Early Enhancement of Neuroplasticity Index, the Ratio of Serum Brain-Derived Neurotrophic Factor Level to HAMD-24 Score, in Predicting the Long-Term Antidepressant Efficacy

Early Enhancement of Neuroplasticity Index, the Ratio of Serum Brain-Derived Neurotrophic Factor Level to HAMD-24 Score, in Predicting the Long-Term Antidepressant Efficacy

Background: Current mainstream treatment of major depressive disorder (MDD) has a disadvantage in delayed onset of efficacy, making detection of early signatures predicative of the long-term treatment efficacy urgent.Methods: MDD patients were scored with HAMD-24 and serum brain-derived neurotrophic...

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Bibliographic Details
Main Authors: Yuxuan Zhang, Bo Cui, Tianyu Wang, Yan Lu, Zhenlin Chen, Zhilu Zou, Jinlin Miao, Xiuli Zhao, Yonggui Yuan, Haosen Wang, Gang Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Yueju pill
BDNF
antidepressant efficacy
prediction
neuroplasticity index
Online Access:https://www.frontiersin.org/articles/10.3389/fnbeh.2021.712445/full

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