Chronic p38 mitogen-activated protein kinase inhibition improves vascular function and remodeling in angiotensin II-dependent hypertension

Chronic p38 mitogen-activated protein kinase inhibition improves vascular function and remodeling in angiotensin II-dependent hypertension

Introduction: An excess of angiotensin II (Ang II) causes hypertension and vascular injury. Activation of mitogen-activated protein kinase p38 (p38-MAPK) plays a substantial role in Ang II-dependent organ damage. Recently, we showed that p38-MAPK activation regulates the pressor response to Ang II....

Full description

Bibliographic Details
Main Authors: SA Potthoff, S Stamer, K Grave, E Königshausen, SH Sivritas, M Thieme, Y Mori, M Woznowski, LC Rump, J Stegbauer
Format: Article
Language:English
Published: SAGE Publications 2016-07-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.1177/1470320316653284

Similar Items

Similar Items