Neuroendocrine cancer of the prostate. Two case reports
Background: Neuroendocrine cancer of the prostate can present in diverse clinical pictures, potentially hampering the diagnosis and probably leading to underdiagnosis. Methods: Two cases are presented corresponding respectively to two forms of the disease: de novo neuroendocrine cancer and dediffere...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MRE Press
2022-03-01
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| Series: | Journal of Men's Health |
| Subjects: | |
| Online Access: | https://www.imrpress.com/journal/JOMH/18/3/10.31083/j.jomh1803065 |
| _version_ | 1827359354838319104 |
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| author | Tamás Kullmann Szigeti András Kránitz Noémi Szepesváry Zsolt |
| author_facet | Tamás Kullmann Szigeti András Kránitz Noémi Szepesváry Zsolt |
| author_sort | Tamás Kullmann |
| collection | DOAJ |
| description | Background: Neuroendocrine cancer of the prostate can present in diverse clinical pictures, potentially hampering the diagnosis and probably leading to underdiagnosis. Methods: Two cases are presented corresponding respectively to two forms of the disease: de novo neuroendocrine cancer and dedifferenciation of an adenocarcinoma of the prostate to neuroendocrine cancer under long term luteinising hormone releasing hormone (LHRH) agonist treatment. Results: Suspicion of neuroendocrine cancer may be raised in prostate cancer patients presenting either clinical or radiological metastatic progression without prostate specific antigen (PSA) rise, or relatively extended metastatic disease right at diagnosis associated to relatively low PSA, yet any non-pulmonary visceral metastases. Neuroendocrine cancer of the prostate can also turn out to be the origin of an adenocarcinoma of unknown primary. Conclusion: In case these considerations are respected the risk of missing the correct diagnosis of a neuroendocrine cancer of the prostate may be minimised. |
| first_indexed | 2024-03-08T06:26:45Z |
| format | Article |
| id | doaj.art-d1dcda8904234f30a658d747657eb766 |
| institution | Directory Open Access Journal |
| issn | 1875-6859 |
| language | English |
| last_indexed | 2024-03-08T06:26:45Z |
| publishDate | 2022-03-01 |
| publisher | MRE Press |
| record_format | Article |
| series | Journal of Men's Health |
| spelling | doaj.art-d1dcda8904234f30a658d747657eb7662024-02-03T14:44:29ZengMRE PressJournal of Men's Health1875-68592022-03-0118306510.31083/j.jomh1803065S1875-6867(22)00297-4Neuroendocrine cancer of the prostate. Two case reportsTamás Kullmann0Szigeti András1Kránitz Noémi2Szepesváry Zsolt3Department of Oncoradiology, Petz Aladár Hospital, 9024 Győr, HungaryDepartment of Oncoradiology, Petz Aladár Hospital, 9024 Győr, HungaryDepartment of Pathology, Petz Aladár Hospital, 9024 Győr, HungaryDepartment of Urology, Petz Aladár Hospital, 9024 Győr, HungaryBackground: Neuroendocrine cancer of the prostate can present in diverse clinical pictures, potentially hampering the diagnosis and probably leading to underdiagnosis. Methods: Two cases are presented corresponding respectively to two forms of the disease: de novo neuroendocrine cancer and dedifferenciation of an adenocarcinoma of the prostate to neuroendocrine cancer under long term luteinising hormone releasing hormone (LHRH) agonist treatment. Results: Suspicion of neuroendocrine cancer may be raised in prostate cancer patients presenting either clinical or radiological metastatic progression without prostate specific antigen (PSA) rise, or relatively extended metastatic disease right at diagnosis associated to relatively low PSA, yet any non-pulmonary visceral metastases. Neuroendocrine cancer of the prostate can also turn out to be the origin of an adenocarcinoma of unknown primary. Conclusion: In case these considerations are respected the risk of missing the correct diagnosis of a neuroendocrine cancer of the prostate may be minimised.https://www.imrpress.com/journal/JOMH/18/3/10.31083/j.jomh1803065neuroendocrine cancerprostate cancerserum markersynaptophysinnse |
| spellingShingle | Tamás Kullmann Szigeti András Kránitz Noémi Szepesváry Zsolt Neuroendocrine cancer of the prostate. Two case reports Journal of Men's Health neuroendocrine cancer prostate cancer serum marker synaptophysin nse |
| title | Neuroendocrine cancer of the prostate. Two case reports |
| title_full | Neuroendocrine cancer of the prostate. Two case reports |
| title_fullStr | Neuroendocrine cancer of the prostate. Two case reports |
| title_full_unstemmed | Neuroendocrine cancer of the prostate. Two case reports |
| title_short | Neuroendocrine cancer of the prostate. Two case reports |
| title_sort | neuroendocrine cancer of the prostate two case reports |
| topic | neuroendocrine cancer prostate cancer serum marker synaptophysin nse |
| url | https://www.imrpress.com/journal/JOMH/18/3/10.31083/j.jomh1803065 |
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