Factors Affecting the Prevalence of Gastro-oesophageal Reflux in Childhood Corrosive Oesophageal Strictures
Background: Gastro-oesophageal reflux may accompany the corrosive oesophageal damage caused by the ingestion of corrosive substances and affect its treatment. The factors that affect the development of reflux in these cases and their effects on treatment still remain unclear. Aims: Our aim is to...
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| Format: | Article |
| Language: | English |
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Galenos Publishing House
2014-06-01
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| Series: | Balkan Medical Journal |
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| Online Access: | http://balkanmedicaljournal.org/text.php?lang=en&id=306 |
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| author | Serdar H. İskit Murat Alkan Ünal Zorludemir Zerrin Özçelik Selcan Türker |
| author_facet | Serdar H. İskit Murat Alkan Ünal Zorludemir Zerrin Özçelik Selcan Türker |
| author_sort | Serdar H. İskit |
| collection | DOAJ |
| description | Background: Gastro-oesophageal reflux may accompany the corrosive oesophageal damage caused by the ingestion of corrosive substances and affect its treatment. The factors that affect the development of reflux in these cases and their effects on treatment still remain unclear.
Aims: Our aim is to investigate the prevalence of gastro-oesophageal reflux in children with corrosive oesophageal strictures, the risk factors affecting this prevalence and the effects of gastro-oesophageal reflux on treatment.
Study Design: Case-control study.
Methods: We enrolled 52 patients with oesophageal stricture due to corrosive substance ingestion who were referred to our clinic between 2003 and 2010. Groups, which were determined according to the presence of gastro-oesophageal reflux (GER), were compared with each other in terms of clinical findings, results of examination methods, characteristics of the stricture and success of the treatment.
Results: The total number of patients in our study was 52; 30 of them were male and 22 of them were female. The mean age of our study population was 4.2±2.88 years. Thirty-three patients had gastro-oesophageal reflux (63.5%). Patients who had strictures caused by the ingestion of alkali substances were 1.6-times more likely to have reflux. There were no differences between patients with or without reflux in terms of number and localisation of strictures. Mean distance of stricture was longer in patients with reflux (3.7±1.8 cm) than in patients without (2.2±1.0 cm) (p<0.005). Only one patient among 17 who had a long stricture (≥4 cm) did not suffer from reflux. Patients with long stricture were 1.9-times more likely to have reflux. Dilatation treatment was successful in 69.6% of patients with reflux and in 78.9% of patients without. The mean treatment period was 8.41±6.1 months in patients with reflux and 8.21±8.4 months in the other group. There was no significant difference between groups in terms of frequency of dilatation and dilator diameters (p>0.05).
Conclusion: Corrosive oesophageal stricture was usually accompanied by gastro-oesophageal reflux and the length of stricture is an important risk factor. Negative effects of reflux over dilatation treatment have not yet been demonstrated in the short-term. Nevertheless, this frequent rate of reflux may eventually increase the risk of oesophagitis and Barrett’s oesophagus; therefore, we suggest that these effects should be prospectively evaluated in a large number of patients and these patients should be followed-up routinely in terms of the long-term effects of reflux. |
| first_indexed | 2024-04-10T11:00:22Z |
| format | Article |
| id | doaj.art-d1c874fa3c2649a7882b7260bc9d321b |
| institution | Directory Open Access Journal |
| issn | 2146-3123 2146-3131 |
| language | English |
| last_indexed | 2024-04-10T11:00:22Z |
| publishDate | 2014-06-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Balkan Medical Journal |
