Association Between Life's Simple 7 and Noncardiovascular Disease: The Multi‐Ethnic Study of Atherosclerosis
BackgroundThe American Heart Association introduced the Life's Simple 7 (LS7) metrics to assess and promote cardiovascular health. We examined the association between the LS7 metrics and noncardiovascular disease. Methods and ResultsWe studied 6506 men and women aged between 45 and 84 years, en...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2016-10-01
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| Series: | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
| Subjects: | |
| Online Access: | https://www.ahajournals.org/doi/10.1161/JAHA.116.003954 |
| _version_ | 1811332290948628480 |
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| author | Oluseye Ogunmoroti Norrina B. Allen Mary Cushman Erin D. Michos Tatjana Rundek Jamal S. Rana Ron Blankstein Roger S. Blumenthal Michael J. Blaha Emir Veledar Khurram Nasir |
| author_facet | Oluseye Ogunmoroti Norrina B. Allen Mary Cushman Erin D. Michos Tatjana Rundek Jamal S. Rana Ron Blankstein Roger S. Blumenthal Michael J. Blaha Emir Veledar Khurram Nasir |
| author_sort | Oluseye Ogunmoroti |
| collection | DOAJ |
| description | BackgroundThe American Heart Association introduced the Life's Simple 7 (LS7) metrics to assess and promote cardiovascular health. We examined the association between the LS7 metrics and noncardiovascular disease. Methods and ResultsWe studied 6506 men and women aged between 45 and 84 years, enrolled in the Multi‐Ethnic Study of Atherosclerosis. Median follow‐up time was 10.2 years. Each component of the LS7 metrics (smoking, body mass index, physical activity, diet, total cholesterol, blood pressure, and blood glucose) was assigned points, 0 indicates “poor” category; 1, “intermediate,” and 2, “ideal.” The LS7 score, ranged from 0 to 14, was created from the points and categorized as optimal (11–14), average (9–10), and inadequate (0–8). Hazard ratios and event rates per 1000 person‐years were calculated for outcomes based on self‐reported hospitalizations with the International Classification of Diseases, 9th Revision, diagnoses of cancer, chronic kidney disease, pneumonia, deep venous thromboembolism/pulmonary embolism, chronic obstructive pulmonary disease, dementia, and hip fracture. Analyses were adjusted for age, sex, race/ethnicity, income, and education. Overall, noncardiovascular disease event rates were lower with increasing LS7 scores. With the inadequate LS7 score as reference, an optimal score was associated with a decreased risk for noncardiovascular disease events. The hazard ratio for cancer was, 0.80 (0.64–0.98); chronic kidney disease, 0.38 (0.27–0.54); pneumonia, 0.57 (0.40–0.80); deep venous thromboembolism/pulmonary embolism, 0.52 (0.33–0.82), and chronic obstructive pulmonary disease, 0.51 (0.31–0.83). ConclusionsThe American Heart Association's LS7 score identified individuals who were vulnerable to multiple chronic nonvascular conditions. These results suggest that improving cardiovascular health will also reduce the burden of cancer and other chronic diseases. |
| first_indexed | 2024-04-13T16:34:35Z |
| format | Article |
| id | doaj.art-d1f57cac866a41f59a862351de953eb7 |
| institution | Directory Open Access Journal |
| issn | 2047-9980 |
| language | English |
| last_indexed | 2024-04-13T16:34:35Z |
| publishDate | 2016-10-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
| spelling | doaj.art-d1f57cac866a41f59a862351de953eb72022-12-22T02:39:28ZengWileyJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease2047-99802016-10-0151010.1161/JAHA.116.003954Association Between Life's Simple 7 and Noncardiovascular Disease: The Multi‐Ethnic Study of AtherosclerosisOluseye Ogunmoroti0Norrina B. Allen1Mary Cushman2Erin D. Michos3Tatjana Rundek4Jamal S. Rana5Ron Blankstein6Roger S. Blumenthal7Michael J. Blaha8Emir Veledar9Khurram Nasir10Center for Healthcare Advancement and Outcomes, Baptist Health South Florida, Miami, FLDepartment of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, ILDepartment of Medicine, Cardiovascular Research