Immune Microenvironment of Brain Metastases—Are Microglia and Other Brain Macrophages Little Helpers?

Immune Microenvironment of Brain Metastases—Are Microglia and Other Brain Macrophages Little Helpers?

Brain metastases are common intracranial neoplasms and their frequency increases with prolonged survival of cancer patients. New pharmaceuticals targeting oncogenic kinases and immune checkpoint inhibitors augment both overall and progression-free survival in patients with brain metastases, but are...

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Bibliographic Details
Main Authors: Hua You, Szymon Baluszek, Bozena Kaminska
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Immunology
Subjects:
neuro-oncology
brain metastases
tumor microenvironment
immune infiltrates
microglia
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01941/full

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