| spelling | doaj.art-d1c874fa3c2649a7882b7260bc9d321b2023-02-15T16:19:43ZengGalenos Publishing HouseBalkan Medical Journal2146-31232146-31312014-06-0131213714210.5152/balkanmedj.2014.13276Factors Affecting the Prevalence of Gastro-oesophageal Reflux in Childhood Corrosive Oesophageal StricturesSerdar H. İskit0Murat Alkan1Ünal Zorludemir2Zerrin Özçelik3Selcan Türker4Department of Pediatric Surgery, Çukurova University Faculty of Medicine, Adana, TurkeyDepartment of Pediatric Surgery, Çukurova University Faculty of Medicine, Adana, TurkeyDepartment of Pediatric Surgery, Çukurova University Faculty of Medicine, Adana, TurkeyDepartment of Pediatric Surgery, Numune Hospital, Adana, TurkeyDepartment of Pediatric Surgery Unit, Şehit Kamil Hospital, Gaziantep, TurkeyBackground: Gastro-oesophageal reflux may accompany the corrosive oesophageal damage caused by the ingestion of corrosive substances and affect its treatment. The factors that affect the development of reflux in these cases and their effects on treatment still remain unclear. Aims: Our aim is to investigate the prevalence of gastro-oesophageal reflux in children with corrosive oesophageal strictures, the risk factors affecting this prevalence and the effects of gastro-oesophageal reflux on treatment. Study Design: Case-control study. Methods: We enrolled 52 patients with oesophageal stricture due to corrosive substance ingestion who were referred to our clinic between 2003 and 2010. Groups, which were determined according to the presence of gastro-oesophageal reflux (GER), were compared with each other in terms of clinical findings, results of examination methods, characteristics of the stricture and success of the treatment. Results: The total number of patients in our study was 52; 30 of them were male and 22 of them were female. The mean age of our study population was 4.2±2.88 years. Thirty-three patients had gastro-oesophageal reflux (63.5%). Patients who had strictures caused by the ingestion of alkali substances were 1.6-times more likely to have reflux. There were no differences between patients with or without reflux in terms of number and localisation of strictures. Mean distance of stricture was longer in patients with reflux (3.7±1.8 cm) than in patients without (2.2±1.0 cm) (p<0.005). Only one patient among 17 who had a long stricture (≥4 cm) did not suffer from reflux. Patients with long stricture were 1.9-times more likely to have reflux. Dilatation treatment was successful in 69.6% of patients with reflux and in 78.9% of patients without. The mean treatment period was 8.41±6.1 months in patients with reflux and 8.21±8.4 months in the other group. There was no significant difference between groups in terms of frequency of dilatation and dilator diameters (p>0.05). Conclusion: Corrosive oesophageal stricture was usually accompanied by gastro-oesophageal reflux and the length of stricture is an important risk factor. Negative effects of reflux over dilatation treatment have not yet been demonstrated in the short-term. Nevertheless, this frequent rate of reflux may eventually increase the risk of oesophagitis and Barrett’s oesophagus; therefore, we suggest that these effects should be prospectively evaluated in a large number of patients and these patients should be followed-up routinely in terms of the long-term effects of reflux.http://balkanmedicaljournal.org/text.php?lang=en&id=306Corrosive oesophageal burnsgastro-oesophageal refluxoesophageal pH monitoringoesophagitis |
| spellingShingle | Serdar H. İskit Murat Alkan Ünal Zorludemir Zerrin Özçelik Selcan Türker Factors Affecting the Prevalence of Gastro-oesophageal Reflux in Childhood Corrosive Oesophageal Strictures Balkan Medical Journal Corrosive oesophageal burns gastro-oesophageal reflux oesophageal pH monitoring oesophagitis |
| title | Factors Affecting the Prevalence of Gastro-oesophageal Reflux in Childhood Corrosive Oesophageal Strictures |
| title_full | Factors Affecting the Prevalence of Gastro-oesophageal Reflux in Childhood Corrosive Oesophageal Strictures |
| title_fullStr | Factors Affecting the Prevalence of Gastro-oesophageal Reflux in Childhood Corrosive Oesophageal Strictures |
| title_full_unstemmed | Factors Affecting the Prevalence of Gastro-oesophageal Reflux in Childhood Corrosive Oesophageal Strictures |
| title_short | Factors Affecting the Prevalence of Gastro-oesophageal Reflux in Childhood Corrosive Oesophageal Strictures |
| title_sort | factors affecting the prevalence of gastro oesophageal reflux in childhood corrosive oesophageal strictures |
| topic | Corrosive oesophageal burns gastro-oesophageal reflux oesophageal pH monitoring oesophagitis |
| url | http://balkanmedicaljournal.org/text.php?lang=en&id=306 |
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