Institute, University of Vermont, Burlington, VTCiccarone Center for the Prevention of Heart Disease, Johns Hopkins University, Baltimore, MDDepartment of Neurology, Miller School of Medicine, University of Miami, FLDivision of Cardiology and Division of Research, Kaiser Permanente Northern California, Oakland, CADepartments of Medicine and Radiology, Brigham and Women's Hospital, Boston, MACiccarone Center for the Prevention of Heart Disease, Johns Hopkins University, Baltimore, MDCiccarone Center for the Prevention of Heart Disease, Johns Hopkins University, Baltimore, MDCenter for Healthcare Advancement and Outcomes, Baptist Health South Florida, Miami, FLCenter for Healthcare Advancement and Outcomes, Baptist Health South Florida, Miami, FLBackgroundThe American Heart Association introduced the Life's Simple 7 (LS7) metrics to assess and promote cardiovascular health. We examined the association between the LS7 metrics and noncardiovascular disease. Methods and ResultsWe studied 6506 men and women aged between 45 and 84 years, enrolled in the Multi‐Ethnic Study of Atherosclerosis. Median follow‐up time was 10.2 years. Each component of the LS7 metrics (smoking, body mass index, physical activity, diet, total cholesterol, blood pressure, and blood glucose) was assigned points, 0 indicates “poor” category; 1, “intermediate,” and 2, “ideal.” The LS7 score, ranged from 0 to 14, was created from the points and categorized as optimal (11–14), average (9–10), and inadequate (0–8). Hazard ratios and event rates per 1000 person‐years were calculated for outcomes based on self‐reported hospitalizations with the International Classification of Diseases, 9th Revision, diagnoses of cancer, chronic kidney disease, pneumonia, deep venous thromboembolism/pulmonary embolism, chronic obstructive pulmonary disease, dementia, and hip fracture. Analyses were adjusted for age, sex, race/ethnicity, income, and education. Overall, noncardiovascular disease event rates were lower with increasing LS7 scores. With the inadequate LS7 score as reference, an optimal score was associated with a decreased risk for noncardiovascular disease events. The hazard ratio for cancer was, 0.80 (0.64–0.98); chronic kidney disease, 0.38 (0.27–0.54); pneumonia, 0.57 (0.40–0.80); deep venous thromboembolism/pulmonary embolism, 0.52 (0.33–0.82), and chronic obstructive pulmonary disease, 0.51 (0.31–0.83). ConclusionsThe American Heart Association's LS7 score identified individuals who were vulnerable to multiple chronic nonvascular conditions. These results suggest that improving cardiovascular health will also reduce the burden of cancer and other chronic diseases.https://www.ahajournals.org/doi/10.1161/JAHA.116.003954epidemiologyLife's Simple 7preventionrisk factor |
| spellingShingle | Oluseye Ogunmoroti Norrina B. Allen Mary Cushman Erin D. Michos Tatjana Rundek Jamal S. Rana Ron Blankstein Roger S. Blumenthal Michael J. Blaha Emir Veledar Khurram Nasir Association Between Life's Simple 7 and Noncardiovascular Disease: The Multi‐Ethnic Study of Atherosclerosis Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease epidemiology Life's Simple 7 prevention risk factor |
| title | Association Between Life's Simple 7 and Noncardiovascular Disease: The Multi‐Ethnic Study of Atherosclerosis |
| title_full | Association Between Life's Simple 7 and Noncardiovascular Disease: The Multi‐Ethnic Study of Atherosclerosis |
| title_fullStr | Association Between Life's Simple 7 and Noncardiovascular Disease: The Multi‐Ethnic Study of Atherosclerosis |
| title_full_unstemmed | Association Between Life's Simple 7 and Noncardiovascular Disease: The Multi‐Ethnic Study of Atherosclerosis |
| title_short | Association Between Life's Simple 7 and Noncardiovascular Disease: The Multi‐Ethnic Study of Atherosclerosis |
| title_sort | association between life s simple 7 and noncardiovascular disease the multi ethnic study of atherosclerosis |
| topic | epidemiology Life's Simple 7 prevention risk factor |
| url | https://www.ahajournals.org/doi/10.1161/JAHA.116.003954 |
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