ACTH in invertebrates: a molecule for all seasons
In vertebrate and invertebrate models, adrenocorticotropic hormone (ACTH) belongs to the melanocortin group of related peptides, which share a common precursor, pro-opiomelanocortin (POMC). Functional experiments indicate that in invertebrates, ACTH plays a major role in several biological functions...
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| Format: | Article |
| Language: | English |
| Published: |
University of Modena and Reggio Emilia
2016-01-01
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| Series: | Invertebrate Survival Journal |
| Subjects: | |
| Online Access: | https://isj02.unimore.it/index.php/ISJ/article/view/374 |
| _version_ | 1819279742795251712 |
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| author | D Malagoli E Ottaviani |
| author_facet | D Malagoli E Ottaviani |
| author_sort | D Malagoli |
| collection | DOAJ |
| description | In vertebrate and invertebrate models, adrenocorticotropic hormone (ACTH) belongs to the melanocortin group of related peptides, which share a common precursor, pro-opiomelanocortin (POMC). Functional experiments indicate that in invertebrates, ACTH plays a major role in several biological functions. ACTH, whose effects have been conserved during evolution more than its amino acidic sequence, is, directly or indirectly, able to contrast agents that perturb a body’s homeostasis. Here we review evidence highlighting the involvement of ACTH and ACTH-like molecules in the response of invertebrate models versus immune, environmental and parasitic challenges. |
| first_indexed | 2024-12-24T00:32:45Z |
| format | Article |
| id | doaj.art-d1ecb5394c1843d291bb1232a62d8ada |
| institution | Directory Open Access Journal |
| issn | 1824-307X |
| language | English |
| last_indexed | 2024-12-24T00:32:45Z |
| publishDate | 2016-01-01 |
| publisher | University of Modena and Reggio Emilia |
| record_format | Article |
| series | Invertebrate Survival Journal |
| spelling | doaj.art-d1ecb5394c1843d291bb1232a62d8ada2022-12-21T17:24:12ZengUniversity of Modena and Reggio EmiliaInvertebrate Survival Journal1824-307X2016-01-01131ACTH in invertebrates: a molecule for all seasonsD Malagoli0E Ottaviani1Department of Life Sciences, University of Modena and Reggio Emilia, via Campi, 213/D, 41125 Modena, ItalyDepartment of Life Sciences, University of Modena and Reggio Emilia, via Campi, 213/D, 41125 Modena, ItalyIn vertebrate and invertebrate models, adrenocorticotropic hormone (ACTH) belongs to the melanocortin group of related peptides, which share a common precursor, pro-opiomelanocortin (POMC). Functional experiments indicate that in invertebrates, ACTH plays a major role in several biological functions. ACTH, whose effects have been conserved during evolution more than its amino acidic sequence, is, directly or indirectly, able to contrast agents that perturb a body’s homeostasis. Here we review evidence highlighting the involvement of ACTH and ACTH-like molecules in the response of invertebrate models versus immune, environmental and parasitic challenges.https://isj02.unimore.it/index.php/ISJ/article/view/374ACTHinvertebratesimmunomodulationstress responseparasitization |
| spellingShingle | D Malagoli E Ottaviani ACTH in invertebrates: a molecule for all seasons Invertebrate Survival Journal ACTH invertebrates immunomodulation stress response parasitization |
| title | ACTH in invertebrates: a molecule for all seasons |
| title_full | ACTH in invertebrates: a molecule for all seasons |
| title_fullStr | ACTH in invertebrates: a molecule for all seasons |
| title_full_unstemmed | ACTH in invertebrates: a molecule for all seasons |
| title_short | ACTH in invertebrates: a molecule for all seasons |
| title_sort | acth in invertebrates a molecule for all seasons |
| topic | ACTH invertebrates immunomodulation stress response parasitization |
| url | https://isj02.unimore.it/index.php/ISJ/article/view/374 |
| work_keys_str_mv | AT dmalagoli acthininvertebratesamoleculeforallseasons AT eottaviani acthininvertebratesamoleculeforallseasons |