The analysis on 12 cases of acute disseminated encephalomyelitis
Objective To study the clinical features and treatment of acute disseminated encephalomyelitis (ADEM). Methods All patients admitted with ADEM during May 1990 to Dec 2010 were included in the study. Clinical data of 12 cases with ADEM were reviewed and analysed. The diagnosis of ADEM was made based...
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| Format: | Article |
| Language: | English |
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Tianjin Huanhu Hospital
2012-04-01
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| Series: | Chinese Journal of Contemporary Neurology and Neurosurgery |
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| Online Access: | http://www.cjcnn.org/index.php/cjcnn/article/view/144 |
| _version_ | 1819025584284499968 |
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| author | Zhao⁃hui SONG Rui⁃jin WANG Shan⁃chao ZHANG Lei LIU Fei⁃fei DAI Jia⁃wei WANG |
| author_facet | Zhao⁃hui SONG Rui⁃jin WANG Shan⁃chao ZHANG Lei LIU Fei⁃fei DAI Jia⁃wei WANG |
| author_sort | Zhao⁃hui SONG |
| collection | DOAJ |
| description | Objective To study the clinical features and treatment of acute disseminated encephalomyelitis (ADEM). Methods All patients admitted with ADEM during May 1990 to Dec 2010 were included in the study. Clinical data of 12 cases with ADEM were reviewed and analysed. The diagnosis of ADEM was made based on the clinical presentation, suggestive MRI and auxiliary examination findings. All patients were treated with intravenous steroids or immunoglobulins (IVIg). Results The sample consisted of 10 men and 2 women. The oldest patient was 69 years old and the youngest was 6 years old. Six patients had definite upper respiratory tract infection preceded the onset of neurological symptoms, 3 patients had non⁃specific fever, 1 patient had measles vaccination, 1 patient had measles prior to the onset 4 months ago. No preceding illness and vaccination occurred in 1 patient. The common presenting symptoms were fever, nausea, vomiting, headache. Neurological manifestations included cranial nerve involvement (the abducent nerve was the most common cranial nerve involved), paralysis (include hemiplegia, quadriplegia, paraplegia), altered sensorium, bladder involvement (both incontinence and retention), meningeal irrigation sign and conscious disturbance. Conclusion Despite the serious manifestation, ADEM in patient has good immediate outcome. Early diagnosis and treatment should be emphasized.
DOI：10.3969/j.issn.1672⁃6731.2012.02.015 |
| first_indexed | 2024-12-21T05:13:00Z |
| format | Article |
| id | doaj.art-d1ceafd4bd044c268f45d8c0f775dc3a |
| institution | Directory Open Access Journal |
| issn | 1672-6731 |
| language | English |
| last_indexed | 2024-12-21T05:13:00Z |
| publishDate | 2012-04-01 |
| publisher | Tianjin Huanhu Hospital |
| record_format | Article |
| series | Chinese Journal of Contemporary Neurology and Neurosurgery |
| spelling | doaj.art-d1ceafd4bd044c268f45d8c0f775dc3a2022-12-21T19:15:00ZengTianjin Huanhu HospitalChinese Journal of Contemporary Neurology and Neurosurgery1672-67312012-04-01122166170143The analysis on 12 cases of acute disseminated encephalomyelitisZhao⁃hui SONGRui⁃jin WANGShan⁃chao ZHANGLei LIUFei⁃fei DAIJia⁃wei WANGObjective To study the clinical features and treatment of acute disseminated encephalomyelitis (ADEM). Methods All patients admitted with ADEM during May 1990 to Dec 2010 were included in the study. Clinical data of 12 cases with ADEM were reviewed and analysed. The diagnosis of ADEM was made based on the clinical presentation, suggestive MRI and auxiliary examination findings. All patients were treated with intravenous steroids or immunoglobulins (IVIg). Results The sample consisted of 10 men and 2 women. The oldest patient was 69 years old and the youngest was 6 years old. Six patients had definite upper respiratory tract infection preceded the onset of neurological symptoms, 3 patients had non⁃specific fever, 1 patient had measles vaccination, 1 patient had measles prior to the onset 4 months ago. No preceding illness and vaccination occurred in 1 patient. The common presenting symptoms were fever, nausea, vomiting, headache. Neurological manifestations included cranial nerve involvement (the abducent nerve was the most common cranial nerve involved), paralysis (include hemiplegia, quadriplegia, paraplegia), altered sensorium, bladder involvement (both incontinence and retention), meningeal irrigation sign and conscious disturbance. Conclusion Despite the serious manifestation, ADEM in patient has good immediate outcome. Early diagnosis and treatment should be emphasized. DOI：10.3969/j.issn.1672⁃6731.2012.02.015http://www.cjcnn.org/index.php/cjcnn/article/view/144Encephalomyelitis, acute disseminatedDiagnosis |
| spellingShingle | Zhao⁃hui SONG Rui⁃jin WANG Shan⁃chao ZHANG Lei LIU Fei⁃fei DAI Jia⁃wei WANG The analysis on 12 cases of acute disseminated encephalomyelitis Chinese Journal of Contemporary Neurology and Neurosurgery Encephalomyelitis, acute disseminated Diagnosis |
| title | The analysis on 12 cases of acute disseminated encephalomyelitis |
| title_full | The analysis on 12 cases of acute disseminated encephalomyelitis |
| title_fullStr | The analysis on 12 cases of acute disseminated encephalomyelitis |
| title_full_unstemmed | The analysis on 12 cases of acute disseminated encephalomyelitis |
| title_short | The analysis on 12 cases of acute disseminated encephalomyelitis |
| title_sort | analysis on 12 cases of acute disseminated encephalomyelitis |
| topic | Encephalomyelitis, acute disseminated Diagnosis |
| url | http://www.cjcnn.org/index.php/cjcnn/article/view/144 |
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