An Immunodominant Region of the Envelope Glycoprotein of Small Ruminant Lentiviruses May Function as Decoy Antigen

An Immunodominant Region of the Envelope Glycoprotein of Small Ruminant Lentiviruses May Function as Decoy Antigen

(1) Background: Small ruminant lentiviruses (SRLV) persist in infected goats that mount a strong humoral immune response characterized by low neutralizing titers. In this study, we characterized the antibody response to SU5, a variable, immunodominant epitope of the envelope glycoprotein of SRLV. We...

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Bibliographic Details
Main Authors: Marie-Luise Zahno, Giuseppe Bertoni
Format: Article
Language:English
Published: MDPI AG 2018-05-01
Series:Viruses
Subjects:
caprine arthritis encephalitis virus CAEV
small ruminant lentiviruses SRLV
decoy antigen
immunodominant epitope
escape
neutralizing antibody
lentivirus
original antigenic sin
Online Access:http://www.mdpi.com/1999-4915/10/5/231

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http://www.mdpi.com/1999-4915/10/5/231

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