CRISPR/Cas9: implications for modeling and therapy of neurodegenerative diseases

CRISPR/Cas9: implications for modeling and therapy of neurodegenerative diseases

CRISPR/Cas9 is now used widely to genetically modify the genomes of various species. The ability of CRISPR/Cas9 to delete DNA sequences and correct DNA mutations opens up a new avenue to treat genetic diseases that are caused by DNA mutations. In this review, we describe the advantages of using CRIS...

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Bibliographic Details
Main Authors: Weili eYang, Zhuchi eTu, Qiang eSun, Xiao-Jiang eLi
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-04-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Gene Therapy
Neurodegenerative Diseases
Animal Models
CRISPR/Cas9
Genetic mutations
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2016.00030/full

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