence of this steroid on the development of Schistosoma mansoni in its intermediary host. Hydrocortisone had an immunosuppressive ac...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Fundação Oswaldo Cruz (FIOCRUZ)
2002-09-01
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| Series: | Memorias do Instituto Oswaldo Cruz |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762002000600024 |
| _version_ | 1797704756304543744 |
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| author | Deborah Regina Serrano Eliana Maria Zanotti-Magalhães Luiz Augusto Magalhães José Ferreira de Carvalho |
| author_facet | Deborah Regina Serrano Eliana Maria Zanotti-Magalhães Luiz Augusto Magalhães José Ferreira de Carvalho |
| author_sort | Deborah Regina Serrano |
| collection | DOAJ |
| description | Since the internal defense system of mollusks consists of cellular and humoral mechanisms, we examined the role of hydrocortisone in mollusks defense cells and the influence of this steroid on the development of Schistosoma mansoni in its intermediary host. Hydrocortisone had an immunosuppressive action in Biomphalaria glabrata, as reflected in the reduced number of defense cells and the altered cell physiology. Histopathological analysis showed that hydrocortisone facilitated the intramolluscan development of S. mansoni, by reducing the extent of the inflammatory response, seen as a greater number of viable sporocysts with no surrounding hemocytes. |
| first_indexed | 2024-03-12T05:25:07Z |
| format | Article |
| id | doaj.art-d1c7372cd0e64fe2ba83452f72a1e4f8 |
| institution | Directory Open Access Journal |
| issn | 0074-0276 1678-8060 |
| language | English |
| last_indexed | 2024-03-12T05:25:07Z |
| publishDate | 2002-09-01 |
| publisher | Fundação Oswaldo Cruz (FIOCRUZ) |
| record_format | Article |
| series | Memorias do Instituto Oswaldo Cruz |
| spelling | doaj.art-d1c7372cd0e64fe2ba83452f72a1e4f82023-09-03T07:25:00ZengFundação Oswaldo Cruz (FIOCRUZ)Memorias do Instituto Oswaldo Cruz0074-02761678-80602002-09-0197688188510.1590/S0074-02762002000600024The influence of hydrocortisone on cellular defence mechanisms of Biomphalaria glabrataDeborah Regina SerranoEliana Maria Zanotti-MagalhãesLuiz Augusto MagalhãesJosé Ferreira de CarvalhoSince the internal defense system of mollusks consists of cellular and humoral mechanisms, we examined the role of hydrocortisone in mollusks defense cells and the influence of this steroid on the development of Schistosoma mansoni in its intermediary host. Hydrocortisone had an immunosuppressive action in Biomphalaria glabrata, as reflected in the reduced number of defense cells and the altered cell physiology. Histopathological analysis showed that hydrocortisone facilitated the intramolluscan development of S. mansoni, by reducing the extent of the inflammatory response, seen as a greater number of viable sporocysts with no surrounding hemocytes.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762002000600024Schistosoma mansoniBiomphalaria glabratahydrocortisonesporocysthemocyte reaction |
| spellingShingle | Deborah Regina Serrano Eliana Maria Zanotti-Magalhães Luiz Augusto Magalhães José Ferreira de Carvalho The influence of hydrocortisone on cellular defence mechanisms of Biomphalaria glabrata Memorias do Instituto Oswaldo Cruz Schistosoma mansoni Biomphalaria glabrata hydrocortisone sporocyst hemocyte reaction |
| title | The influence of hydrocortisone on cellular defence mechanisms of Biomphalaria glabrata |
| title_full | The influence of hydrocortisone on cellular defence mechanisms of Biomphalaria glabrata |
| title_fullStr | The influence of hydrocortisone on cellular defence mechanisms of Biomphalaria glabrata |
| title_full_unstemmed | The influence of hydrocortisone on cellular defence mechanisms of Biomphalaria glabrata |
| title_short | The influence of hydrocortisone on cellular defence mechanisms of Biomphalaria glabrata |
| title_sort | influence of hydrocortisone on cellular defence mechanisms of biomphalaria glabrata |
| topic | Schistosoma mansoni Biomphalaria glabrata hydrocortisone sporocyst hemocyte reaction |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762002000600024 |
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