Structure of the transporter associated with antigen processing trapped by herpes simplex virus

The transporter associated with antigen processing (TAP) is an ATP-binding cassette (ABC) transporter essential to cellular immunity against viral infection. Some persistent viruses have evolved strategies to inhibit TAP so that they may go undetected by the immune system. The herpes simplex virus f...

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Bibliographic Details
Main Authors: Michael L Oldham, Nikolaus Grigorieff, Jue Chen
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-12-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/21829